The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 29, 2026 | Patel Sushil | Director | Option exercise(M) | 3K | $37.54 | $111K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 300 | $183.17 | $55K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 900 | $184.59 | $166K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 1K | $185.90 | $204K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 858 | $186.92 | $160K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 300 | $187.83 | $56K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 100 | $188.57 | $19K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 600 | $190.55 | $114K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 541 | $191.87 | $104K |
| Jun 29, 2026 | Patel Sushil | Director | Sell(S) | 881 | $192.61 | $170K |
| Jun 29, 2026 | Patel Sushil | Director | Option exercise(M) | 3K | — | $0 |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Option exercise(M) | 20K | $18.56 | $371K |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 5K | $167.35 | $762K |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 9K | $168.20 | $1.6M |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 6K | $169.24 | $956K |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 300 | $170.32 | $51K |
| Jun 24, 2026 | Anders Jack | Chief Financial Officer | Option exercise(M) | 20K | — | $0 |
| Jun 18, 2026 | Anderson Elizabeth M | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Anderson Elizabeth M | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Horning Sandra | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Horning Sandra | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Clyburn Frank | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Clyburn Frank | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Patel Sushil | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Patel Sushil | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Borellini Flavia | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Borellini Flavia | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Kim Lorence H. | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Kim Lorence H. | Director | Grant(A) | 3K | — | $0 |
| Jun 18, 2026 | Borisy Alexis | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2026 | Borisy Alexis | Director | Grant(A) | 3K | — | $0 |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 573 | $40.74 | $23K |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 3K | $29.80 | $98K |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 26K | $26.50 | $682K |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 30K | $160.12 | $4.7M |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 573 | — | $0 |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 3K | — | $0 |
| Jun 17, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 26K | — | $0 |
| Jun 16, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 3K | $156.12 | $425K |
| Jun 16, 2026 | Cislini Jeff | General Counsel | Sell(S) | 2K | $156.12 | $337K |
| Jun 16, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 10K | $156.12 | $1.6M |
| Jun 16, 2026 | Kelsey Stephen Michael | See Remarks | Sell(S) | 4K | $156.12 | $652K |
| Jun 16, 2026 | Mancini Anthony | See Remarks | Sell(S) | 5K | $156.12 | $720K |
| Jun 15, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 16K | $40.74 | $633K |
| Jun 15, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 45K | $29.80 | $1.3M |
| Jun 15, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 60K | $160.17 | $9.7M |
| Jun 15, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 16K | — | $0 |
| Jun 15, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 45K | — | $0 |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 1K | $42.45 | $46K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 9K | $40.74 | $363K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 1K | $144.28 | $190K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 885 | $145.15 | $128K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 700 | $146.04 | $102K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 500 | $147.27 | $74K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 2K | $148.72 | $268K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 5K | $149.64 | $688K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 200 | $150.17 | $30K |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 1K | — | $0 |
| Jun 11, 2026 | Horn Margaret A | Chief Operating Officer | Option exercise(M) | 9K | — | $0 |
| May 26, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 3K | — | $0 |
| May 26, 2026 | Mancini Anthony | See Remarks | Sell(S) | 421 | $154.82 | $65K |
| May 26, 2026 | Mancini Anthony | See Remarks | Sell(S) | 2K | $154.06 | $308K |
| May 26, 2026 | Mancini Anthony | See Remarks | Sell(S) | 700 | $153.30 | $107K |
| May 26, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 3K | $33.62 | $105K |
| Apr 27, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 3K | — | $0 |
| Apr 27, 2026 | Mancini Anthony | See Remarks | Sell(S) | 400 | $134.34 | $54K |
| Apr 27, 2026 | Mancini Anthony | See Remarks | Sell(S) | 1K | $132.88 | $139K |
| Apr 27, 2026 | Mancini Anthony | See Remarks | Sell(S) | 2K | $131.66 | $220K |
| Apr 27, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 3K | $33.62 | $105K |
| Apr 15, 2026 | Goldsmith Mark A | See Remarks, Director | Option exercise(M) | 97K | — | $0 |
| Apr 15, 2026 | Goldsmith Mark A | See Remarks, Director | Option exercise(M) | 23K | — | $0 |
| Apr 15, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 120K | $150.09 | $18.0M |
| Apr 15, 2026 | Goldsmith Mark A | See Remarks, Director | Option exercise(M) | 97K | $4.73 | $458K |
| Apr 15, 2026 | Goldsmith Mark A | See Remarks, Director | Option exercise(M) | 23K | $4.09 | $95K |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Sell(S) | 400 | $97.21 | $39K |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Sell(S) | 11K | $96.43 | $1.1M |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Sell(S) | 21K | $95.49 | $2.0M |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Sell(S) | 3K | $94.16 | $295K |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Sell(S) | 2K | $93.22 | $168K |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 37K | $33.62 | $1.3M |
| Mar 25, 2026 | Mancini Anthony | See Remarks | Option exercise(M) | 37K | — | $0 |
| Mar 19, 2026 | Cislini Jeff | General Counsel | Sell(S) | 1K | $97.44 | $113K |
| Mar 17, 2026 | Wang Xiaolin | See Remarks | Sell(S) | 2K | $99.48 | $200K |
| Mar 17, 2026 | Cislini Jeff | General Counsel | Sell(S) | 2K | $99.48 | $179K |
| Mar 17, 2026 | Anders Jack | Chief Financial Officer | Sell(S) | 3K | $99.48 | $274K |
| Mar 17, 2026 | Horn Margaret A | Chief Operating Officer | Sell(S) | 5K | $99.48 | $456K |
| Mar 17, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 13K | $99.48 | $1.3M |
| Mar 17, 2026 | Kelsey Stephen Michael | See Remarks | Sell(S) | 4K | $99.48 | $428K |
| Mar 17, 2026 | Wei Lin | Chief Medical Officer | Sell(S) | 2K | $99.48 | $206K |
| Mar 4, 2026 | Anderson Elizabeth M | Director | Gift(G) | 15K | — | $0 |
| Mar 4, 2026 | Anderson Elizabeth M | Director | Gift(G) | 15K | — | $0 |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 4K | $100.73 | $365K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 21K | $101.60 | $2.2M |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 100 | $98.31 | $10K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 400 | $100.12 | $40K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 2K | $101.47 | $172K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 800 | $102.00 | $82K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 100 | $98.29 | $10K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 600 | $100.19 | $60K |
| Mar 2, 2026 | Goldsmith Mark A | See Remarks, Director | Sell(S) | 2K | $101.63 | $213K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-11. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).