The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Dec 28, 2021 | Koppel Adam | Director | Tender(U) | 3.1M | $38.25 | $117.8M |
| Dec 28, 2021 | Koppel Adam | Director | Tender(U) | 3K | $38.25 | $127K |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Koppel Adam | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Aradhye Shreeram | EVP & Chief Medical Officer | Tender(U) | 7K | $38.25 | $267K |
| Dec 28, 2021 | Aradhye Shreeram | EVP & Chief Medical Officer | Disposed to issuer(D) | 21K | — | — |
| Dec 28, 2021 | Aradhye Shreeram | EVP & Chief Medical Officer | Disposed to issuer(D) | 9K | — | — |
| Dec 28, 2021 | Aradhye Shreeram | EVP & Chief Medical Officer | Disposed to issuer(D) | 51K | — | — |
| Dec 28, 2021 | Aradhye Shreeram | EVP & Chief Medical Officer | Disposed to issuer(D) | 125K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Tender(U) | 2K | $38.25 | $91K |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 85K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 11K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 26K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 180K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 165K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 121K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 68K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 105K | — | — |
| Dec 28, 2021 | Brown Bob D | Chief Scientific Ofr., EVP R&D | Disposed to issuer(D) | 75K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Tender(U) | 5K | $38.25 | $178K |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 21K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 33K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Buchi J Kevin | Director | Disposed to issuer(D) | 8K | — | — |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Tender(U) | 15K | $38.25 | $567K |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Disposed to issuer(D) | 10K | — | — |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Disposed to issuer(D) | 17K | — | — |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Disposed to issuer(D) | 62K | — | — |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Disposed to issuer(D) | 76K | — | — |
| Dec 28, 2021 | Ciappenelli Robert D. | Chief Strategy Officer | Disposed to issuer(D) | 270K | — | — |
| Dec 28, 2021 | Doberstein Stephen K | Director | Tender(U) | 3K | $38.25 | $127K |
| Dec 28, 2021 | Doberstein Stephen K | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Doberstein Stephen K | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Doberstein Stephen K | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Doberstein Stephen K | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 231K | $38.25 | $8.9M |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 60K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 41K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 191K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 281K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 55K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 225K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 255K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 505K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 72K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 200K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 200K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 225K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 250K | — | — |
| Dec 28, 2021 | Fambrough Douglas | Chief Executive Officer, Director | Disposed to issuer(D) | 248K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Tender(U) | 3K | $38.25 | $127K |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Freed Martin I | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Gray Patrick M. | Director | Tender(U) | 3K | $38.25 | $127K |
| Dec 28, 2021 | Gray Patrick M. | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Gray Patrick M. | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Gray Patrick M. | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Gray Patrick M. | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Tender(U) | 16K | $38.25 | $618K |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Hoffman Stephen J | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 5K | $38.25 | $191K |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 6K | $38.25 | $242K |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Kozin Marc D | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Pagan Douglas W. | Chief Financial Officer | Tender(U) | 8K | $38.25 | $297K |
| Dec 28, 2021 | Pagan Douglas W. | Chief Financial Officer | Disposed to issuer(D) | 6K | — | — |
| Dec 28, 2021 | Pagan Douglas W. | Chief Financial Officer | Disposed to issuer(D) | 20K | — | — |
| Dec 28, 2021 | Pagan Douglas W. | Chief Financial Officer | Disposed to issuer(D) | 37K | — | — |
| Dec 28, 2021 | Pagan Douglas W. | Chief Financial Officer | Disposed to issuer(D) | 96K | — | — |
| Dec 28, 2021 | Smith Cynthia | Director | Tender(U) | 3K | $38.25 | $127K |
| Dec 28, 2021 | Smith Cynthia | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Smith Cynthia | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Smith Cynthia | Director | Disposed to issuer(D) | 15K | — | — |
| Dec 28, 2021 | Smith Cynthia | Director | Disposed to issuer(D) | 25K | — | — |
| Dec 28, 2021 | Smith Cynthia | Director | Disposed to issuer(D) | 3K | — | — |
| Dec 28, 2021 | Weissman James B | Chief Operating Officer & EVP | Tender(U) | 18K | $38.25 | $692K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-11. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).