The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 3, 2026 | Baker Bros. Advisors LP | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Baker Bros. Advisors LP | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Baker Bros. Advisors LP | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Baker Bros. Advisors LP | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Flatley Jay T | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Flatley Jay T | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Klein Peter S | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Klein Peter S | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Krognes Steve E. | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Krognes Steve E. | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Schenkein David P | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Schenkein David P | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Thornberry Nancy | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Thornberry Nancy | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Van Hauwermeiren Timothy | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Van Hauwermeiren Timothy | Director | Grant(A) | 19K | — | $0 |
| Jun 3, 2026 | Cook Jennifer E. | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2026 | Cook Jennifer E. | Director | Grant(A) | 19K | — | $0 |
| Jan 6, 2026 | Watts Ryan J. | President and CEO, Director | Sell(S) | 35K | $16.50 | $581K |
| Jan 6, 2026 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 17K | $16.50 | $284K |
| Jan 3, 2026 | Watts Ryan J. | President and CEO, Director | Grant(A) | 79K | — | $0 |
| Jan 3, 2026 | Watts Ryan J. | President and CEO, Director | Grant(A) | 237K | — | $0 |
| Jan 3, 2026 | Schuth Alexander O. | COFO and Secretary | Grant(A) | 58K | — | $0 |
| Jan 3, 2026 | Schuth Alexander O. | COFO and Secretary | Grant(A) | 173K | — | $0 |
| Dec 11, 2025 | Baker Julian | Director | Buy(P) | 2.1M | $17.49 | $36.6M |
| Dec 11, 2025 | Baker Julian | Director | Buy(P) | 191K | $17.49 | $3.3M |
| Nov 4, 2025 | Van Hauwermeiren Timothy | Director | Grant(A) | 11K | — | $0 |
| Nov 4, 2025 | Van Hauwermeiren Timothy | Director | Grant(A) | 32K | — | $0 |
| Sep 3, 2025 | Watts Ryan J. | President and CEO, Director | Gift(G) | 50K | — | $0 |
| Aug 13, 2025 | Ho Carole | Chief Medical Officer | Sell(S) | 806 | $14.64 | $12K |
| Aug 12, 2025 | Ho Carole | Chief Medical Officer | Sell(S) | 3K | $13.58 | $40K |
| Aug 12, 2025 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 3K | $13.58 | $40K |
| Aug 5, 2025 | Ho Carole | Chief Medical Officer | Option exercise(M) | 45K | $0.68 | $30K |
| Aug 5, 2025 | Ho Carole | Chief Medical Officer | Option exercise(M) | 45K | — | $0 |
| Jul 9, 2025 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 40K | $5.28 | $211K |
| Jul 9, 2025 | Watts Ryan J. | President and CEO, Director | Sell(S) | 495K | $15.00 | $7.4M |
| Jul 9, 2025 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 455K | $0.68 | $310K |
| Jul 9, 2025 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 455K | — | $0 |
| Jul 9, 2025 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 40K | — | $0 |
| Jun 3, 2025 | Baker Bros. Advisors LP | Director | Grant(A) | 11K | — | $0 |
| Jun 3, 2025 | Baker Bros. Advisors LP | Director | Grant(A) | 11K | — | $0 |
| Jun 3, 2025 | Baker Bros. Advisors LP | Director | Grant(A) | 32K | — | $0 |
| Jun 3, 2025 | Baker Bros. Advisors LP | Director | Grant(A) | 32K | — | $0 |
| Jun 3, 2025 | Tessier-Lavigne Marc | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Tessier-Lavigne Marc | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Thornberry Nancy | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Thornberry Nancy | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Schenkein David P | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Schenkein David P | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Krognes Steve E. | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Krognes Steve E. | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Klein Peter S | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Klein Peter S | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Flatley Jay T | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Flatley Jay T | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2025 | Cook Jennifer E. | Director | Grant(A) | 6K | — | $0 |
| Jun 3, 2025 | Cook Jennifer E. | Director | Grant(A) | 18K | — | $0 |
| Jan 7, 2025 | Krognes Steve E. | Director | Sell(S) | 3K | $20.81 | $69K |
| Jan 7, 2025 | Watts Ryan J. | President and CEO, Director | Sell(S) | 8K | $20.81 | $159K |
| Jan 7, 2025 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 3K | $20.81 | $60K |
| Jan 7, 2025 | Ho Carole | Chief Medical Officer | Sell(S) | 3K | $20.81 | $60K |
| Jan 6, 2025 | Watts Ryan J. | President and CEO, Director | Sell(S) | 29K | $20.22 | $592K |
| Jan 6, 2025 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 12K | $20.22 | $248K |
| Jan 6, 2025 | Ho Carole | Chief Medical Officer | Sell(S) | 12K | $20.22 | $248K |
| Jan 3, 2025 | Ho Carole | Chief Medical Officer | Grant(A) | 54K | — | $0 |
| Jan 3, 2025 | Ho Carole | Chief Medical Officer | Grant(A) | 163K | — | $0 |
| Jan 3, 2025 | Schuth Alexander O. | COFO and Secretary | Grant(A) | 54K | — | $0 |
| Jan 3, 2025 | Schuth Alexander O. | COFO and Secretary | Grant(A) | 163K | — | $0 |
| Jan 3, 2025 | Watts Ryan J. | President and CEO, Director | Grant(A) | 54K | — | $0 |
| Jan 3, 2025 | Watts Ryan J. | President and CEO, Director | Grant(A) | 163K | — | $0 |
| Jan 2, 2025 | Sato Vicki L | Director | Sell(S) | 3K | $20.91 | $64K |
| Dec 31, 2024 | Krognes Steve E. | Director | Sell(S) | 30K | $20.25 | $608K |
| Dec 27, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 7K | $5.28 | $35K |
| Dec 27, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 7K | — | $0 |
| Nov 25, 2024 | Ho Carole | Chief Medical Officer | Option exercise(M) | 18K | $0.68 | $12K |
| Nov 25, 2024 | Ho Carole | Chief Medical Officer | Option exercise(M) | 18K | — | $0 |
| Nov 22, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 21K | $0.68 | $14K |
| Nov 22, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 21K | — | $0 |
| Nov 11, 2024 | Schenkein David P | Director | Option exercise(M) | 47K | $18.00 | $849K |
| Nov 11, 2024 | Schenkein David P | Director | Sell(S) | 27K | $32.09 | $871K |
| Nov 11, 2024 | Schenkein David P | Director | Sell(S) | 32K | $32.87 | $1.1M |
| Nov 11, 2024 | Schenkein David P | Director | Option exercise(M) | 47K | — | $0 |
| Nov 7, 2024 | Sato Vicki L | Director | Sell(S) | 1K | $30.00 | $31K |
| Nov 7, 2024 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 12K | $29.68 | $366K |
| Nov 7, 2024 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 3K | $30.72 | $90K |
| Nov 7, 2024 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 300 | $31.29 | $9K |
| Nov 7, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 16K | $5.28 | $82K |
| Nov 7, 2024 | Schuth Alexander O. | COFO and Secretary | Option exercise(M) | 16K | — | $0 |
| Nov 1, 2024 | Sato Vicki L | Director | Sell(S) | 3K | $27.07 | $83K |
| Oct 18, 2024 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 40K | $0.68 | $27K |
| Oct 18, 2024 | Watts Ryan J. | President and CEO, Director | Sell(S) | 40K | $27.69 | $1.1M |
| Oct 18, 2024 | Watts Ryan J. | President and CEO, Director | Option exercise(M) | 40K | — | $0 |
| Sep 30, 2024 | Krognes Steve E. | Director | Sell(S) | 30K | $29.03 | $871K |
| Sep 13, 2024 | Sato Vicki L | Director | Sell(S) | 1K | $30.00 | $31K |
| Sep 3, 2024 | Sato Vicki L | Director | Sell(S) | 3K | $24.99 | $74K |
| Sep 3, 2024 | Sato Vicki L | Director | Sell(S) | 100 | $25.37 | $3K |
| Aug 21, 2024 | Ho Carole | Chief Medical Officer | Sell(S) | 14K | $24.41 | $344K |
| Aug 21, 2024 | Ho Carole | Chief Medical Officer | Sell(S) | 6K | $24.96 | $147K |
| Aug 21, 2024 | Schuth Alexander O. | COFO and Secretary | Sell(S) | 3K | $24.78 | $63K |
| Aug 20, 2024 | Ho Carole | Chief Medical Officer | Sell(S) | 2K | $23.79 | $58K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-21. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).