The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Apr 20, 2026 | Kenney Stephanie | See Remarks | Grant(A) | 60K | — | $0 |
| Apr 20, 2026 | Kenney Stephanie | See Remarks | Grant(A) | 30K | — | $0 |
| Apr 20, 2026 | Hughes Steven George | Chief Medical Officer | Grant(A) | 60K | — | $0 |
| Apr 20, 2026 | Hughes Steven George | Chief Medical Officer | Grant(A) | 30K | — | $0 |
| Apr 20, 2026 | Winslow Brendan R. | Chief Financial Officer | Grant(A) | 60K | — | $0 |
| Apr 20, 2026 | Winslow Brendan R. | Chief Financial Officer | Grant(A) | 30K | — | $0 |
| Apr 20, 2026 | Gallagher Kathleen P. | See Remarks, Director | Grant(A) | 205K | — | $0 |
| Apr 20, 2026 | Gallagher Kathleen P. | See Remarks, Director | Grant(A) | 103K | — | $0 |
| Apr 20, 2026 | Hoyos Rocio Martin | Chief Strategy Officer | Grant(A) | 60K | — | $0 |
| Apr 20, 2026 | Hoyos Rocio Martin | Chief Strategy Officer | Grant(A) | 30K | — | $0 |
| Apr 20, 2026 | Younis Husam | Chief Scientific Officer | Grant(A) | 60K | — | $0 |
| Apr 20, 2026 | Younis Husam | Chief Scientific Officer | Grant(A) | 30K | — | $0 |
| Feb 27, 2026 | Skerjanec Simona | Director | Grant(A) | 20K | — | $0 |
| Feb 27, 2026 | Flanagan W. Michael | Director | Grant(A) | 20K | — | $0 |
| Feb 27, 2026 | Wilson Troy Edward | Director | Grant(A) | 20K | — | $0 |
| Feb 27, 2026 | Boess Carsten | Director | Grant(A) | 20K | — | $0 |
| Feb 27, 2026 | Boyce Sarah | Director | Grant(A) | 20K | — | $0 |
| Jan 21, 2026 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 1K | $72.45 | $107K |
| Jan 21, 2026 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 1K | $72.45 | $105K |
| Jan 21, 2026 | Levin Arthur A | Director | Sell(S) | 2K | $72.45 | $127K |
| Jan 21, 2026 | MacLean Michael F | Chief Financial Officer | Sell(S) | 3K | $72.45 | $198K |
| Jan 21, 2026 | MacLean Michael F | Chief Financial Officer | Sell(S) | 2K | $72.45 | $131K |
| Jan 21, 2026 | Flanagan W. Michael | Chief Scientific Officer | Sell(S) | 3K | $72.45 | $185K |
| Jan 21, 2026 | Flanagan W. Michael | Chief Scientific Officer | Sell(S) | 4K | $72.45 | $288K |
| Jan 21, 2026 | Boyce Sarah | President and CEO, Director | Sell(S) | 6K | $72.45 | $463K |
| Jan 21, 2026 | Boyce Sarah | President and CEO, Director | Sell(S) | 8K | $72.45 | $579K |
| Jan 21, 2026 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $72.45 | $146K |
| Jan 21, 2026 | Hughes Steven George | Chief Medical Officer | Sell(S) | 3K | $72.45 | $209K |
| Jan 7, 2026 | Flanagan W. Michael | Chief Scientific Officer | Sell(S) | 2K | $72.23 | $171K |
| Jan 7, 2026 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $72.23 | $171K |
| Jan 7, 2026 | MacLean Michael F | Chief Financial Officer | Sell(S) | 2K | $72.23 | $143K |
| Jan 7, 2026 | Moriarty John B | Chief Legal Officer | Sell(S) | 2K | $72.23 | $171K |
| Jan 7, 2026 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 2K | $72.23 | $142K |
| Jan 7, 2026 | Calderaro Charles III | Chief Technical Officer | Sell(S) | 4K | $72.23 | $269K |
| Jan 7, 2026 | Boyce Sarah | President and CEO, Director | Sell(S) | 9K | $72.23 | $619K |
| Dec 19, 2025 | Levin Arthur A | Director | Gift(G) | 1K | — | $0 |
| Dec 18, 2025 | Boyce Sarah | President and CEO, Director | Gift(G) | 29K | — | $0 |
| Dec 17, 2025 | McCarthy Teresa | Chief Human Resources Officer | Grant(A) | 39K | — | $0 |
| Dec 17, 2025 | McCarthy Teresa | Chief Human Resources Officer | Tax withholding(F) | 17K | $71.87 | $1.2M |
| Dec 17, 2025 | Gallagher Kathleen P. | Chief Program Officer | Grant(A) | 72K | — | $0 |
| Dec 17, 2025 | Gallagher Kathleen P. | Chief Program Officer | Tax withholding(F) | 8K | $71.87 | $577K |
| Dec 17, 2025 | Gallagher Kathleen P. | Chief Program Officer | Tax withholding(F) | 33K | $71.87 | $2.4M |
| Dec 17, 2025 | Moriarty John B | Chief Legal Officer | Tax withholding(F) | 27K | $71.87 | $1.9M |
| Dec 17, 2025 | Moriarty John B | Chief Legal Officer | Grant(A) | 56K | — | $0 |
| Dec 17, 2025 | Boyce Sarah | President and CEO, Director | Grant(A) | 31K | — | $0 |
| Dec 17, 2025 | Boyce Sarah | President and CEO, Director | Tax withholding(F) | 16K | $71.87 | $1.1M |
| Dec 17, 2025 | Mosbrooker Eric | Chief Commercial Officer | Grant(A) | 72K | — | $0 |
| Dec 17, 2025 | Mosbrooker Eric | Chief Commercial Officer | Tax withholding(F) | 37K | $71.87 | $2.6M |
| Dec 17, 2025 | Mosbrooker Eric | Chief Commercial Officer | Tax withholding(F) | 11K | $71.87 | $821K |
| Dec 17, 2025 | Flanagan W. Michael | Chief Scientific Officer | Tax withholding(F) | 14K | $71.87 | $984K |
| Dec 17, 2025 | Flanagan W. Michael | Chief Scientific Officer | Grant(A) | 28K | — | $0 |
| Dec 17, 2025 | Calderaro Charles III | Chief Technical Officer | Grant(A) | 23K | — | $0 |
| Dec 17, 2025 | Calderaro Charles III | Chief Technical Officer | Tax withholding(F) | 10K | $71.87 | $699K |
| Oct 22, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $47.54 | $105K |
| Oct 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | $10.16 | $22K |
| Oct 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | — | $0 |
| Oct 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 20K | $50.15 | $1.0M |
| Oct 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 20K | $22.34 | $447K |
| Oct 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 20K | — | $0 |
| Oct 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Sell(S) | 7K | $45.38 | $298K |
| Oct 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Option exercise(M) | 7K | $9.05 | $59K |
| Oct 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Option exercise(M) | 7K | — | $0 |
| Sep 22, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $40.58 | $90K |
| Sep 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | $10.16 | $22K |
| Sep 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | — | $0 |
| Sep 15, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $45.41 | $70K |
| Sep 15, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | $6.57 | $10K |
| Sep 15, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | — | $0 |
| Sep 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 15K | $22.34 | $335K |
| Sep 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 15K | $41.41 | $621K |
| Sep 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 15K | — | $0 |
| Sep 11, 2025 | Flanagan W. Michael | Chief Scientific Officer | Sell(S) | 20K | $38.94 | $779K |
| Sep 11, 2025 | Flanagan W. Michael | Chief Scientific Officer | Option exercise(M) | 20K | $14.22 | $284K |
| Sep 11, 2025 | Flanagan W. Michael | Chief Scientific Officer | Option exercise(M) | 20K | — | $0 |
| Sep 5, 2025 | Boyce Sarah | President and CEO, Director | Sell(S) | 50K | $49.95 | $2.5M |
| Sep 5, 2025 | Boyce Sarah | President and CEO, Director | Option exercise(M) | 50K | $1.24 | $62K |
| Sep 5, 2025 | Boyce Sarah | President and CEO, Director | Option exercise(M) | 50K | — | $0 |
| Sep 5, 2025 | Wilson Troy Edward | Director | Option exercise(M) | 15K | $12.48 | $181K |
| Sep 5, 2025 | Wilson Troy Edward | Director | Sell(S) | 15K | $50.00 | $750K |
| Sep 5, 2025 | Wilson Troy Edward | Director | Sell(S) | 15K | $50.00 | $725K |
| Sep 5, 2025 | Wilson Troy Edward | Director | Option exercise(M) | 15K | — | $0 |
| Sep 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Option exercise(M) | 7K | $9.05 | $59K |
| Sep 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Sell(S) | 7K | $47.07 | $309K |
| Sep 3, 2025 | Mosbrooker Eric | Chief Commercial Officer | Option exercise(M) | 7K | — | $0 |
| Sep 2, 2025 | Gallagher Kathleen P. | Chief Program Officer | Sell(S) | 188 | $47.42 | $9K |
| Aug 28, 2025 | Boyce Sarah | President and CEO, Director | Option exercise(M) | 25K | $1.24 | $31K |
| Aug 28, 2025 | Boyce Sarah | President and CEO, Director | Sell(S) | 25K | $49.39 | $1.2M |
| Aug 28, 2025 | Boyce Sarah | President and CEO, Director | Option exercise(M) | 25K | — | $0 |
| Aug 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | $10.16 | $22K |
| Aug 22, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $46.40 | $102K |
| Aug 22, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | — | $0 |
| Aug 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 10K | $22.34 | $223K |
| Aug 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Sell(S) | 10K | $46.56 | $466K |
| Aug 15, 2025 | McCarthy Teresa | Chief Human Resources Officer | Option exercise(M) | 10K | — | $0 |
| Aug 13, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | $6.57 | $10K |
| Aug 13, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 2K | $46.66 | $72K |
| Aug 13, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 2K | — | $0 |
| Aug 6, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 18K | $42.74 | $755K |
| Aug 6, 2025 | Hughes Steven George | Chief Medical Officer | Sell(S) | 34K | $42.74 | $1.5M |
| Aug 6, 2025 | Hughes Steven George | Chief Medical Officer | Option exercise(M) | 11K | $15.96 | $180K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).