The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Mar 7, 2024 | Maier Paul V | Director | Disposed to issuer(D) | 30K | — | — |
| Mar 7, 2024 | Maier Paul V | Director | Disposed to issuer(D) | 12K | — | — |
| Mar 7, 2024 | Maier Paul V | Director | Disposed to issuer(D) | 15K | — | — |
| Mar 7, 2024 | Dalesandro Margaret | Director | Disposed to issuer(D) | 18K | — | — |
| Mar 7, 2024 | Dalesandro Margaret | Director | Disposed to issuer(D) | 10K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 23K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 107K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 50K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 368K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 121K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 61K | — | — |
| Mar 7, 2024 | Nelson Sonja | Chief Financial Officer | Disposed to issuer(D) | 56K | — | — |
| Mar 7, 2024 | Aromando Andrew | Chief Operating Officer | Disposed to issuer(D) | 56K | — | — |
| Mar 7, 2024 | Aromando Andrew | Chief Operating Officer | Disposed to issuer(D) | 100K | — | — |
| Mar 7, 2024 | Aromando Andrew | Chief Operating Officer | Disposed to issuer(D) | 371K | — | — |
| Mar 7, 2024 | Glover Stephen C. | Director | Disposed to issuer(D) | 12K | — | — |
| Mar 7, 2024 | Glover Stephen C. | Director | Disposed to issuer(D) | 6K | — | — |
| Mar 7, 2024 | Glover Stephen C. | Director | Disposed to issuer(D) | 3K | — | — |
| Mar 7, 2024 | Glover Stephen C. | Director | Disposed to issuer(D) | 30K | — | — |
| Mar 7, 2024 | O'Connor Daniel J. | President and CEO, Director | Disposed to issuer(D) | 48K | — | — |
| Mar 7, 2024 | O'Connor Daniel J. | President and CEO, Director | Disposed to issuer(D) | 295K | — | — |
| Mar 7, 2024 | O'Connor Daniel J. | President and CEO, Director | Disposed to issuer(D) | 750K | — | — |
| Mar 7, 2024 | O'Connor Daniel J. | President and CEO, Director | Disposed to issuer(D) | 773K | — | — |
| Mar 7, 2024 | O'Connor Daniel J. | President and CEO, Director | Disposed to issuer(D) | 174K | — | — |
| Mar 7, 2024 | Loesberg Janet | Director | Disposed to issuer(D) | 30K | — | — |
| Mar 7, 2024 | Loesberg Janet | Director | Disposed to issuer(D) | 15K | — | — |
| Mar 7, 2024 | Loesberg Janet | Director | Disposed to issuer(D) | 12K | — | — |
| Mar 7, 2024 | Hermans Kate | Director | Disposed to issuer(D) | 12K | — | — |
| Mar 7, 2024 | Hermans Kate | Director | Disposed to issuer(D) | 30K | — | — |
| Mar 7, 2024 | Hermans Kate | Director | Disposed to issuer(D) | 30K | — | — |
| Mar 7, 2024 | Hermans Kate | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 11, 2023 | O'Connor Daniel J. | President and CEO, Director | Grant(A) | 750K | — | $0 |
| Dec 11, 2023 | Nelson Sonja | Chief Financial Officer | Grant(A) | 50K | — | $0 |
| Dec 11, 2023 | Aromando Andrew | Chief Operating Officer | Grant(A) | 100K | — | $0 |
| Oct 27, 2023 | O'Connor Daniel J. | President and CEO, Director | Sell(S) | 50K | $9.82 | $491K |
| Oct 27, 2023 | Nelson Sonja | Chief Financial Officer | Sell(S) | 13K | $9.82 | $125K |
| Oct 23, 2023 | Cormorant Asset Management, LP | 10% Owner | Buy(P) | 1.3M | $6.99 | $9.1M |
| Sep 18, 2023 | Cormorant Asset Management, LP | 10% Owner | Buy(P) | 751K | $9.24 | $6.9M |
| Sep 15, 2023 | Cormorant Asset Management, LP | 10% Owner | Buy(P) | 1.4M | $9.05 | $12.7M |
| Sep 1, 2023 | Dalesandro Margaret | Director | Grant(A) | 71K | — | $0 |
| Sep 1, 2023 | Dalesandro Margaret | Director | Grant(A) | 125K | — | $0 |
| Jul 5, 2023 | Aromando Andrew | Chief Operating Officer | Grant(A) | 389K | — | $0 |
| Jul 5, 2023 | Nelson Sonja | Chief Financial Officer | Grant(A) | 389K | — | $0 |
| Jul 5, 2023 | O'Connor Daniel J. | President and CEO, Director | Grant(A) | 1.2M | — | $0 |
| Jun 27, 2023 | Darwin Global Master Fund, Ltd. | 10% Owner | Buy(P) | 5.4M | $13.93 | $75.0M |
| Jun 7, 2023 | Hermans Kate | Director | Grant(A) | 85K | — | $0 |
| Jun 7, 2023 | Maier Paul V | Director | Grant(A) | 85K | — | $0 |
| Jun 7, 2023 | Loesberg Janet | Director | Grant(A) | 85K | — | $0 |
| Jun 7, 2023 | Chang Xiaowei | Director | Grant(A) | 85K | — | $0 |
| Jun 7, 2023 | Chang Xiaowei | Director | Grant(A) | 125K | — | $0 |
| Jun 7, 2023 | Glover Stephen C. | Director | Grant(A) | 85K | — | $0 |
| Jun 7, 2023 | Glover Stephen C. | Director | Grant(A) | 40K | — | $0 |
| May 18, 2023 | Glover Stephen C. | Director | Grant(A) | 210K | — | $0 |
| May 18, 2023 | Glover Stephen C. | Director | Grant(A) | 18K | — | $0 |
| Apr 28, 2023 | Aromando Andrew | Chief Operating Officer | Grant(A) | 2.6M | — | $0 |
| Apr 26, 2023 | O'Connor Daniel J. | President and CEO, Director | Grant(A) | 2.8M | — | $0 |
| Apr 26, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Grant(A) | 1.0M | — | $0 |
| Apr 20, 2023 | Chen Bihua | 10% Owner | Buy(P) | 887K | $11.60 | $10.3M |
| Apr 19, 2023 | Chen Bihua | 10% Owner | Buy(P) | 952K | $11.15 | $10.6M |
| Apr 18, 2023 | Chen Bihua | 10% Owner | Buy(P) | 3.4M | $11.27 | $38.1M |
| Apr 17, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 562K | $10.67 | $6.0M |
| Apr 14, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 842K | $9.96 | $8.4M |
| Apr 13, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 1.2M | $9.16 | $10.9M |
| Mar 16, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 500K | $10.15 | $5.1M |
| Mar 15, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 250K | $10.60 | $2.6M |
| Mar 14, 2023 | Cormorant Private Healthcare Fund III LP | 10% Owner | Buy(P) | 250K | $9.95 | $2.5M |
| Mar 6, 2023 | Darwin Global Management, Ltd. | 10% Owner | Buy(P) | 3.6M | $6.50 | $23.5M |
| Feb 28, 2023 | Darwin Global Management, Ltd. | 10% Owner | Buy(P) | 40K | $6.02 | $241K |
| Feb 27, 2023 | Darwin Global Management, Ltd. | 10% Owner | Buy(P) | 65K | $5.48 | $357K |
| Jan 27, 2023 | Hermans Kate | Director | Grant(A) | 210K | — | — |
| Jan 27, 2023 | Hermans Kate | Director | Disposed to issuer(D) | 210K | — | — |
| Jan 27, 2023 | Hermans Kate | Director | Disposed to issuer(D) | 210K | — | — |
| Jan 27, 2023 | Hermans Kate | Director | Grant(A) | 210K | — | — |
| Jan 27, 2023 | Hermans Kate | Director | Disposed to issuer(D) | 105K | — | — |
| Jan 27, 2023 | Hermans Kate | Director | Grant(A) | 105K | — | — |
| Jan 27, 2023 | Loesberg Janet | Director | Grant(A) | 210K | — | — |
| Jan 27, 2023 | Loesberg Janet | Director | Disposed to issuer(D) | 210K | — | — |
| Jan 27, 2023 | Loesberg Janet | Director | Disposed to issuer(D) | 105K | — | — |
| Jan 27, 2023 | Loesberg Janet | Director | Grant(A) | 105K | — | — |
| Jan 27, 2023 | Maier Paul V | Director | Disposed to issuer(D) | 210K | — | — |
| Jan 27, 2023 | Maier Paul V | Director | Disposed to issuer(D) | 105K | — | — |
| Jan 27, 2023 | Maier Paul V | Director | Grant(A) | 105K | — | — |
| Jan 27, 2023 | Maier Paul V | Director | Grant(A) | 210K | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Disposed to issuer(D) | 2.6M | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Grant(A) | 2.6M | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Disposed to issuer(D) | 850K | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Grant(A) | 425K | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Disposed to issuer(D) | 425K | — | — |
| Jan 27, 2023 | Nelson Sonja | Chief Fin. & Operating Officer | Grant(A) | 850K | — | — |
| Jan 27, 2023 | Rupalla Katrin | Director | Grant(A) | 105K | — | — |
| Jan 27, 2023 | Rupalla Katrin | Director | Disposed to issuer(D) | 105K | — | — |
| Jan 27, 2023 | Rupalla Katrin | Director | Grant(A) | 200K | — | — |
| Jan 27, 2023 | Rupalla Katrin | Director | Disposed to issuer(D) | 200K | — | — |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).