The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 16, 2026 | Fairmount Funds Management LLC | Director, 10% Owner | Buy(P) | 526K | $14.50 | $7.6M |
| Jul 16, 2026 | Fairmount Funds Management LLC | Director, 10% Owner | Buy(P) | 853K | $14.50 | $12.4M |
| Jun 22, 2026 | McNeill Jonathan | President and COO | Sell(S) | 21K | $17.99 | $370K |
| Jun 22, 2026 | Im Ellie Eunkyung | Chief Medical Officer | Sell(S) | 1K | $17.99 | $22K |
| Jun 22, 2026 | Scalzo Richard William | Chief Financial Officer | Sell(S) | 1K | $17.99 | $20K |
| Jun 22, 2026 | Pinkas Jan | Chief Scientific Officer | Sell(S) | 1K | $17.99 | $23K |
| Jun 22, 2026 | Lynch Ryan | See Remarks | Sell(S) | 465 | $17.99 | $8K |
| Jun 22, 2026 | Bispham Barbara Harlin | See Remarks | Sell(S) | 1K | $17.99 | $22K |
| Jun 22, 2026 | Brumm Joshua T | Chief Executive Officer, Director | Sell(S) | 42K | $17.99 | $761K |
| Jun 2, 2026 | Violin Jonathan | Director | Grant(A) | 11K | — | $0 |
| Jun 2, 2026 | Lubner David Charles | Director | Grant(A) | 11K | — | $0 |
| Jun 2, 2026 | Balcom Alexandra | Director | Grant(A) | 11K | — | $0 |
| Jun 2, 2026 | Moran Susan | Director | Grant(A) | 11K | — | $0 |
| Jun 2, 2026 | Fairmount Funds Management LLC | Director, 10% Owner | Grant(A) | 11K | — | $0 |
| Dec 15, 2025 | Bispham Barbara Harlin | See Remarks | Grant(A) | 6K | — | — |
| Dec 15, 2025 | Bispham Barbara Harlin | See Remarks | Grant(A) | 12K | — | — |
| Dec 15, 2025 | Bispham Barbara Harlin | See Remarks | Grant(A) | 72K | — | $0 |
| Dec 15, 2025 | Lynch Ryan | See Remarks | Grant(A) | 8K | — | — |
| Dec 15, 2025 | Lynch Ryan | See Remarks | Grant(A) | 4K | — | — |
| Dec 15, 2025 | Lynch Ryan | See Remarks | Grant(A) | 34K | — | $0 |
| Dec 15, 2025 | Im Ellie Eunkyung | Chief Medical Officer | Grant(A) | 5K | — | — |
| Dec 15, 2025 | Im Ellie Eunkyung | Chief Medical Officer | Grant(A) | 16K | — | — |
| Dec 15, 2025 | Im Ellie Eunkyung | Chief Medical Officer | Grant(A) | 65K | — | $0 |
| Dec 15, 2025 | McNeill Jonathan | President and COO | Grant(A) | 20K | — | — |
| Dec 15, 2025 | McNeill Jonathan | President and COO | Grant(A) | 6K | — | — |
| Dec 15, 2025 | McNeill Jonathan | President and COO | Grant(A) | 78K | — | $0 |
| Dec 15, 2025 | Scalzo Richard William | Chief Financial Officer | Grant(A) | 14K | — | — |
| Dec 15, 2025 | Scalzo Richard William | Chief Financial Officer | Grant(A) | 5K | — | — |
| Dec 15, 2025 | Scalzo Richard William | Chief Financial Officer | Grant(A) | 58K | — | $0 |
| Dec 15, 2025 | Brumm Joshua T | Chief Executive Officer, Director | Grant(A) | 45K | — | — |
| Dec 15, 2025 | Brumm Joshua T | Chief Executive Officer, Director | Grant(A) | 10K | — | — |
| Dec 15, 2025 | Brumm Joshua T | Chief Executive Officer, Director | Grant(A) | 180K | — | $0 |
| Dec 15, 2025 | Doughty Christopher Grant | Chief Business Officer | Grant(A) | 15K | — | — |
| Dec 15, 2025 | Doughty Christopher Grant | Chief Business Officer | Grant(A) | 8K | — | — |
| Dec 15, 2025 | Doughty Christopher Grant | Chief Business Officer | Grant(A) | 59K | — | $0 |
| Dec 15, 2025 | Pinkas Jan | Chief Scientific Officer | Grant(A) | 5K | — | — |
| Dec 15, 2025 | Pinkas Jan | Chief Scientific Officer | Grant(A) | 18K | — | — |
| Dec 15, 2025 | Pinkas Jan | Chief Scientific Officer | Grant(A) | 70K | — | $0 |
| Dec 8, 2025 | Brumm Joshua T | Chief Executive Officer, Director | Grant(A) | 346K | — | $0 |
| Dec 8, 2025 | McNeill Jonathan | President and COO | Grant(A) | 173K | — | $0 |
| Dec 4, 2025 | Harwin Peter Evan | Director, 10% Owner | Buy(P) | 1.4M | $13.41 | $18.2M |
| Dec 4, 2025 | Harwin Peter Evan | Director, 10% Owner | Buy(P) | 131K | $13.41 | $1.8M |
| Jul 16, 2025 | Pinkas Jan | Chief Scientific Officer | Grant(A) | 142K | — | $0 |
| Jun 23, 2025 | Lubner David Charles | Director | Grant(A) | 9K | — | $0 |
| Jun 23, 2025 | Balcom Alexandra | Director | Grant(A) | 9K | — | $0 |
| Jun 23, 2025 | Violin Jonathan | Director | Grant(A) | 9K | — | $0 |
| Jun 23, 2025 | Harwin Peter Evan | Director, 10% Owner | Grant(A) | 9K | — | $0 |
| Jun 23, 2025 | Moran Susan | Director | Grant(A) | 9K | — | $0 |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 56K | — | — |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 557K | — | — |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 657K | — | — |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 26K | — | — |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 258K | — | — |
| Jun 13, 2025 | BVF GP Holdings LLC | 10% Owner | Other(J) | 304K | — | — |
| Oct 27, 2023 | GNI Hong Kong Ltd | 10% Owner | Other(J) | 5.4M | — | — |
| Oct 27, 2023 | GNI Hong Kong Ltd | 10% Owner | Other(J) | 11K | — | — |
| Aug 31, 2023 | Lawlor Augustine | Director | Disposed to issuer(D) | 24 | — | — |
| Aug 31, 2023 | Lawlor Augustine | Director | Disposed to issuer(D) | 25 | — | — |
| Aug 31, 2023 | GNI Hong Kong Ltd | 10% Owner | Disposed to issuer(D) | 5K | — | — |
| Aug 31, 2023 | GNI Hong Kong Ltd | 10% Owner | Disposed to issuer(D) | 895 | — | — |
| Aug 31, 2023 | Usman Nassim | President & CEO, Director | Disposed to issuer(D) | 1 | — | — |
| Aug 31, 2023 | Usman Nassim | President & CEO, Director | Disposed to issuer(D) | 8 | — | — |
| Aug 31, 2023 | Usman Nassim | President & CEO, Director | Disposed to issuer(D) | 25 | — | — |
| Aug 31, 2023 | Hunt Andrea | Director | Disposed to issuer(D) | 28 | — | — |
| Aug 31, 2023 | Miller Seline E. | SVP Finance; Interim CFO & PAO | Disposed to issuer(D) | 7 | — | — |
| Aug 9, 2022 | Blouse Grant E. | Chief Scientific Officer | Buy(P) | 3K | $0.47 | $2K |
| Aug 9, 2022 | Miller Seline E. | SVP Finance; Interim CFO & PAO | Buy(P) | 3K | $0.47 | $2K |
| Aug 9, 2022 | Usman Nassim | President & CEO, Director | Buy(P) | 3K | $0.47 | $2K |
| Feb 11, 2022 | Blouse Grant E. | Chief Scientific Officer | Grant(A) | 200K | — | $0 |
| Feb 11, 2022 | Miller Seline E. | SVP Finance; Interim CFO & PAO | Grant(A) | 108K | — | $0 |
| Feb 9, 2022 | Blouse Grant E. | Chief Scientific Officer | Buy(P) | 3K | $0.46 | $1K |
| Feb 9, 2022 | Miller Seline E. | SVP Finance; Interim CFO & PAO | Buy(P) | 3K | $0.46 | $1K |
| Feb 9, 2022 | Usman Nassim | President & CEO, Director | Buy(P) | 3K | $0.46 | $1K |
| Jan 7, 2022 | Hunt Andrea | Director | Grant(A) | 8K | — | $0 |
| Jan 7, 2022 | Ling Geoffrey M.D. | Director | Grant(A) | 13K | — | $0 |
| Jan 7, 2022 | Williams Eddie | Director | Grant(A) | 12K | — | $0 |
| Oct 1, 2021 | Desouza Errol B | Director | Grant(A) | 4K | — | $0 |
| Oct 1, 2021 | Hunt Andrea | Director | Grant(A) | 2K | — | $0 |
| Oct 1, 2021 | Lawlor Augustine | Director | Grant(A) | 6K | — | $0 |
| Oct 1, 2021 | Ling Geoffrey M.D. | Director | Grant(A) | 3K | — | $0 |
| Oct 1, 2021 | Williams Eddie | Director | Grant(A) | 3K | — | $0 |
| Sep 9, 2021 | Jew Jeanne Y | Director | Grant(A) | 28K | — | $0 |
| Aug 9, 2021 | Blouse Grant E. | Chief Scientific Officer | Buy(P) | 1K | $3.62 | $4K |
| Aug 9, 2021 | Levy Howard | Chief Medical Officer | Buy(P) | 639 | $3.62 | $2K |
| Aug 9, 2021 | Usman Nassim | President & CEO, Director | Buy(P) | 867 | $3.62 | $3K |
| Jul 1, 2021 | Desouza Errol B | Director | Grant(A) | 3K | — | $0 |
| Jul 1, 2021 | Hunt Andrea | Director | Grant(A) | 3K | — | $0 |
| Jul 1, 2021 | Lawlor Augustine | Director | Grant(A) | 6K | — | $0 |
| Jul 1, 2021 | Ling Geoffrey M.D. | Director | Grant(A) | 3K | — | $0 |
| Jul 1, 2021 | Williams Eddie | Director | Grant(A) | 1K | — | $0 |
| Jun 9, 2021 | Desouza Errol B | Director | Grant(A) | 14K | — | $0 |
| Jun 9, 2021 | Hunt Andrea | Director | Grant(A) | 14K | — | $0 |
| Jun 9, 2021 | Lawlor Augustine | Director | Grant(A) | 14K | — | $0 |
| Jun 9, 2021 | Ling Geoffrey M.D. | Director | Grant(A) | 14K | — | $0 |
| Jun 9, 2021 | Tetlow Sharon | Director | Grant(A) | 14K | — | $0 |
| Jun 9, 2021 | Williams Eddie | Director | Grant(A) | 14K | — | $0 |
| Apr 5, 2021 | Usman Nassim | President & CEO, Director | Option exercise(M) | 5K | $4.63 | $23K |
| Apr 5, 2021 | Usman Nassim | President & CEO, Director | Option exercise(M) | 5K | — | $0 |
| Apr 1, 2021 | Desouza Errol B | Director | Grant(A) | 3K | — | $0 |
| Apr 1, 2021 | Hunt Andrea | Director | Grant(A) | 2K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-21. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).