The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 14, 2026 | Dambkowski Carl | Chief Medical Officer | Gift(G) | 8K | — | $0 |
| Jul 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Gift(G) | 75K | — | $0 |
| Jul 8, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 20K | $133.63 | $2.7M |
| Jul 1, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| Jul 1, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 6K | $132.74 | $730K |
| Jul 1, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| Jun 22, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 80K | $132.54 | $10.6M |
| Jun 22, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 26K | $132.60 | $3.5M |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 7K | $82.21 | $557K |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 8K | $82.78 | $634K |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 1K | $84.18 | $91K |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 2K | $85.19 | $134K |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 2K | $86.27 | $199K |
| Jun 10, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 614 | $86.89 | $53K |
| Jun 9, 2026 | Fairmount Funds Management LLC | Director | Grant(A) | 8K | — | $0 |
| Jun 9, 2026 | Shah Nimish P | Director | Grant(A) | 8K | — | $0 |
| Jun 9, 2026 | McKenna Mark C. | Director | Grant(A) | 8K | — | $0 |
| Jun 9, 2026 | Jones William A JR | Director | Grant(A) | 8K | — | $0 |
| Jun 9, 2026 | Fox Jennifer A. | Director | Grant(A) | 8K | — | $0 |
| Jun 9, 2026 | Bollinger Lisa | Director | Grant(A) | 8K | — | $0 |
| Jun 3, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| Jun 3, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 6K | $78.71 | $433K |
| Jun 3, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| May 13, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 1K | $82.58 | $111K |
| May 13, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 19K | $82.05 | $1.5M |
| May 6, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| May 6, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 2K | $84.60 | $152K |
| May 6, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 4K | $83.92 | $311K |
| May 6, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| May 1, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 289 | $83.16 | $24K |
| May 1, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 900 | $82.60 | $74K |
| May 1, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 811 | $81.02 | $66K |
| Apr 16, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Option exercise(M) | 3K | — | $0 |
| Apr 16, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Option exercise(M) | 3K | $22.86 | $69K |
| Apr 16, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $90.00 | $180K |
| Apr 8, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 200 | $85.00 | $17K |
| Apr 8, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 2K | $83.26 | $167K |
| Apr 8, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 18K | $82.48 | $1.5M |
| Apr 1, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| Apr 1, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 100 | $85.89 | $9K |
| Apr 1, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 3K | $85.33 | $231K |
| Apr 1, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 3K | $84.31 | $227K |
| Apr 1, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| Apr 1, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 1K | $85.46 | $94K |
| Apr 1, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 900 | $84.46 | $76K |
| Mar 25, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $85.00 | $170K |
| Mar 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 3K | $75.86 | $259K |
| Mar 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 8K | $74.83 | $615K |
| Mar 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 8K | $74.29 | $621K |
| Mar 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 2K | $71.98 | $149K |
| Mar 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 3K | $70.33 | $227K |
| Mar 4, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| Mar 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 200 | $73.26 | $15K |
| Mar 4, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| Mar 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 300 | $69.43 | $21K |
| Mar 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 994 | $70.45 | $70K |
| Mar 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 300 | $68.27 | $20K |
| Mar 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 406 | $71.66 | $29K |
| Feb 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 11K | $62.96 | $724K |
| Feb 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 955 | $64.99 | $62K |
| Feb 11, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 8K | $63.73 | $481K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 100 | $67.88 | $7K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 2K | $64.88 | $161K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | $22.86 | $94K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 1K | $66.85 | $87K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 1K | $65.83 | $93K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 200 | $68.94 | $14K |
| Feb 4, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 4K | — | $0 |
| Feb 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 1K | $66.15 | $73K |
| Feb 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 792 | $65.21 | $52K |
| Feb 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 100 | $66.89 | $7K |
| Jan 22, 2026 | Harwin Peter Evan | Director | Sell(S) | 1.8M | $76.30 | $133.5M |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 8K | $79.82 | $677K |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 2K | $81.00 | $192K |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 2K | $82.41 | $153K |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 470 | $83.79 | $39K |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 1K | $78.64 | $113K |
| Jan 14, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 5K | $83.16 | $448K |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 14K | $22.86 | $321K |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 15K | $77.90 | $1.2M |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 826 | $79.04 | $65K |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 100 | $80.06 | $8K |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 3K | $77.13 | $228K |
| Jan 7, 2026 | Dambkowski Carl | Chief Medical Officer | Option exercise(M) | 14K | — | $0 |
| Jan 6, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $80.00 | $160K |
| Jan 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 4K | $75.20 | $307K |
| Jan 2, 2026 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $74.13 | $142K |
| Jan 2, 2026 | Henderson Jane | Chief Financial Officer | Grant(A) | 84K | — | $0 |
| Jan 2, 2026 | Henderson Michael Thomas | Chief Executive Officer, Director | Grant(A) | 253K | — | $0 |
| Jan 2, 2026 | Dambkowski Carl | Chief Medical Officer | Grant(A) | 84K | — | $0 |
| Dec 19, 2025 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $80.00 | $120K |
| Dec 10, 2025 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 9K | $74.88 | $706K |
| Dec 10, 2025 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 10K | $75.79 | $758K |
| Dec 10, 2025 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 560 | $76.58 | $43K |
| Dec 4, 2025 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 40K | $75.01 | $3.0M |
| Dec 4, 2025 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $75.00 | $113K |
| Dec 4, 2025 | Dambkowski Carl | Chief Medical Officer | Sell(S) | 11K | $75.00 | $818K |
| Nov 25, 2025 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $70.00 | $105K |
| Nov 14, 2025 | Henderson Jane | Chief Financial Officer | Sell(S) | 2K | $65.00 | $130K |
| Nov 13, 2025 | Henderson Michael Thomas | Chief Executive Officer, Director | Sell(S) | 3K | $61.93 | $207K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-21. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).