The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Mar 20, 2024 | Leonard Braden Michael | 10% Owner | Buy(P) | 171K | $2.95 | $503K |
| Mar 18, 2024 | Leonard Braden Michael | 10% Owner | Buy(P) | 114K | $3.01 | $342K |
| Mar 4, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 6K | $1.69 | $11K |
| Mar 4, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 6K | — | $0 |
| Mar 4, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | $1.69 | $4K |
| Mar 4, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | — | $0 |
| Feb 29, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 3K | $1.20 | $3K |
| Feb 29, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 13K | $1.69 | $21K |
| Feb 29, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 3K | — | $0 |
| Feb 29, 2024 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 13K | — | $0 |
| Feb 29, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 3K | $1.68 | $5K |
| Feb 29, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 5K | $1.69 | $8K |
| Feb 29, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 3K | — | $0 |
| Feb 29, 2024 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 5K | — | $0 |
| Feb 14, 2024 | George Jean | Director | Option exercise(M) | 14K | $1.69 | $24K |
| Feb 14, 2024 | George Jean | Director | Option exercise(M) | 14K | — | $0 |
| Feb 9, 2024 | Sands Stephen H. | Director | Option exercise(M) | 12K | $1.69 | $20K |
| Feb 9, 2024 | Sands Stephen H. | Director | Option exercise(M) | 12K | — | $0 |
| Feb 8, 2024 | Thero John F | Director | Option exercise(M) | 13K | $1.69 | $22K |
| Feb 8, 2024 | Thero John F | Director | Option exercise(M) | 13K | — | $0 |
| Feb 6, 2024 | Zakrzewski Joseph S | Director | Option exercise(M) | 14K | $1.69 | $24K |
| Feb 6, 2024 | Zakrzewski Joseph S | Director | Option exercise(M) | 14K | — | $0 |
| Dec 11, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 3K | — | $0 |
| Dec 11, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 6K | — | $0 |
| Dec 11, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | $1.68 | $3K |
| Dec 11, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | $1.69 | $4K |
| Dec 11, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | — | $0 |
| Dec 11, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 2K | — | $0 |
| Nov 20, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 53K | $1.68 | $88K |
| Nov 20, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 21K | $1.69 | $36K |
| Nov 20, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 53K | — | $0 |
| Nov 20, 2023 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 21K | — | $0 |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 57K | $1.69 | $96K |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 28K | $1.20 | $33K |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 57K | — | $0 |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 28K | — | $0 |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 3K | $1.20 | $3K |
| Nov 20, 2023 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 6K | $1.69 | $11K |
| Jul 20, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 100K | $2.75 | $275K |
| Jul 19, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 2K | $2.76 | $5K |
| Jul 18, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 7K | $2.76 | $18K |
| Jul 17, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 21K | $2.75 | $58K |
| Jul 14, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 11K | $2.74 | $30K |
| Jun 30, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 201K | $2.63 | $528K |
| Jun 27, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 32K | $1.77 | $57K |
| Jun 26, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 8K | $1.79 | $15K |
| Jun 23, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 3K | $1.88 | $6K |
| Jun 22, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 5K | $1.94 | $10K |
| Jun 21, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 5K | $1.99 | $10K |
| Jun 20, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 744 | $2.11 | $2K |
| Jun 16, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 6K | $2.03 | $12K |
| Jun 15, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 10K | $2.03 | $20K |
| Jun 14, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 3K | $2.11 | $6K |
| Jun 13, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 3K | $2.10 | $6K |
| Jun 12, 2023 | Novo Holdings A/S | 10% Owner | Sell(S) | 900 | $2.06 | $2K |
| Feb 3, 2023 | Renschler Markus MD | President and CEO, Director | Grant(A) | 303K | — | $0 |
| Feb 3, 2023 | Veness Adam M | General Counsel | Grant(A) | 96K | — | $0 |
| Feb 3, 2023 | Gaiero David G | Chief Financial Officer | Grant(A) | 114K | — | $0 |
| Feb 3, 2023 | Bracken Racquel | Director | Grant(A) | 14K | — | $0 |
| Feb 3, 2023 | George Jean | Director | Grant(A) | 14K | — | $0 |
| Feb 3, 2023 | Humphrey Jeffrey | Director | Grant(A) | 14K | — | $0 |
| Feb 3, 2023 | Molineaux Susan | Director | Grant(A) | 14K | — | $0 |
| Feb 3, 2023 | Romberger Timothy | Director | Grant(A) | 14K | — | $0 |
| Feb 3, 2023 | Sands Stephen H. | Director | Grant(A) | 12K | — | $0 |
| Feb 3, 2023 | Thero John F | Director | Grant(A) | 13K | — | $0 |
| Feb 3, 2023 | Zakrzewski Joseph S | Director | Grant(A) | 14K | — | $0 |
| Jan 13, 2023 | Renschler Markus MD | President and CEO, Director | Grant(A) | 5K | $1.49 | $7K |
| Jan 13, 2023 | Gaiero David G | Chief Financial Officer | Grant(A) | 5K | $1.49 | $7K |
| Dec 21, 2022 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 106K | $1.03 | $110K |
| Dec 21, 2022 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 30K | $1.20 | $37K |
| Dec 21, 2022 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 30K | — | $0 |
| Dec 21, 2022 | Renschler Markus MD | President and CEO, Director | Option exercise(M) | 106K | — | $0 |
| Dec 7, 2022 | Zakrzewski Joseph S | Director | Buy(P) | 21K | $1.30 | $28K |
| Jul 20, 2022 | Novo Holdings A/S | 10% Owner | Sell(S) | 900K | $3.00 | $2.7M |
| May 12, 2022 | Zakrzewski Joseph S | Director | Buy(P) | 743 | $1.61 | $1K |
| May 11, 2022 | Zakrzewski Joseph S | Director | Buy(P) | 1K | $1.70 | $2K |
| May 10, 2022 | Zakrzewski Joseph S | Director | Buy(P) | 49K | $1.89 | $93K |
| May 10, 2022 | Thero John F | Director | Buy(P) | 10K | $2.00 | $20K |
| May 2, 2022 | Veness Adam M | General Counsel | Grant(A) | 177K | — | $0 |
| Feb 22, 2022 | Sands Stephen H. | Director | Grant(A) | 28K | — | $0 |
| Feb 22, 2022 | Gaiero David G | Vice President, Finance | Grant(A) | 23K | — | $0 |
| Feb 22, 2022 | Gengos Andrew | Chief Business Officer | Grant(A) | 35K | — | $0 |
| Feb 22, 2022 | Secrist John Paul | Chief Scientific Officer | Grant(A) | 42K | — | $0 |
| Feb 22, 2022 | Naesens Janwillem | Director | Grant(A) | 14K | — | $0 |
| Feb 22, 2022 | Romberger Timothy | Director | Grant(A) | 14K | — | $0 |
| Feb 22, 2022 | George Jean | Director | Grant(A) | 14K | — | $0 |
| Feb 22, 2022 | Bracken Racquel | Director | Grant(A) | 14K | — | $0 |
| Feb 22, 2022 | Humphrey Jeffrey | Director | Grant(A) | 2K | — | $0 |
| Feb 22, 2022 | Molineaux Susan | Director | Grant(A) | 14K | — | $0 |
| Feb 22, 2022 | Renschler Markus MD | President and CEO, Director | Grant(A) | 106K | — | $0 |
| Feb 22, 2022 | Zakrzewski Joseph S | Director | Grant(A) | 14K | — | $0 |
| Feb 4, 2022 | Thero John F | Director | Grant(A) | 28K | — | $0 |
| Dec 28, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 601 | $9.85 | $6K |
| Dec 27, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 200 | $9.97 | $2K |
| Dec 27, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 99 | $10.18 | $1K |
| Dec 23, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 200 | $9.87 | $2K |
| Dec 20, 2021 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 4K | $1.68 | $7K |
| Dec 20, 2021 | Gaiero David G | Chief Financial Officer | Option exercise(M) | 4K | — | $0 |
| Dec 17, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 200 | $9.88 | $2K |
| Dec 15, 2021 | Zakrzewski Joseph S | Director | Buy(P) | 2K | $11.12 | $19K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).