The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 9, 2023 | RA Capital Healthcare Fund LP | Insider | Tender(U) | 7.1M | — | — |
| Aug 9, 2023 | RA Capital Healthcare Fund LP | Insider | Tender(U) | 786K | — | — |
| Aug 9, 2023 | RA Capital Healthcare Fund LP | Insider | Disposed to issuer(D) | 21K | — | — |
| Aug 9, 2023 | Bowers Lisa | Director | Disposed to issuer(D) | 43K | — | — |
| Aug 9, 2023 | Doyle Mittie | Director | Disposed to issuer(D) | 43K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 147K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 90K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 46K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 11K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 8K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 14K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 4K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 1K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 4K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 1K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 154K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 15K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 4K | — | — |
| Aug 9, 2023 | Jacobsen John R. | CSO | Disposed to issuer(D) | 922 | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 800K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 20K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 17K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 131K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 132K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 385K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 300K | — | — |
| Aug 9, 2023 | Judice Kevin | CEO, Director | Disposed to issuer(D) | 50K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 152K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 26K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 43K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 158K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 90K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 15K | — | — |
| Aug 9, 2023 | Timothy Lu | CMO | Disposed to issuer(D) | 31K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 8K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 9K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 23K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 31K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 4K | — | — |
| Aug 9, 2023 | Scheller Richard H | Director | Disposed to issuer(D) | 8K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 198K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 7K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 771 | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 21K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 3K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 9K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 19K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 15K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 57K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 154K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 113K | — | — |
| Aug 9, 2023 | Robertson Scott M. | CFO & CBO | Disposed to issuer(D) | 17K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 26K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 15K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 12K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 8K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 14K | — | — |
| Aug 9, 2023 | Scopa James Paul | Director | Disposed to issuer(D) | 21K | — | — |
| Aug 9, 2023 | Simson Jake | Director | Disposed to issuer(D) | 21K | — | — |
| Aug 9, 2023 | Tetlow Sharon | Director | Disposed to issuer(D) | 50K | — | — |
| Aug 9, 2023 | Tetlow Sharon | Director | Disposed to issuer(D) | 8K | — | — |
| Aug 9, 2023 | Tetlow Sharon | Director | Disposed to issuer(D) | 21K | — | — |
| Aug 9, 2023 | Tetlow Sharon | Director | Disposed to issuer(D) | 12K | — | — |
| Aug 9, 2023 | Tetlow Sharon | Director | Disposed to issuer(D) | 14K | — | — |
| Aug 2, 2023 | Scopa James Paul | Director | Gift(G) | 2K | — | $0 |
| Aug 2, 2023 | Scopa James Paul | Director | Gift(G) | 220 | — | $0 |
| Jul 18, 2023 | Scopa James Paul | Director | Gift(G) | 2K | — | $0 |
| Jul 11, 2023 | Scopa James Paul | Director | Gift(G) | 300 | — | $0 |
| Jun 22, 2023 | Northpond Ventures II, LP | 10% Owner | Sell(S) | 2.0M | $46.50 | $91.6M |
| Jun 22, 2023 | Northpond Ventures II, LP | 10% Owner | Sell(S) | 524K | $46.50 | $24.3M |
| Jun 1, 2023 | Jacobsen John R. | CSO | Sell(S) | 14K | $30.31 | $434K |
| Jun 1, 2023 | Jacobsen John R. | CSO | Sell(S) | 4K | $31.24 | $139K |
| May 5, 2023 | Scheller Richard H | Director | Sell(S) | 84K | $38.51 | $3.2M |
| May 3, 2023 | Judice Kevin | CEO, Director | Sell(S) | 14K | $36.50 | $500K |
| May 3, 2023 | Timothy Lu | CMO | Sell(S) | 10K | $36.54 | $365K |
| May 3, 2023 | Robertson Scott M. | CFO & CBO | Sell(S) | 19K | $36.55 | $685K |
| May 1, 2023 | Scopa James Paul | Director | Gift(G) | 7K | — | $0 |
| May 1, 2023 | Scopa James Paul | Director | Gift(G) | 7K | — | $0 |
| Apr 18, 2023 | Jacobsen John R. | CSO | Sell(S) | 16K | $30.08 | $493K |
| Mar 31, 2023 | Jacobsen John R. | CSO | Sell(S) | 773 | $30.00 | $23K |
| Mar 30, 2023 | RA Capital Nexus Fund II, L.P. | Director, 10% Owner | Buy(P) | 196K | $28.74 | $5.6M |
| Mar 29, 2023 | RA Capital Nexus Fund II, L.P. | Director, 10% Owner | Buy(P) | 66K | $29.38 | $1.9M |
| Mar 29, 2023 | Jacobsen John R. | CSO | Sell(S) | 1K | $30.00 | $33K |
| Mar 28, 2023 | RA Capital Nexus Fund II, L.P. | Director, 10% Owner | Buy(P) | 247K | $29.24 | $7.2M |
| Mar 28, 2023 | Jacobsen John R. | CSO | Sell(S) | 500 | $30.09 | $15K |
| Mar 27, 2023 | Ra Capital Management, L.P. | Director, 10% Owner | Buy(P) | 151K | $27.48 | $4.2M |
| Mar 24, 2023 | Ra Capital Management, L.P. | Director, 10% Owner | Buy(P) | 192K | $26.87 | $5.2M |
| Mar 23, 2023 | Ra Capital Management, L.P. | Director, 10% Owner | Buy(P) | 155K | $26.67 | $4.1M |
| Mar 17, 2023 | Scopa James Paul | Director | Sell(S) | 10K | $29.05 | $291K |
| Jan 27, 2023 | Jacobsen John R. | CSO | Grant(A) | 90K | — | $0 |
| Jan 27, 2023 | Jacobsen John R. | CSO | Grant(A) | 15K | — | $0 |
| Jan 27, 2023 | Judice Kevin | CEO, Director | Grant(A) | 50K | — | $0 |
| Jan 27, 2023 | Judice Kevin | CEO, Director | Grant(A) | 300K | — | $0 |
| Jan 27, 2023 | Timothy Lu | CMO | Grant(A) | 90K | — | $0 |
| Jan 27, 2023 | Timothy Lu | CMO | Grant(A) | 15K | — | $0 |
| Jan 27, 2023 | Robertson Scott M. | CFO & CBO | Grant(A) | 19K | — | $0 |
| Jan 27, 2023 | Robertson Scott M. | CFO & CBO | Grant(A) | 113K | — | $0 |
| Oct 24, 2022 | Scopa James Paul | Director | Gift(G) | 31K | — | $0 |
| Oct 24, 2022 | Scopa James Paul | Director | Gift(G) | 31K | — | $0 |
| Oct 17, 2022 | Kolchinsky Peter | Director, 10% Owner | Buy(P) | 1.6M | $36.50 | $59.9M |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).