The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Feb 8, 2023 | TRV GP IV, LLC | 10% Owner | Sell(S) | 1.5M | $0.82 | $1.2M |
| Feb 7, 2023 | TRV GP IV, LLC | 10% Owner | Sell(S) | 2.2M | $0.83 | $1.8M |
| Nov 30, 2022 | Stants Kristen | Chief People Officer | Grant(A) | 3K | $0.94 | $3K |
| Nov 30, 2022 | Gardner Jason | See Remarks, Director | Grant(A) | 3K | $0.94 | $3K |
| Nov 30, 2022 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 3K | $0.94 | $3K |
| Nov 30, 2022 | Mahoney Stephen F. | See Remarks | Grant(A) | 3K | $0.94 | $3K |
| Nov 30, 2022 | Beetham Thomas W. | See Remarks | Grant(A) | 3K | $0.94 | $3K |
| Aug 15, 2022 | Vasconcelles Michael | Director | Grant(A) | 40K | — | $0 |
| Aug 1, 2022 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 75K | — | $0 |
| Aug 1, 2022 | Stants Kristen | Chief People Officer | Grant(A) | 85K | — | $0 |
| Aug 1, 2022 | Mahoney Stephen F. | See Remarks | Grant(A) | 130K | — | $0 |
| Aug 1, 2022 | Nichols David Wayne | Chief Technical Officer | Grant(A) | 75K | — | $0 |
| Aug 1, 2022 | Gardner Jason | See Remarks, Director | Grant(A) | 188K | — | $0 |
| Aug 1, 2022 | Humphrey Jeffrey | Chief Medical Officer | Grant(A) | 75K | — | $0 |
| Aug 1, 2022 | Beetham Thomas W. | See Remarks | Grant(A) | 75K | — | $0 |
| Aug 1, 2022 | Olson Lisa | See Remarks | Grant(A) | 100K | — | $0 |
| Jun 28, 2022 | McGeorge Anne | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Scadden David | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Albers Jeffrey W. | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Ronneberg Amy L | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Lawton Alison Frances | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Daniel Thomas O | Director | Grant(A) | 20K | — | $0 |
| Jun 28, 2022 | Booth Bruce | Director | Grant(A) | 20K | — | $0 |
| May 31, 2022 | Beetham Thomas W. | See Remarks | Grant(A) | 3K | $0.99 | $3K |
| May 31, 2022 | Gardner Jason | See Remarks, Director | Grant(A) | 3K | $0.99 | $3K |
| May 31, 2022 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 3K | $0.99 | $3K |
| May 31, 2022 | Stants Kristen | Chief People Officer | Grant(A) | 3K | $0.99 | $3K |
| May 17, 2022 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 50K | — | $0 |
| May 17, 2022 | Beetham Thomas W. | See Remarks | Grant(A) | 50K | — | $0 |
| May 17, 2022 | Mahoney Stephen F. | See Remarks | Grant(A) | 63K | — | $0 |
| May 17, 2022 | Nichols David Wayne | Chief Technical Officer | Grant(A) | 50K | — | $0 |
| May 17, 2022 | Stants Kristen | Chief People Officer | Grant(A) | 50K | — | $0 |
| May 17, 2022 | Gardner Jason | See Remarks, Director | Grant(A) | 163K | — | $0 |
| May 17, 2022 | Humphrey Jeffrey | Chief Medical Officer | Grant(A) | 50K | — | $0 |
| May 17, 2022 | Olson Lisa | See Remarks | Grant(A) | 50K | — | $0 |
| Feb 15, 2022 | Beetham Thomas W. | See Remarks | Grant(A) | 75K | — | $0 |
| Feb 15, 2022 | Mahoney Stephen F. | See Remarks | Grant(A) | 130K | — | $0 |
| Feb 15, 2022 | Olson Lisa | See Remarks | Grant(A) | 100K | — | $0 |
| Feb 15, 2022 | Nichols David Wayne | Chief Technical Officer | Grant(A) | 75K | — | $0 |
| Feb 15, 2022 | Stants Kristen | Chief People Officer | Grant(A) | 85K | — | $0 |
| Feb 15, 2022 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 75K | — | $0 |
| Feb 15, 2022 | Humphrey Jeffrey | Chief Medical Officer | Grant(A) | 75K | — | $0 |
| Feb 15, 2022 | Gardner Jason | See Remarks, Director | Grant(A) | 188K | — | $0 |
| Oct 1, 2021 | Humphrey Jeffrey | Chief Medical Officer | Grant(A) | 275K | — | $0 |
| Sep 16, 2021 | Nichols David Wayne | Chief Technical Officer | Sell(S) | 6K | $6.73 | $38K |
| Sep 16, 2021 | Olson Lisa | See Remarks | Sell(S) | 6K | $6.73 | $39K |
| Sep 16, 2021 | Beetham Thomas W. | See Remarks | Sell(S) | 6K | $6.73 | $41K |
| Sep 16, 2021 | Gardner Jason | See Remarks | Sell(S) | 14K | $6.73 | $97K |
| Sep 16, 2021 | Deardorf Caren | Chief Commercial Officer | Sell(S) | 6K | $6.73 | $42K |
| Sep 16, 2021 | Mahoney Stephen F. | See Remarks | Sell(S) | 6K | $6.73 | $39K |
| Sep 16, 2021 | Stants Kristen | Chief People Officer | Sell(S) | 6K | $6.73 | $39K |
| Sep 14, 2021 | Beetham Thomas W. | See Remarks | Grant(A) | 20K | — | $0 |
| Sep 14, 2021 | Nichols David Wayne | Chief Technical Officer | Grant(A) | 20K | — | $0 |
| Sep 14, 2021 | Gardner Jason | See Remarks, Director | Grant(A) | 50K | — | $0 |
| Sep 14, 2021 | Mahoney Stephen F. | See Remarks | Grant(A) | 20K | — | $0 |
| Sep 14, 2021 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 20K | — | $0 |
| Sep 14, 2021 | Stants Kristen | Chief People Officer | Grant(A) | 20K | — | $0 |
| Sep 14, 2021 | Olson Lisa | See Remarks | Grant(A) | 20K | — | $0 |
| Aug 26, 2021 | Borisy Alexis | Director | Other(J) | 4K | — | $0 |
| Aug 25, 2021 | Third Rock Ventures GP IV, L.P. | 10% Owner | Other(J) | 1.3M | — | — |
| Aug 2, 2021 | Gardner Jason | See Remarks, Director | Grant(A) | 113K | — | $0 |
| Aug 2, 2021 | Stants Kristen | Chief People Officer | Grant(A) | 68K | — | $0 |
| Aug 2, 2021 | Olson Lisa | See Remarks | Grant(A) | 13K | — | $0 |
| Jul 20, 2021 | Olson Lisa | See Remarks | Grant(A) | 50K | — | $0 |
| Jul 6, 2021 | Deardorf Caren | Chief Commercial Officer | Grant(A) | 200K | — | $0 |
| Jun 14, 2021 | Beetham Thomas W. | See Remarks | Grant(A) | 200K | — | $0 |
| Jun 1, 2021 | Albers Jeffrey W. | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Borisy Alexis | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Daniel Thomas O | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Scadden David | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Bonney Michael W | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Ronneberg Amy L | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Booth Bruce | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | Lawton Alison Frances | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2021 | McGeorge Anne | Director | Grant(A) | 18K | — | $0 |
| Apr 19, 2021 | Nichols David Wayne | Chief Technical Officer | Grant(A) | 175K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).