The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 9, 2026 | Dorton Katina | Director | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Babler Martin | Director | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Sandor Victor | Director | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Bonita David P | Director, 10% Owner | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Friedman Paul A | Director | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Baker Bros. Advisors LP | Director, 10% Owner | Grant(A) | 38K | — | $0 |
| Jun 9, 2026 | Baker Bros. Advisors LP | Director, 10% Owner | Grant(A) | 38K | — | $0 |
| Feb 4, 2026 | Lim Bryant David | CLO, CFO, Corp Sec. | Grant(A) | 275K | — | $0 |
| Feb 4, 2026 | Scherle Peggy | Chief Scientific Officer | Grant(A) | 230K | — | $0 |
| Feb 4, 2026 | Vaddi Krishna | CEO, Director | Grant(A) | 837K | — | $0 |
| Feb 4, 2026 | Combs Andrew | Chief Chemistry Officer | Grant(A) | 230K | — | $0 |
| Nov 5, 2025 | Sandor Victor | Director | Grant(A) | 121K | — | $0 |
| Oct 17, 2025 | Dorton Katina | Director | Grant(A) | 76K | — | $0 |
| Oct 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Oct 4, 2025 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $1.47 | $5K |
| Oct 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jul 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Jul 4, 2025 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $0.79 | $3K |
| Jul 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jun 12, 2025 | Baker Brothers Life Sciences LP | Director, 10% Owner | Grant(A) | 76K | — | $0 |
| Jun 12, 2025 | Baker Brothers Life Sciences LP | Director, 10% Owner | Grant(A) | 76K | — | $0 |
| Jun 12, 2025 | Babler Martin | Director | Grant(A) | 38K | — | $0 |
| Jun 12, 2025 | Bonita David P | Director, 10% Owner | Grant(A) | 38K | — | $0 |
| Jun 12, 2025 | Friedman Paul A | Director | Grant(A) | 38K | — | $0 |
| Jun 12, 2025 | Dier Mardi | Director | Grant(A) | 38K | — | $0 |
| Jun 12, 2025 | Sandor Victor | Director | Grant(A) | 38K | — | $0 |
| Apr 4, 2025 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $0.68 | $2K |
| Apr 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Apr 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Mar 25, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 675K | $0.69 | $466K |
| Mar 25, 2025 | Combs Andrew | Chief Chemistry Officer | Buy(P) | 100K | $0.69 | $69K |
| Mar 21, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 15K | $0.73 | $11K |
| Mar 20, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 5K | $0.73 | $4K |
| Mar 17, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 9K | $0.75 | $7K |
| Mar 14, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 30K | $0.75 | $22K |
| Mar 13, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 50K | $0.72 | $36K |
| Mar 12, 2025 | Vaddi Krishna | CEO, Director | Buy(P) | 48K | $0.71 | $34K |
| Feb 4, 2025 | Vaddi Krishna | CEO, Director | Grant(A) | 496K | — | $0 |
| Feb 4, 2025 | Huang Jane | President, CMO | Grant(A) | 200K | — | $0 |
| Feb 4, 2025 | Combs Andrew | Chief Chemistry Officer | Grant(A) | 175K | — | $0 |
| Feb 4, 2025 | Scherle Peggy | Chief Scientific Officer | Grant(A) | 175K | — | $0 |
| Feb 4, 2025 | Lim Bryant David | CLO, CFO, Corp Sec. | Grant(A) | 200K | — | $0 |
| Jan 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Jan 4, 2025 | Huang Jane | President, CMO | Tax withholding(F) | 4K | $1.39 | $5K |
| Jan 4, 2025 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Dec 31, 2024 | Vaddi Krishna | CEO, Director | Buy(P) | 5K | $1.21 | $6K |
| Dec 30, 2024 | Vaddi Krishna | CEO, Director | Buy(P) | 10K | $1.20 | $12K |
| Dec 23, 2024 | Combs Andrew | Chief Chemistry Officer | Buy(P) | 60K | $1.37 | $82K |
| Dec 20, 2024 | Combs Andrew | Chief Chemistry Officer | Buy(P) | 3K | $1.15 | $4K |
| Dec 19, 2024 | Vaddi Krishna | CEO, Director | Buy(P) | 7K | $0.89 | $6K |
| Dec 19, 2024 | Lim Bryant David | CLO, Interim CFO, Corp Sec. | Buy(P) | 25K | $0.91 | $23K |
| Dec 18, 2024 | Vaddi Krishna | CEO, Director | Buy(P) | 100K | $0.93 | $93K |
| Oct 4, 2024 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $2.00 | $7K |
| Oct 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Oct 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jul 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Jul 4, 2024 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $3.60 | $12K |
| Jul 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jun 14, 2024 | Sandor Victor | Director | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Friedman Paul A | Director | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Dier Mardi | Director | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Bonita David P | Director, 10% Owner | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Babler Martin | Director | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Baker Bros. Advisors (GP) LLC | Director, 10% Owner | Grant(A) | 24K | — | $0 |
| Jun 14, 2024 | Baker Bros. Advisors (GP) LLC | Director, 10% Owner | Grant(A) | 24K | — | $0 |
| May 14, 2024 | Lim Bryant David | CLO, Interim CFO, Corp Sec. | Grant(A) | 25K | — | $0 |
| Apr 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Apr 4, 2024 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $4.74 | $16K |
| Apr 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Mar 1, 2024 | Lim Bryant David | Chief Legal Officer, Corp Sec. | Grant(A) | 150K | — | $0 |
| Mar 1, 2024 | Scherle Peggy | Chief Scientific Officer | Grant(A) | 150K | — | $0 |
| Mar 1, 2024 | Combs Andrew | Chief Chemistry Officer | Grant(A) | 150K | — | $0 |
| Mar 1, 2024 | Chardonnet Laurent | Chief Financial Officer | Grant(A) | 150K | — | $0 |
| Mar 1, 2024 | Huang Jane | President, CMO | Grant(A) | 175K | — | $0 |
| Mar 1, 2024 | Vaddi Krishna | CEO, Director | Grant(A) | 425K | — | $0 |
| Jan 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jan 4, 2024 | Huang Jane | President, CMO | Tax withholding(F) | 4K | $3.77 | $14K |
| Jan 4, 2024 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Dec 13, 2023 | Baker Brothers Life Sciences LP | Director, 10% Owner | Grant(A) | 7.3M | $3.15 | $23.1M |
| Dec 13, 2023 | Baker Brothers Life Sciences LP | Director, 10% Owner | Grant(A) | 593K | $3.15 | $1.9M |
| Oct 4, 2023 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Oct 4, 2023 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| Jul 4, 2023 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | $0 |
| Jul 4, 2023 | Huang Jane | President, CMO | Tax withholding(F) | 3K | $4.65 | $15K |
| Jul 4, 2023 | Huang Jane | President, CMO | Option exercise(M) | 9K | — | — |
| May 22, 2023 | Orbimed Capital LLC | Director, 10% Owner | Buy(P) | 870K | $5.75 | $5.0M |
| May 22, 2023 | Bonita David P | Director, 10% Owner | Buy(P) | 870K | $5.75 | $5.0M |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).