| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 15, 2026 | FILLER LINDA | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | FILLER LINDA | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | Couchara Georgeann | SVP, Human Resources | disposed(F) | 281 | $161.91 | $45K |
| May 15, 2026 | Stevens Raymond C | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | Stevens Raymond C | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | SPOON ALAN G | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | SPOON ALAN G | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | Sanders A Shane | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | Sanders A Shane | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | List Teri | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | List Teri | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | Zerhouni Elias A. | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | Zerhouni Elias A. | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | Dewan Feroz | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | Dewan Feroz | Director | acquired(A) | 1.7K | — | $0 |
| May 15, 2026 | Lamanna Charles W | Director | acquired(A) | 680 | — | $0 |
| May 15, 2026 | Lamanna Charles W | Director | acquired(A) | 1.7K | — | $0 |
| May 1, 2026 | SPOON ALAN G | Director | acquired(M) | 3.3K | $71.88 | $237K |
| May 1, 2026 | SPOON ALAN G | Director | Sell(S) | 1.4K | $174.67 | $237K |
| May 1, 2026 | SPOON ALAN G | Director | disposed(M) | 3.3K | — | $0 |
| Apr 24, 2026 | Stevens Raymond C | Director | acquired(A) | 199.26 | $177.25 | $35K |
| Apr 24, 2026 | Sanders A Shane | Director | acquired(A) | 231.809 | $177.25 | $41K |
| Apr 24, 2026 | List Teri | Director | acquired(A) | 17.248 | $177.25 | $3K |
| Apr 24, 2026 | Zerhouni Elias A. | Director | acquired(A) | 259.718 | $177.25 | $46K |
| Apr 24, 2026 | FILLER LINDA | Director | acquired(A) | 20.121 | $177.25 | $4K |
| Apr 24, 2026 | SPOON ALAN G | Director | acquired(A) | 252.322 | $177.25 | $45K |
| Apr 24, 2026 | Dewan Feroz | Director | acquired(A) | 187.894 | $177.25 | $33K |
| Mar 1, 2026 | Leiken Jonathan | SVP-Chief Legal Officer | acquired(A) | 2.4K | — | $0 |
| Mar 1, 2026 | Leiken Jonathan | SVP-Chief Legal Officer | acquired(A) | 6.4K | — | $0 |
| Mar 1, 2026 | McGrew Matthew | Executive Vice President | acquired(A) | 5.9K | — | $0 |
| Mar 1, 2026 | McGrew Matthew | Executive Vice President | acquired(A) | 16.0K | — | $0 |
| Mar 1, 2026 | Milosevich Gregory M | Executive Vice President | acquired(A) | 4.3K | — | $0 |
| Mar 1, 2026 | Milosevich Gregory M | Executive Vice President | disposed(F) | 118 | $210.64 | $25K |
| Mar 1, 2026 | Milosevich Gregory M | Executive Vice President | acquired(A) | 11.5K | — | $0 |
| Mar 1, 2026 | Bouda Christopher | VP, Chief Accounting Officer | acquired(A) | 1.2K | — | $0 |
| Mar 1, 2026 | Bouda Christopher | VP, Chief Accounting Officer | disposed(F) | 170 | $210.64 | $36K |
| Mar 1, 2026 | Bouda Christopher | VP, Chief Accounting Officer | acquired(A) | 3.4K | — | $0 |
| Mar 1, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | acquired(A) | 6.6K | — | $0 |
| Mar 1, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | disposed(F) | 284 | $210.64 | $60K |
| Mar 1, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | acquired(A) | 18.0K | — | $0 |
| Mar 1, 2026 | Riley Christopher Paul | Executive Vice President | acquired(A) | 6.2K | — | $0 |
| Mar 1, 2026 | Riley Christopher Paul | Executive Vice President | disposed(F) | 1.1K | $210.64 | $235K |
| Mar 1, 2026 | Riley Christopher Paul | Executive Vice President | acquired(A) | 16.7K | — | $0 |
| Mar 1, 2026 | GRAY R BRADLEY | SVP Strategic Development | acquired(A) | 2.8K | — | $0 |
| Mar 1, 2026 | GRAY R BRADLEY | SVP Strategic Development | acquired(A) | 7.7K | — | $0 |
| Mar 1, 2026 | Blair Rainer | President & CEO, Director | acquired(A) | 17.6K | — | $0 |
| Mar 1, 2026 | Blair Rainer | President & CEO, Director | acquired(A) | 47.5K | — | $0 |
| Mar 1, 2026 | Gugino Matthew E | EVP & Chief Financial Officer | acquired(A) | 4.0K | — | $0 |
| Mar 1, 2026 | Gugino Matthew E | EVP & Chief Financial Officer | disposed(F) | 231 | $210.64 | $49K |
| Mar 1, 2026 | Gugino Matthew E | EVP & Chief Financial Officer | acquired(A) | 10.8K | — | $0 |
| Mar 1, 2026 | Sawyer Montgomery Julie A | Executive Vice President | acquired(A) | 6.2K | — | $0 |
| Mar 1, 2026 | Sawyer Montgomery Julie A | Executive Vice President | disposed(F) | 1.1K | $210.64 | $227K |
| Mar 1, 2026 | Sawyer Montgomery Julie A | Executive Vice President | acquired(A) | 16.7K | — | $0 |
| Mar 1, 2026 | Couchara Georgeann | SVP, Human Resources | acquired(A) | 4.7K | — | $0 |
| Mar 1, 2026 | Couchara Georgeann | SVP, Human Resources | disposed(F) | 113 | $210.64 | $24K |
| Mar 1, 2026 | Couchara Georgeann | SVP, Human Resources | acquired(A) | 12.8K | — | $0 |
| Feb 27, 2026 | RALES MITCHELL P | Chairman of Exec. Committee, Director | disposed(G) | 71.6K | — | $0 |
| Feb 24, 2026 | Couchara Georgeann | SVP, Human Resources | disposed(F) | 101 | $209.19 | $21K |
| Feb 24, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | disposed(F) | 344 | $209.19 | $72K |
| Feb 24, 2026 | Bouda Christopher | VP, Chief Accounting Officer | disposed(F) | 235 | $209.19 | $49K |
| Feb 24, 2026 | Milosevich Gregory M | Executive Vice President | disposed(F) | 189 | $209.19 | $40K |
| Feb 24, 2026 | Sawyer Montgomery Julie A | Executive Vice President | disposed(F) | 372 | $209.19 | $78K |
| Feb 24, 2026 | Riley Christopher Paul | Executive Vice President | disposed(F) | 242 | $209.19 | $51K |
| Feb 19, 2026 | Milosevich Gregory M | Executive Vice President | acquired(M) | 1.3K | $58.59 | $77K |
| Feb 19, 2026 | Milosevich Gregory M | Executive Vice President | Sell(S) | 1.3K | $208.01 | $275K |
| Feb 19, 2026 | Milosevich Gregory M | Executive Vice President | disposed(M) | 1.3K | — | $0 |
| Feb 4, 2026 | Riley Christopher Paul | Executive Vice President | acquired(A) | 1.0K | — | $0 |
| Feb 4, 2026 | Ellis Brian W | Senior Vice President | acquired(A) | 1.7K | — | $0 |
| Feb 4, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | acquired(A) | 1.7K | — | $0 |
| Feb 4, 2026 | Couchara Georgeann | SVP, Human Resources | acquired(A) | 1.4K | — | $0 |
| Feb 4, 2026 | Sawyer Montgomery Julie A | Executive Vice President | acquired(A) | 848 | — | $0 |
| Feb 4, 2026 | Blair Rainer | President & CEO, Director | acquired(A) | 8.5K | — | $0 |
| Feb 4, 2026 | McGrew Matthew | EVP & Chief Financial Officer | acquired(A) | 2.7K | — | $0 |
| Feb 4, 2026 | Milosevich Gregory M | Executive Vice President | acquired(A) | 679 | — | $0 |
| Feb 2, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | disposed(F) | 852 | $223.42 | $190K |
| Feb 2, 2026 | Gutierrez-Ramos Jose-Carlos | SVP, Chief Science Officer | acquired(A) | 275 | $218.89 | $60K |
| Feb 2, 2026 | Ellis Brian W | Senior Vice President - GC | disposed(F) | 1.3K | $223.42 | $280K |
| Feb 2, 2026 | Ellis Brian W | Senior Vice President - GC | acquired(A) | 251 | $218.89 | $55K |
| Feb 2, 2026 | Sawyer Montgomery Julie A | Executive Vice President | acquired(A) | 510 | $218.89 | $112K |
| Feb 2, 2026 | Bouda Christopher | VP, Chief Accounting Officer | acquired(A) | 189 | $218.89 | $41K |
| Feb 2, 2026 | McGrew Matthew | EVP & Chief Financial Officer | disposed(F) | 1.9K | $223.42 | $415K |
| Feb 2, 2026 | McGrew Matthew | EVP & Chief Financial Officer | acquired(A) | 790.5 | $228.92 | $181K |
| Feb 2, 2026 | Milosevich Gregory M | Executive Vice President | acquired(A) | 629 | $228.92 | $144K |
| Feb 2, 2026 | GRAY R BRADLEY | SVP Strategic Development | acquired(A) | 212 | $218.89 | $46K |
| Feb 2, 2026 | Leiken Jonathan | SVP-Chief Legal Officer | acquired(A) | 41 | $218.89 | $9K |
| Feb 2, 2026 | Couchara Georgeann | SVP, Human Resources | acquired(A) | 489 | $218.89 | $107K |
| Feb 2, 2026 | Riley Christopher Paul | Executive Vice President | disposed(F) | 640 | $223.42 | $143K |
| Feb 2, 2026 | Riley Christopher Paul | Executive Vice President | acquired(A) | 547 | $218.89 | $120K |
| Feb 2, 2026 | Blair Rainer | President & CEO, Director | disposed(F) | 7.8K | $223.42 | $1.7M |
| Feb 2, 2026 | Blair Rainer | President & CEO, Director | acquired(A) | 1.8K | $228.92 | $420K |
| Feb 2, 2026 | RALES MITCHELL P | Chairman of Exec. Committee, Director | acquired(A) | 79 | $218.89 | $17K |
| Jan 30, 2026 | SPOON ALAN G | Director | acquired(A) | 192.871 | $218.89 | $42K |
| Jan 30, 2026 | Sanders A Shane | Director | acquired(A) | 183.593 | $218.89 | $40K |
| Jan 30, 2026 | List Teri | Director | acquired(A) | 11.157 | $218.89 | $2K |
| Jan 30, 2026 | Zerhouni Elias A. | Director | acquired(A) | 200.506 | $218.89 | $44K |
| Jan 30, 2026 | Dewan Feroz | Director | acquired(A) | 151.195 | $218.89 | $33K |
| Jan 30, 2026 | FILLER LINDA | Director | acquired(A) | 13.016 | $218.89 | $3K |
| Jan 30, 2026 | Stevens Raymond C | Director | acquired(A) | 158.547 | $218.89 | $35K |
| Dec 30, 2025 | RALES MITCHELL P | Chairman of Exec. Committee, Director | acquired(A) | 1.5K | $230.67 | $356K |
| Nov 25, 2025 | RALES MITCHELL P | Chairman of Exec. Committee, Director | Sell(S) | 35.9K | $230.27 | $8.3M |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S) — the tradeable signal; awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).