The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 17, 2026 | De Vre Raymond | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Dilly Stephen George | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Martinborough Esther | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Collins Cynthia | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Smith David V | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Richards Christos | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Singhvi Rahul | Director | Grant(A) | 66K | — | $0 |
| Jun 17, 2026 | Parker H Stewart | Director | Grant(A) | 66K | — | $0 |
| Jun 11, 2026 | De Vre Raymond | Director | Sell(S) | 3K | $2.37 | $6K |
| Feb 24, 2026 | Lutz Stefan | Chief Scientific Officer | Sell(S) | 6K | $1.13 | $7K |
| Feb 23, 2026 | Erbez Georgia | See Remarks | Grant(A) | 316K | — | $0 |
| Feb 23, 2026 | Moore Alison | President and CEO, Director | Grant(A) | 993K | — | $0 |
| Feb 23, 2026 | Lutz Stefan | Chief Scientific Officer | Grant(A) | 316K | — | $0 |
| Feb 6, 2026 | Moore Alison | President and CEO, Director | Sell(S) | 4K | $1.31 | $5K |
| Feb 6, 2026 | Erbez Georgia | See Remarks | Sell(S) | 4K | $1.31 | $5K |
| Feb 6, 2026 | Lutz Stefan | Chief Scientific Officer | Sell(S) | 2K | $1.31 | $3K |
| Jan 7, 2026 | Lutz Stefan | CSO | Sell(S) | 5K | $1.70 | $8K |
| Dec 1, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 245K | $1.67 | $409K |
| Dec 1, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 9K | $1.67 | $14K |
| Nov 28, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 2K | $1.75 | $4K |
| Nov 28, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 105K | $1.75 | $184K |
| Nov 26, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 5K | $1.74 | $9K |
| Nov 26, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 148K | $1.74 | $258K |
| Nov 21, 2025 | Wolf Dennis P | Director | Sell(S) | 9K | $1.56 | $14K |
| Nov 13, 2025 | Moore Alison | President and CEO | Grant(A) | 85K | — | $0 |
| Nov 13, 2025 | Moore Alison | President and CEO | Grant(A) | 500K | — | $0 |
| Nov 12, 2025 | Opaleye Management Inc. | 10% Owner | Buy(S) | 890K | $1.94 | $1.7M |
| Nov 12, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 27K | $1.94 | $53K |
| Nov 12, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 165K | $1.96 | $323K |
| Nov 11, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 535K | $1.80 | $963K |
| Nov 11, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 13K | $1.80 | $24K |
| Nov 11, 2025 | Dilly Stephen George | Director | Grant(A) | 50K | $1.85 | $93K |
| Nov 11, 2025 | De Vre Raymond | Director | Sell(S) | 1K | $1.74 | $2K |
| Nov 10, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 205K | $1.73 | $355K |
| Nov 10, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 3K | $1.73 | $6K |
| Nov 7, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 297K | $1.70 | $504K |
| Nov 7, 2025 | Opaleye Management Inc. | 10% Owner | Sell(S) | 10K | $1.70 | $17K |
| Oct 13, 2025 | Erbez Georgia | Chief Financial Officer | Sell(S) | 6K | $2.51 | $16K |
| Oct 13, 2025 | Moore Alison | Chief Technical Officer | Sell(S) | 6K | $2.51 | $16K |
| Aug 4, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 780 | $2.84 | $2K |
| Jul 31, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 84K | $2.68 | $226K |
| Jul 30, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 2K | $2.80 | $4K |
| Jul 29, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 8K | $2.82 | $24K |
| Jul 18, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 100K | $2.82 | $282K |
| Jun 27, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 100K | $2.39 | $239K |
| Jun 16, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 51K | $2.24 | $114K |
| Jun 13, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 99K | $2.23 | $221K |
| Jun 12, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 100K | $2.25 | $225K |
| Jun 10, 2025 | Collins Cynthia | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | De Vre Raymond | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Martinborough Esther | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Parker H Stewart | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Richards Christos | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Singhvi Rahul | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Smith David V | Director | Grant(A) | 41K | — | $0 |
| Jun 10, 2025 | Wolf Dennis P | Director | Grant(A) | 41K | — | $0 |
| May 28, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 5K | $2.36 | $12K |
| May 23, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 2.3M | $2.36 | $5.5M |
| May 1, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 20K | $2.32 | $46K |
| Apr 30, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 25K | $2.31 | $58K |
| Apr 25, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 25K | $2.24 | $56K |
| Apr 17, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 45K | $2.09 | $94K |
| Apr 16, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 70K | $2.13 | $149K |
| Apr 15, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 25K | $2.23 | $56K |
| Apr 8, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 100K | $1.98 | $198K |
| Apr 3, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 75K | $2.30 | $173K |
| Apr 2, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 5K | $2.46 | $12K |
| Apr 1, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 35K | $2.48 | $87K |
| Mar 28, 2025 | Collins Cynthia | Director | Grant(A) | 71K | — | $0 |
| Mar 21, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 93K | $2.54 | $236K |
| Mar 20, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 7 | $2.54 | $18 |
| Mar 13, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 85K | $2.54 | $216K |
| Mar 6, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 100K | $2.61 | $261K |
| Mar 5, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 10K | $2.69 | $27K |
| Mar 4, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 55K | $2.64 | $145K |
| Mar 3, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 47K | $2.81 | $133K |
| Feb 28, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 148K | $2.99 | $441K |
| Feb 12, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 15K | $4.00 | $60K |
| Feb 11, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 13K | $4.11 | $51K |
| Feb 10, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 23K | $4.18 | $94K |
| Feb 5, 2025 | Dilly Stephen George | See Remarks, Director | Grant(A) | 89K | — | $0 |
| Feb 5, 2025 | Dilly Stephen George | See Remarks, Director | Grant(A) | 533K | — | $0 |
| Feb 5, 2025 | Erbez Georgia | Chief Financial Officer | Grant(A) | 27K | — | $0 |
| Feb 5, 2025 | Erbez Georgia | Chief Financial Officer | Grant(A) | 161K | — | $0 |
| Feb 5, 2025 | Moore Alison | Chief Technical Officer | Grant(A) | 27K | — | $0 |
| Feb 5, 2025 | Moore Alison | Chief Technical Officer | Grant(A) | 161K | — | $0 |
| Feb 5, 2025 | Norrett Kevin | Chief Operating Officer | Grant(A) | 27K | — | $0 |
| Feb 5, 2025 | Norrett Kevin | Chief Operating Officer | Grant(A) | 161K | — | $0 |
| Jan 31, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 45K | $4.29 | $193K |
| Jan 30, 2025 | Opaleye Management Inc. | 10% Owner | Buy(P) | 20K | $4.49 | $90K |
| Jan 14, 2025 | Richards Christos | Director | Grant(A) | 44K | — | $0 |
| Dec 31, 2024 | Opaleye Management Inc. | 10% Owner | Buy(P) | 10K | $4.66 | $47K |
| Dec 30, 2024 | Opaleye Management Inc. | 10% Owner | Buy(P) | 35K | $4.70 | $165K |
| Nov 7, 2024 | De Vre Raymond | Director | Grant(A) | 48K | — | $0 |
| Oct 25, 2024 | Opaleye Management Inc. | 10% Owner | Buy(P) | 25K | $2.91 | $73K |
| Oct 10, 2024 | Erbez Georgia | Chief Financial Officer | Grant(A) | 50K | — | $0 |
| Oct 10, 2024 | Erbez Georgia | Chief Financial Officer | Grant(A) | 300K | — | $0 |
| Oct 10, 2024 | Moore Alison | Chief Technical Officer | Grant(A) | 50K | — | $0 |
| Oct 10, 2024 | Moore Alison | Chief Technical Officer | Grant(A) | 300K | — | $0 |
| Sep 25, 2024 | Opaleye Management Inc. | 10% Owner | Buy(P) | 5K | $2.86 | $14K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).