The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | Tender(U) | 46K | — | — |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | Disposed to issuer(D) | 16K | — | — |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | Disposed to issuer(D) | 69K | — | — |
| Aug 29, 2025 | McGrath Yvonne | Chief Scientific Officer | Disposed to issuer(D) | 91K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Tender(U) | 89K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Disposed to issuer(D) | 9K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Disposed to issuer(D) | 252K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Disposed to issuer(D) | 8K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Disposed to issuer(D) | 42K | — | — |
| Aug 29, 2025 | Gall Matthew | Chief Financial Officer | Disposed to issuer(D) | 136K | — | — |
| Aug 29, 2025 | Feltquate David | Chief Medical Officer | Tender(U) | 47K | — | — |
| Aug 29, 2025 | Lee David K | Director | Disposed to issuer(D) | 24K | — | — |
| Aug 29, 2025 | Lee David K | Director | Disposed to issuer(D) | 21K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Tender(U) | 94K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Tender(U) | 154K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 18K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 185K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 53K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 50K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 94K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 445K | — | — |
| Aug 29, 2025 | Detheux Michel | Chief Executive Officer, Director | Disposed to issuer(D) | 14K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Tender(U) | 162K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 147K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 17K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 42K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 66K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 136K | — | — |
| Aug 29, 2025 | Call Matthew | Chief Operating Officer | Disposed to issuer(D) | 9K | — | — |
| Aug 29, 2025 | Rhoads Ann D | Director | Disposed to issuer(D) | 27K | — | — |
| Aug 29, 2025 | Hallal David | Director | Disposed to issuer(D) | 146K | — | — |
| Aug 29, 2025 | Hallal David | Director | Disposed to issuer(D) | 25K | — | — |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | $4.30 | $189K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | $4.30 | $36K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 8K | $10.02 | $84K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 94K | $4.30 | $404K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 18K | $4.30 | $77K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 44K | $10.02 | $440K |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | — | $0 |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 18K | — | $0 |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 94K | — | $0 |
| Jun 10, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | — | $0 |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | $4.30 | $36K |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 8K | $10.03 | $84K |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | $4.30 | $189K |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 44K | $10.03 | $440K |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | — | $0 |
| Jun 9, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | — | $0 |
| Jun 6, 2025 | Hallal David | Director | Option exercise(M) | 38K | $4.30 | $164K |
| Jun 6, 2025 | Hallal David | Director | Sell(S) | 38K | $10.24 | $391K |
| Jun 6, 2025 | Hallal David | Director | Option exercise(M) | 38K | — | $0 |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 44K | $10.21 | $448K |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | $4.30 | $189K |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 8K | $10.21 | $86K |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | $4.30 | $36K |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | — | $0 |
| Jun 6, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | — | $0 |
| Jun 5, 2025 | Hallal David | Director | Option exercise(M) | 38K | $4.30 | $164K |
| Jun 5, 2025 | Hallal David | Director | Sell(S) | 38K | $10.15 | $388K |
| Jun 5, 2025 | Hallal David | Director | Option exercise(M) | 38K | — | $0 |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | $4.30 | $36K |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 8K | $10.15 | $85K |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | $4.30 | $189K |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 44K | $10.15 | $445K |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | — | $0 |
| Jun 5, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | — | $0 |
| Jun 4, 2025 | Hallal David | Director | Option exercise(M) | 38K | $4.30 | $164K |
| Jun 4, 2025 | Hallal David | Director | Sell(S) | 38K | $10.07 | $385K |
| Jun 4, 2025 | Hallal David | Director | Option exercise(M) | 38K | — | $0 |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | $4.30 | $36K |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 8K | $10.10 | $85K |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | $4.30 | $189K |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Sell(S) | 44K | $10.10 | $443K |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 44K | — | $0 |
| Jun 4, 2025 | Detheux Michel | Chief Executive Officer | Option exercise(M) | 8K | — | $0 |
| May 15, 2025 | EcoR1 Capital, LLC | 10% Owner | Buy(P) | 3.3M | $8.00 | $26.4M |
| May 14, 2025 | EcoR1 Capital, LLC | 10% Owner | Buy(P) | 1.7M | $7.41 | $12.3M |
| May 13, 2025 | Van Hauwermeiren Timothy | Director | Option exercise(M) | 22K | $4.30 | $96K |
| May 13, 2025 | Van Hauwermeiren Timothy | Director | Option exercise(M) | 22K | — | $0 |
| May 13, 2025 | MPM Bioventures 2018 (B), L.P. | Insider | Sell(S) | 630K | $8.06 | $5.1M |
| May 13, 2025 | MPM BioVentures 2018 GP LLC | Insider | Sell(S) | 630K | $8.06 | $5.1M |
| May 13, 2025 | MPM BioImpact LLC | Insider | Sell(S) | 1.0M | $8.06 | $8.3M |
| Mar 7, 2025 | Gall Matthew | Chief Financial Officer | Grant(A) | 24K | — | $0 |
| Mar 7, 2025 | Gall Matthew | Chief Financial Officer | Grant(A) | 145K | — | $0 |
| Mar 7, 2025 | McGrath Yvonne | Chief Scientific Officer | Grant(A) | 15K | — | $0 |
| Mar 7, 2025 | McGrath Yvonne | Chief Scientific Officer | Grant(A) | 91K | — | $0 |
| Mar 7, 2025 | Detheux Michel | Chief Executive Officer | Grant(A) | 77K | — | $0 |
| Mar 7, 2025 | Detheux Michel | Chief Executive Officer | Grant(A) | 459K | — | $0 |
| Mar 7, 2025 | Call Matthew | Chief Operating Officer | Grant(A) | 24K | — | $0 |
| Mar 7, 2025 | Call Matthew | Chief Operating Officer | Grant(A) | 145K | — | $0 |
| Dec 6, 2024 | Feltquate David | Chief Medical Officer | Grant(A) | 47K | — | $0 |
| Nov 19, 2024 | Gall Matthew | Chief Financial Officer | Buy(P) | 5K | $7.73 | $39K |
| Aug 8, 2024 | Detheux Michel | Chief Executive Officer | Gift(G) | 443K | — | $0 |
| Aug 8, 2024 | Detheux Michel | Chief Executive Officer | Gift(G) | 443K | — | $0 |
| Aug 1, 2024 | Feltquate David | Chief Medical Officer | Grant(A) | 350K | — | $0 |
| Jun 11, 2024 | Iannone Robert | Director | Grant(A) | 24K | — | $0 |
| Jun 11, 2024 | Rhoads Ann D | Director | Grant(A) | 24K | — | $0 |
| Jun 11, 2024 | DeSimone Jill | Director | Grant(A) | 24K | — | $0 |
| Jun 11, 2024 | Hallal David | Director | Grant(A) | 24K | — | $0 |
| Jun 11, 2024 | Davis Aaron I. | Director | Grant(A) | 24K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).