The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 191K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 237K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 318K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 350K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 375K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Disposed to issuer(D) | 1.3M | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 180K | — | — |
| Feb 19, 2024 | Veneman Ann M | Insider | Disposed to issuer(D) | 3K | — | — |
| Feb 19, 2024 | Veneman Ann M | Insider | Tender(U) | 11K | — | — |
| Feb 19, 2024 | Veneman Ann M | Insider | Disposed to issuer(D) | 22K | — | — |
| Feb 19, 2024 | Veneman Ann M | Insider | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | Veneman Ann M | Insider | Disposed to issuer(D) | 26K | — | — |
| Feb 19, 2024 | Khan Amin | Insider | Disposed to issuer(D) | 180K | — | — |
| Feb 19, 2024 | Khan Amin | Insider | Disposed to issuer(D) | 120K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Tender(U) | 359K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Tender(U) | 525K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Tender(U) | 129K | — | — |
| Feb 19, 2024 | Simpson Adam K. | Insider | Tender(U) | 129K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Tender(U) | 224K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 42K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 83K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 3K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 108K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 110K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 119K | — | — |
| Feb 19, 2024 | Kanesa-thasan Niranjan | Insider | Disposed to issuer(D) | 82K | — | — |
| Feb 19, 2024 | McDade Mark | Insider | Tender(U) | 56K | — | — |
| Feb 19, 2024 | McDade Mark | Insider | Tender(U) | 3.5M | — | — |
| Feb 19, 2024 | McDade Mark | Insider | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | McDade Mark | Insider | Disposed to issuer(D) | 22K | — | — |
| Feb 19, 2024 | Shiver John W. | Insider | Tender(U) | 8K | — | — |
| Feb 19, 2024 | Shiver John W. | Insider | Disposed to issuer(D) | 3K | — | — |
| Feb 19, 2024 | Shiver John W. | Insider | Disposed to issuer(D) | 10K | — | — |
| Feb 19, 2024 | Shiver John W. | Insider | Disposed to issuer(D) | 26K | — | — |
| Feb 19, 2024 | Shiver John W. | Insider | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Tender(U) | 39K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Disposed to issuer(D) | 75K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Disposed to issuer(D) | 377K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Disposed to issuer(D) | 125K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Disposed to issuer(D) | 98K | — | — |
| Feb 19, 2024 | Russo Thomas Joseph | Insider | Disposed to issuer(D) | 100K | — | — |
| Feb 19, 2024 | Wassil Jim | Insider | Tender(U) | 4K | — | — |
| Feb 19, 2024 | Wassil Jim | Insider | Disposed to issuer(D) | 7K | — | — |
| Feb 19, 2024 | Wassil Jim | Insider | Disposed to issuer(D) | 45K | — | — |
| Feb 19, 2024 | Wassil Jim | Insider | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | Fields Heidi | Insider | Disposed to issuer(D) | 3K | — | — |
| Feb 19, 2024 | Fields Heidi | Insider | Tender(U) | 11K | — | — |
| Feb 19, 2024 | Fields Heidi | Insider | Disposed to issuer(D) | 22K | — | — |
| Feb 19, 2024 | Fields Heidi | Insider | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | Fields Heidi | Insider | Disposed to issuer(D) | 25K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Tender(U) | 132K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 140K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 104K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 100K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 3K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 89K | — | — |
| Feb 19, 2024 | Cearley Cassia | Insider | Disposed to issuer(D) | 83K | — | — |
| Feb 19, 2024 | RA Capital Healthcare Fund LP | Director, 10% Owner | Tender(U) | 639K | — | — |
| Feb 19, 2024 | RA Capital Healthcare Fund LP | Director, 10% Owner | Tender(U) | 5.3M | — | — |
| Feb 19, 2024 | RA Capital Healthcare Fund LP | Director, 10% Owner | Tender(U) | 6K | — | — |
| Feb 19, 2024 | RA Capital Healthcare Fund LP | Director, 10% Owner | Disposed to issuer(D) | 17K | — | — |
| Feb 19, 2024 | RA Capital Healthcare Fund LP | Director, 10% Owner | Disposed to issuer(D) | 22K | — | — |
| Feb 1, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 15K | $15.29 | $229K |
| Feb 1, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Gift(G) | 7K | — | $0 |
| Feb 1, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 15K | $1.04 | $16K |
| Feb 1, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 15K | — | $0 |
| Jan 22, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 5K | $0.84 | $4K |
| Jan 22, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 93K | $1.04 | $97K |
| Jan 22, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 93K | — | $0 |
| Jan 22, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 5K | — | $0 |
| Jan 2, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 15K | $15.67 | $235K |
| Jan 2, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 15K | $1.04 | $16K |
| Jan 2, 2024 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 15K | — | $0 |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 50K | $15.44 | $772K |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 40K | $15.43 | $617K |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 23K | $0.84 | $20K |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 40K | $2.47 | $99K |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 103K | $1.04 | $107K |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 23K | — | $0 |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 40K | — | $0 |
| Dec 21, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 103K | — | $0 |
| Dec 20, 2023 | Cearley Cassia | Chief Business Officer | Sell(S) | 8K | $15.46 | $123K |
| Dec 20, 2023 | Kanesa-thasan Niranjan | Chief Medical Officer | Sell(S) | 12K | $15.46 | $184K |
| Dec 20, 2023 | Russo Thomas Joseph | Chief Financial Officer | Sell(S) | 4K | $15.47 | $69K |
| Dec 20, 2023 | Russo Thomas Joseph | Chief Financial Officer | Sell(S) | 11K | $15.46 | $166K |
| Dec 20, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 62K | $15.46 | $962K |
| Dec 13, 2023 | Cearley Cassia | Chief Business Officer | Sell(S) | 9K | $16.01 | $140K |
| Aug 1, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 3K | $0.84 | $3K |
| Aug 1, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Option exercise(M) | 3K | — | $0 |
| Jul 31, 2023 | Cearley Cassia | Chief Business Officer | Sell(S) | 2K | $8.86 | $17K |
| Jul 31, 2023 | Russo Thomas Joseph | Chief Financial Officer | Sell(S) | 3K | $8.86 | $27K |
| Jul 31, 2023 | Simpson Adam K. | Chief Executive Officer, Director | Sell(S) | 12K | $8.86 | $104K |
| Jul 31, 2023 | Kanesa-thasan Niranjan | Chief Medical Officer | Sell(S) | 3K | $8.86 | $29K |
| Jul 3, 2023 | Holtzman Douglas | Chief Scientific Officer | Sell(S) | 2K | $9.59 | $20K |
| Jul 3, 2023 | Holtzman Douglas | Chief Scientific Officer | Sell(S) | 14K | $8.74 | $125K |
| Jul 3, 2023 | Holtzman Douglas | Chief Scientific Officer | Option exercise(M) | 16K | $1.04 | $17K |
| Jul 3, 2023 | Holtzman Douglas | Chief Scientific Officer | Option exercise(M) | 16K | — | $0 |
| Jun 12, 2023 | Khan Amin | EVP, Head of Research & Dev. | Grant(A) | 180K | — | $0 |
| Jun 6, 2023 | Kolchinsky Peter | Director, 10% Owner | Grant(A) | 17K | — | $0 |
| Jun 6, 2023 | Fields Heidi | Director | Grant(A) | 17K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).