The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 1, 2026 | Bradsher Neal C | Director, 10% Owner | Grant(A) | 125K | — | $0 |
| Jul 1, 2026 | Andrews Deborah J | Director | Grant(A) | 125K | — | $0 |
| Jul 1, 2026 | Amin Dipti | Director | Grant(A) | 125K | — | $0 |
| Jul 1, 2026 | Jayasuriya Anula | Director | Grant(A) | 125K | — | $0 |
| Jul 1, 2026 | Russell Angus C. | Director | Grant(A) | 125K | — | $0 |
| Jul 1, 2026 | Mulroy Michael H. | Director | Grant(A) | 125K | — | $0 |
| Mar 12, 2026 | Culley Brian M | President and CEO, Director | Buy(P) | 15K | $1.63 | $24K |
| Mar 5, 2026 | Samuel George A. III | General Counsel and Secretary | Grant(A) | 900K | — | $0 |
| Mar 5, 2026 | Howe Jill Ann | Chief Financial Officer | Grant(A) | 1.1M | — | $0 |
| Mar 5, 2026 | Culley Brian M | President and CEO, Director | Grant(A) | 3.3M | — | $0 |
| Feb 11, 2026 | Samuel George A. III | General Counsel and Secretary | Option exercise(M) | 6K | — | — |
| Feb 11, 2026 | Samuel George A. III | General Counsel and Secretary | Tax withholding(F) | 3K | $1.80 | $5K |
| Feb 11, 2026 | Samuel George A. III | General Counsel and Secretary | Option exercise(M) | 6K | — | $0 |
| Feb 11, 2026 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | — |
| Feb 11, 2026 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 13K | $1.80 | $23K |
| Feb 11, 2026 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | $0 |
| Dec 19, 2025 | Samuel George A. III | General Counsel and Secretary | Grant(A) | 2K | — | — |
| Dec 19, 2025 | Samuel George A. III | General Counsel and Secretary | Tax withholding(F) | 65 | $1.68 | $109 |
| Dec 19, 2025 | Culley Brian M | President and CEO, Director | Grant(A) | 9K | — | — |
| Dec 19, 2025 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 334 | $1.68 | $561 |
| Jul 1, 2025 | Bradsher Neal C | Director, 10% Owner | Grant(A) | 75K | — | $0 |
| Jul 1, 2025 | Andrews Deborah J | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2025 | Mulroy Michael H. | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2025 | Russell Angus C. | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2025 | Jayasuriya Anula | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2025 | Amin Dipti | Director | Grant(A) | 75K | — | $0 |
| Mar 10, 2025 | Samuel George A. III | General Counsel and Secretary | Grant(A) | 750K | — | $0 |
| Mar 10, 2025 | Howe Jill Ann | Chief Financial Officer | Grant(A) | 750K | — | $0 |
| Mar 10, 2025 | Culley Brian M | President and CEO, Director | Grant(A) | 2.3M | — | $0 |
| Feb 11, 2025 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | — |
| Feb 11, 2025 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 13K | $0.65 | $8K |
| Feb 11, 2025 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | $0 |
| Feb 11, 2025 | Samuel George A. III | General Counsel | Option exercise(M) | 6K | — | — |
| Feb 11, 2025 | Samuel George A. III | General Counsel | Tax withholding(F) | 2K | $0.65 | $2K |
| Feb 11, 2025 | Samuel George A. III | General Counsel | Option exercise(M) | 6K | — | $0 |
| Jan 27, 2025 | Broadwood Capital Inc | 10% Owner | Buy(P) | 7.9M | $0.76 | $6.0M |
| Jan 27, 2025 | Broadwood Capital Inc | 10% Owner | Buy(P) | 0 | — | $0 |
| Jan 27, 2025 | Broadwood Capital Inc | 10% Owner | Buy(P) | 7.9M | — | $0 |
| Jan 27, 2025 | Broadwood Capital Inc | 10% Owner | Buy(P) | 0 | — | $0 |
| Nov 26, 2024 | Samuel George A. III | General Counsel | Buy(P) | 15K | $0.60 | $9K |
| Nov 26, 2024 | Howe Jill Ann | Chief Financial Officer | Buy(P) | 15K | $0.59 | $9K |
| Nov 22, 2024 | Mulroy Michael H. | Director | Buy(P) | 40K | $0.57 | $23K |
| Nov 21, 2024 | Culley Brian M | President and CEO, Director | Buy(P) | 40K | $0.60 | $24K |
| Aug 16, 2024 | Howe Jill Ann | Chief Financial Officer | Buy(P) | 11K | $0.89 | $9K |
| Jul 1, 2024 | Bradsher Neal C | Director, 10% Owner | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Andrews Deborah J | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Amin Dipti | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Jayasuriya Anula | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Bailey Don M | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Russell Angus C. | Director | Grant(A) | 75K | — | $0 |
| Jul 1, 2024 | Mulroy Michael H. | Director | Grant(A) | 75K | — | $0 |
| May 24, 2024 | Culley Brian M | President and CEO, Director | Buy(P) | 10K | $1.05 | $11K |
| Mar 7, 2024 | Howe Jill Ann | Chief Financial Officer | Grant(A) | 650K | — | $0 |
| Mar 7, 2024 | Culley Brian M | President and CEO, Director | Grant(A) | 1.9M | — | $0 |
| Mar 7, 2024 | Samuel George A. III | General Counsel/Secretary | Grant(A) | 650K | — | $0 |
| Feb 11, 2024 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | — |
| Feb 11, 2024 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 13K | $1.08 | $14K |
| Feb 11, 2024 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | $0 |
| Feb 11, 2024 | Samuel George A. III | General Counsel/Secretary | Option exercise(M) | 6K | — | — |
| Feb 11, 2024 | Samuel George A. III | General Counsel/Secretary | Tax withholding(F) | 2K | $1.08 | $3K |
| Feb 11, 2024 | Samuel George A. III | General Counsel/Secretary | Option exercise(M) | 6K | — | $0 |
| Feb 8, 2024 | Bailey Don M | Director | Buy(P) | 96K | $1.04 | $100K |
| Feb 6, 2024 | Broadwood Partners, L.P. | Director, 10% Owner | Buy(P) | 0 | — | $0 |
| Feb 6, 2024 | Broadwood Partners, L.P. | Director, 10% Owner | Buy(P) | 6.7M | $1.04 | $7.0M |
| Dec 29, 2023 | Jayasuriya Anula | Director | Buy(P) | 10K | $1.09 | $11K |
| Jul 1, 2023 | Bradsher Neal C | Director, 10% Owner | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Amin Dipti | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Andrews Deborah J | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Bailey Don M | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Jayasuriya Anula | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Kingsley Alfred D | Chairman, Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Mulroy Michael H. | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2023 | Russell Angus C. | Director | Grant(A) | 50K | — | $0 |
| Mar 9, 2023 | Howe Jill Ann | Chief Financial Officer | Grant(A) | 150K | — | $0 |
| Mar 9, 2023 | Culley Brian M | President and CEO, Director | Grant(A) | 1.9M | — | $0 |
| Mar 9, 2023 | Samuel George A. III | General Counsel/Secretary | Grant(A) | 650K | — | $0 |
| Mar 9, 2023 | Hogge Gary S. | SVP,Clinical & Medical Affairs | Grant(A) | 400K | — | $0 |
| Feb 11, 2023 | Hogge Gary S. | SVP,Clinical & Medical Affairs | Option exercise(M) | 13K | — | — |
| Feb 11, 2023 | Hogge Gary S. | SVP,Clinical & Medical Affairs | Tax withholding(F) | 5K | $1.35 | $7K |
| Feb 11, 2023 | Hogge Gary S. | SVP,Clinical & Medical Affairs | Option exercise(M) | 13K | — | $0 |
| Feb 11, 2023 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | — |
| Feb 11, 2023 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 13K | $1.35 | $17K |
| Feb 11, 2023 | Culley Brian M | President and CEO, Director | Option exercise(M) | 31K | — | $0 |
| Feb 11, 2023 | Samuel George A. III | General Counsel/Secretary | Option exercise(M) | 6K | — | — |
| Feb 11, 2023 | Samuel George A. III | General Counsel/Secretary | Tax withholding(F) | 2K | $1.35 | $3K |
| Feb 11, 2023 | Samuel George A. III | General Counsel/Secretary | Option exercise(M) | 6K | — | $0 |
| Nov 14, 2022 | Howe Jill Ann | Chief Financial Officer | Grant(A) | 1.0M | — | $0 |
| Jul 1, 2022 | Bradsher Neal C | Director, 10% Owner | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Bailey Don M | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Kingsley Alfred D | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Mulroy Michael H. | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Jayasuriya Anula | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Andrews Deborah J | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Russell Angus C. | Director | Grant(A) | 50K | — | $0 |
| Jul 1, 2022 | Amin Dipti | Director | Grant(A) | 50K | — | $0 |
| Jun 30, 2022 | Culley Brian M | President and CEO, Director | Option exercise(M) | 15K | — | — |
| Jun 30, 2022 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 5K | $1.58 | $8K |
| Jun 30, 2022 | Culley Brian M | President and CEO, Director | Option exercise(M) | 15K | — | $0 |
| Mar 31, 2022 | Culley Brian M | President and CEO, Director | Buy(P) | 6K | $1.53 | $10K |
| Mar 31, 2022 | Culley Brian M | President and CEO, Director | Tax withholding(F) | 5K | $1.54 | $8K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-11. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).