# DAFNA Capital Management LLC 13F holdings

> Latest reported SEC 13F equity book. Teaser: top 10 of 83 long-equity positions.
> CIK 1389933. Latest filing Q1 2026, as of quarter end 2026-03-31. Long-equity book $439.6M.

## Top holdings (teaser)

| # | Ticker | Issuer | Value | % of book | Change |
|---|--------|--------|-------|-----------|--------|
| 1 | n/a | Revolution Medicines Inc | $56.5M | 12.8% | Reduced |
| 2 | n/a | SPDR S&P Biotech ETF | $40.7M | 9.3% | Reduced |
| 3 | n/a | Stereotaxis Inc | $25.2M | 5.7% | Held |
| 4 | n/a | Day One Biopharmaceuticals I | $21.0M | 4.8% | Reduced |
| 5 | n/a | Atricure Inc | $17.0M | 3.9% | Held |
| 6 | n/a | Ideaya Biosciences Inc | $15.9M | 3.6% | Reduced |
| 7 | n/a | Xenon Pharmaceuticals Inc | $14.6M | 3.3% | Reduced |
| 8 | n/a | Cytokinetics Inc | $14.3M | 3.3% | Reduced |
| 9 | n/a | Compass Pathways PLC | $13.4M | 3.0% | Added |
| 10 | n/a | Nektar Therapeutics | $11.9M | 2.7% | Added |

## Latest moves

Bought: Fulcrum Therapeutics Inc, Orthopediatrics Corp, Cytomx Therapeutics Inc
Sold: Revolution Medicines Inc, SPDR S&P Biotech ETF, Day One Biopharmaceuticals I

Counts and totals reflect the 13F filers and securities Arkolith tracks, not the entire institutional universe. Option legs are excluded from the book above.

## Full data via the API and MCP

This page is a teaser. The complete book, full quarter-over-quarter history, and per-datapoint
provenance are available through the metered REST API and MCP server.

- Endpoint: https://arkolith.com/api/mcp (transport: streamable-http)
- Auth: Bearer API key. Mint one and copy a ready-to-paste command at https://arkolith.com/connect
- Claude Code: `claude mcp add --transport http arkolith https://arkolith.com/api/mcp --header "Authorization: Bearer YOUR_API_KEY"`
- Discovery: `tools/list` is free; `tools/call` is metered by credits.

### Machine-readable
- Tool catalog JSON: https://arkolith.com/api/mcp/catalog
- MCP descriptor: https://arkolith.com/.well-known/mcp.json
- OpenAPI 3.1 REST spec: https://arkolith.com/openapi.json
- Full LLM guide: https://arkolith.com/llms-full.txt
- Human docs: https://arkolith.com/docs

## Source and method

- Source: SEC EDGAR 13F-HR (public domain). Long-equity positions only (option legs excluded). Filed quarterly, about a 45-day lag.
- Primary source: https://www.sec.gov/Archives/edgar/data/1389933/000138993326000004/xslForm13F_X02/primary_doc.xml
- Human page: https://arkolith.com/fund/dafna-capital-management-llc-1389933
- Per-datapoint lineage: call the `provenance.get` MCP tool for the source URL and fetch history behind any figure.

Paid product with a one-time evaluation grant at signup (no card to evaluate). Most calls cost 1 credit (~$0.01); heavier point-in-time / cross-source tools cost more.

_Latest disclosed public filings. Data, not investment advice._