The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 85K | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 450K | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 1.4M | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 41K | — | — |
| Apr 3, 2024 | OrbiMed Asia GP IV, L.P. | Director, 10% Owner | Disposed to issuer(D) | 4.7M | — | — |
| Apr 3, 2024 | OrbiMed Asia GP IV, L.P. | Director, 10% Owner | Disposed to issuer(D) | 1.4M | — | — |
| Apr 3, 2024 | OrbiMed Asia GP IV, L.P. | Director, 10% Owner | Disposed to issuer(D) | 1.4M | — | — |
| Apr 3, 2024 | OrbiMed Asia GP IV, L.P. | Director, 10% Owner | Disposed to issuer(D) | 450K | — | — |
| Apr 3, 2024 | OrbiMed Asia GP IV, L.P. | Director, 10% Owner | Disposed to issuer(D) | 85K | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 4.7M | — | — |
| Apr 3, 2024 | Gordon Carl L | Director, 10% Owner | Disposed to issuer(D) | 1.4M | — | — |
| Apr 3, 2024 | Foresite Capital Opportunity Fund V, L.P. | 10% Owner | Disposed to issuer(D) | 3.5M | — | — |
| Apr 3, 2024 | Foresite Capital Opportunity Fund V, L.P. | 10% Owner | Disposed to issuer(D) | 521K | — | — |
| Apr 3, 2024 | Foresite Capital Opportunity Fund V, L.P. | 10% Owner | Disposed to issuer(D) | 9.7M | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 28K | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 100K | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 385K | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 135K | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 215K | — | — |
| Apr 3, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Disposed to issuer(D) | 122K | — | — |
| Apr 3, 2024 | DeSimone Jill | Director | Disposed to issuer(D) | 50K | — | — |
| Apr 3, 2024 | Sabzevari Helen | Director | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Sabzevari Helen | Director | Disposed to issuer(D) | 41K | — | — |
| Apr 3, 2024 | Sabzevari Helen | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Rome Michael E | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Rome Michael E | Director | Disposed to issuer(D) | 41K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 66K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 32K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 56K | — | — |
| Apr 3, 2024 | Flaherty Keith T. | Director | Disposed to issuer(D) | 11K | — | — |
| Apr 3, 2024 | Epperly Melissa B, | Director | Disposed to issuer(D) | 61K | — | — |
| Apr 3, 2024 | Epperly Melissa B, | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Epperly Melissa B, | Director | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Epperly Melissa B, | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Smaldone Alsup Laurie | Director | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Smaldone Alsup Laurie | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Smaldone Alsup Laurie | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Smaldone Alsup Laurie | Director | Disposed to issuer(D) | 61K | — | — |
| Apr 3, 2024 | Krishnamohan Neha | CHIEF FINANCIAL OFFICER | Disposed to issuer(D) | 64K | — | — |
| Apr 3, 2024 | Krishnamohan Neha | CHIEF FINANCIAL OFFICER | Disposed to issuer(D) | 270K | — | — |
| Apr 3, 2024 | Krishnamohan Neha | CHIEF FINANCIAL OFFICER | Disposed to issuer(D) | 215K | — | — |
| Apr 3, 2024 | Krishnamohan Neha | CHIEF FINANCIAL OFFICER | Disposed to issuer(D) | 185K | — | — |
| Apr 3, 2024 | Mitchell Dean J | Director | Disposed to issuer(D) | 25K | — | — |
| Apr 3, 2024 | Mitchell Dean J | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Mitchell Dean J | Director | Disposed to issuer(D) | 20K | — | — |
| Apr 3, 2024 | Mitchell Dean J | Director | Disposed to issuer(D) | 122K | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 2K | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 437K | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 1.3M | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 750K | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 275K | — | — |
| Apr 3, 2024 | Farzan Nima | CHIEF EXECUTIVE OFFICER, Director | Disposed to issuer(D) | 400K | — | — |
| Apr 3, 2024 | Tananbaum James B. | Director, 10% Owner | Disposed to issuer(D) | 521K | — | — |
| Apr 3, 2024 | Tananbaum James B. | Director, 10% Owner | Disposed to issuer(D) | 3.5M | — | — |
| Apr 3, 2024 | Tananbaum James B. | Director, 10% Owner | Disposed to issuer(D) | 9.7M | — | — |
| Apr 3, 2024 | Tananbaum James B. | Director, 10% Owner | Disposed to issuer(D) | 41K | — | — |
| Apr 3, 2024 | Tananbaum James B. | Director, 10% Owner | Disposed to issuer(D) | 20K | — | — |
| Mar 1, 2024 | Meltz Mark A | COO GENERAL COUNSEL SECRETARY | Tax withholding(F) | 558 | $2.59 | $1K |
| Mar 1, 2024 | Williams Richard Thomas | CHIEF MEDICAL OFFICER | Tax withholding(F) | 558 | $2.59 | $1K |
| Mar 1, 2024 | Krishnamohan Neha | CHIEF FINANCIAL OFFICER | Tax withholding(F) | 2K | $2.59 | $4K |
| Dec 1, 2023 | Meltz Mark A | COO General Counsel Secretary | Tax withholding(F) | 541 | $2.25 | $1K |
| Dec 1, 2023 | Krishnamohan Neha | Chief Financial Officer | Tax withholding(F) | 1K | $2.25 | $3K |
| Dec 1, 2023 | Williams Richard Thomas | Chief Medical Officer | Tax withholding(F) | 541 | $2.25 | $1K |
| Sep 1, 2023 | Williams Richard Thomas | Chief Medical Officer | Tax withholding(F) | 541 | $2.35 | $1K |
| Sep 1, 2023 | Meltz Mark A | COO General Counsel Secretary | Tax withholding(F) | 541 | $2.35 | $1K |
| Sep 1, 2023 | Krishnamohan Neha | Chief Financial Officer | Tax withholding(F) | 1K | $2.35 | $3K |
| Jun 12, 2023 | Epperly Melissa B, | Director | Grant(A) | 25K | — | $0 |
| Jun 12, 2023 | Flaherty Keith T. | Director | Grant(A) | 25K | — | $0 |
| Jun 12, 2023 | Gordon Carl L | Director, 10% Owner | Grant(A) | 25K | — | $0 |
| Jun 12, 2023 | Mitchell Dean J | Director | Grant(A) | 25K | — | $0 |
| Jun 12, 2023 | Smaldone Alsup Laurie | Director | Grant(A) | 25K | — | $0 |
| Jun 12, 2023 | Sabzevari Helen | Director | Grant(A) | 25K | — | $0 |
| Jun 1, 2023 | Meltz Mark A | COO General Counsel Secretary | Tax withholding(F) | 541 | $4.30 | $2K |
| Jun 1, 2023 | Williams Richard Thomas | Chief Medical Officer | Tax withholding(F) | 541 | $4.30 | $2K |
| Jun 1, 2023 | Krishnamohan Neha | Chief Financial Officer | Tax withholding(F) | 1K | $4.30 | $6K |
| May 8, 2023 | Foresite Capital Management IV, LLC | 10% Owner | Buy(P) | 1.6M | $2.80 | $4.3M |
| May 8, 2023 | Foresite Capital Management IV, LLC | 10% Owner | Buy(P) | 229K | $2.80 | $641K |
| May 8, 2023 | Tananbaum James B. | Director, 10% Owner | Buy(P) | 229K | $2.80 | $641K |
| May 8, 2023 | Tananbaum James B. | Director, 10% Owner | Buy(P) | 1.6M | $2.80 | $4.3M |
| May 5, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 491K | $2.82 | $1.4M |
| May 5, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 491K | $2.82 | $1.4M |
| May 5, 2023 | Orbimed Advisors LLC | Director, 10% Owner | Buy(P) | 491K | $2.82 | $1.4M |
| May 5, 2023 | Orbimed Advisors LLC | Director, 10% Owner | Buy(P) | 491K | $2.82 | $1.4M |
| May 4, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 313K | $2.75 | $861K |
| May 4, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 83K | $2.75 | $230K |
| May 4, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 83K | $2.75 | $230K |
| May 4, 2023 | Orbimed Advisors LLC | Director, 10% Owner | Buy(P) | 83K | $2.75 | $230K |
| May 4, 2023 | Orbimed Advisors LLC | Director, 10% Owner | Buy(P) | 83K | $2.75 | $230K |
| May 4, 2023 | Orbimed Advisors LLC | Director, 10% Owner | Buy(P) | 313K | $2.75 | $861K |
| May 2, 2023 | OrbiMed Capital GP VII LLC | Director, 10% Owner | Buy(P) | 59K | $2.67 | $157K |
| May 2, 2023 | OrbiMed Capital GP VII LLC | Director, 10% Owner | Buy(P) | 221K | $2.67 | $589K |
| May 2, 2023 | OrbiMed Capital GP VII LLC | Director, 10% Owner | Buy(P) | 59K | $2.67 | $157K |
| May 2, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 59K | $2.67 | $157K |
| May 2, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 221K | $2.67 | $589K |
| May 2, 2023 | Gordon Carl L | Director, 10% Owner | Buy(P) | 59K | $2.67 | $157K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).