The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 18K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 18K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 30K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 30K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 8K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 8K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 19K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 19K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 21K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 21K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 12K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 12K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 15K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 15K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 30K | — | $0 |
| Jul 16, 2026 | Harrison Seth Loring | Director | Gift(G) | 30K | — | $0 |
| Jul 15, 2026 | McCauley Thomas | Chief Scientific Officer | Grant(A) | 225K | — | $0 |
| Jul 1, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 7K | $32.62 | $219K |
| Jul 1, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 500 | $33.27 | $17K |
| Jun 16, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 1K | $29.95 | $44K |
| Jun 3, 2026 | Krainer Adrian R. | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Kaye Edward M. MD | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Harrison Seth Loring | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Tzianabos Arthur | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Smith Julie | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Burstein Jennifer | Director | Grant(A) | 18K | — | $0 |
| Jun 3, 2026 | Levin Arthur A | Director | Grant(A) | 18K | — | $0 |
| Jun 1, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 2K | $30.58 | $55K |
| May 1, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 2K | $32.79 | $74K |
| Apr 3, 2026 | Kahn Clare | Director | Grant(A) | 31K | — | $0 |
| Apr 1, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 2K | $32.66 | $60K |
| Mar 20, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 9K | $33.64 | $292K |
| Mar 20, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 601 | $34.41 | $21K |
| Mar 19, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 1K | $29.99 | $44K |
| Mar 19, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 1K | $2.19 | $3K |
| Mar 19, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 1K | — | $0 |
| Mar 18, 2026 | Hoitt Jason | Chief Patient Officer | Sell(S) | 139 | $31.79 | $4K |
| Mar 18, 2026 | Hoitt Jason | Chief Patient Officer | Sell(S) | 2K | $31.28 | $55K |
| Mar 18, 2026 | Hoitt Jason | Chief Patient Officer | Sell(S) | 30 | $32.85 | $986 |
| Mar 18, 2026 | Leggett Thomas | Chief Financial Officer | Sell(S) | 37 | $32.85 | $1K |
| Mar 18, 2026 | Leggett Thomas | Chief Financial Officer | Sell(S) | 172 | $31.79 | $5K |
| Mar 18, 2026 | Leggett Thomas | Chief Financial Officer | Sell(S) | 2K | $31.28 | $68K |
| Mar 18, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 6K | $31.28 | $191K |
| Mar 18, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 103 | $32.85 | $3K |
| Mar 18, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 483 | $31.79 | $15K |
| Mar 18, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 4K | $31.28 | $132K |
| Mar 18, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 72 | $32.85 | $2K |
| Mar 18, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 334 | $31.79 | $11K |
| Mar 17, 2026 | Hoitt Jason | Chief Patient Officer | Sell(S) | 748 | $33.38 | $25K |
| Mar 17, 2026 | Hoitt Jason | Chief Patient Officer | Sell(S) | 1K | $32.74 | $34K |
| Mar 17, 2026 | Leggett Thomas | Chief Financial Officer | Sell(S) | 922 | $33.38 | $31K |
| Mar 17, 2026 | Leggett Thomas | Chief Financial Officer | Sell(S) | 1K | $32.74 | $42K |
| Mar 17, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 4K | $32.74 | $117K |
| Mar 17, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Sell(S) | 3K | $33.38 | $86K |
| Mar 17, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 2K | $32.74 | $81K |
| Mar 17, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 2K | $33.38 | $60K |
| Mar 15, 2026 | Kaye Edward M. MD | Director | Option exercise(M) | 36K | — | $0 |
| Mar 15, 2026 | Kaye Edward M. MD | Director | Option exercise(M) | 26K | — | $0 |
| Mar 15, 2026 | Kaye Edward M. MD | Director | Option exercise(M) | 36K | — | $0 |
| Mar 15, 2026 | Kaye Edward M. MD | Director | Option exercise(M) | 26K | — | $0 |
| Mar 15, 2026 | Hoitt Jason | Chief Patient Officer | Option exercise(M) | 10K | — | $0 |
| Mar 15, 2026 | Hoitt Jason | Chief Patient Officer | Option exercise(M) | 10K | — | $0 |
| Mar 15, 2026 | Leggett Thomas | Chief Financial Officer | Option exercise(M) | 15K | — | $0 |
| Mar 15, 2026 | Leggett Thomas | Chief Financial Officer | Option exercise(M) | 15K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 11K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 13K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 10K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 13K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 10K | — | $0 |
| Mar 15, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Option exercise(M) | 11K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 6K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 12K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 7K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 7K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 6K | — | $0 |
| Mar 15, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Option exercise(M) | 12K | — | $0 |
| Mar 13, 2026 | Levin Arthur A | Director | Sell(S) | 605 | $36.80 | $22K |
| Mar 10, 2026 | Tzianabos Arthur | Interim Executive Chair, Director | Sell(S) | 4K | $40.00 | $174K |
| Mar 10, 2026 | Tzianabos Arthur | Interim Executive Chair, Director | Option exercise(M) | 4K | $8.33 | $33K |
| Mar 10, 2026 | Tzianabos Arthur | Interim Executive Chair, Director | Option exercise(M) | 4K | — | $0 |
| Mar 10, 2026 | Krainer Adrian R. | Director | Sell(S) | 33K | $39.74 | $1.3M |
| Mar 2, 2026 | Krainer Adrian R. | Director | Sell(S) | 7K | $39.66 | $287K |
| Feb 17, 2026 | Smith Ian F | Chief Executive Officer, Director | Grant(A) | 193K | — | $0 |
| Feb 17, 2026 | Smith Ian F | Chief Executive Officer, Director | Grant(A) | 129K | — | $0 |
| Feb 17, 2026 | Hoitt Jason | Chief Patient Officer | Grant(A) | 72K | — | $0 |
| Feb 17, 2026 | Hoitt Jason | Chief Patient Officer | Grant(A) | 48K | — | $0 |
| Feb 17, 2026 | Leggett Thomas | Chief Financial Officer | Grant(A) | 60K | — | $0 |
| Feb 17, 2026 | Leggett Thomas | Chief Financial Officer | Grant(A) | 40K | — | $0 |
| Feb 17, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Grant(A) | 40K | — | $0 |
| Feb 17, 2026 | Ticho Barry | CHIEF MEDICAL OFFICER | Grant(A) | 60K | — | $0 |
| Feb 17, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Grant(A) | 35K | — | $0 |
| Feb 17, 2026 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Grant(A) | 53K | — | $0 |
| Dec 31, 2025 | Levin Arthur A | Director | Option exercise(M) | 1K | — | $0 |
| Dec 31, 2025 | Levin Arthur A | Director | Option exercise(M) | 1K | — | $0 |
| Dec 8, 2025 | Kaye Edward M. MD | Director | Sell(S) | 8K | $32.52 | $269K |
| Dec 8, 2025 | Kaye Edward M. MD | Director | Sell(S) | 4K | $31.44 | $120K |
| Dec 8, 2025 | Kaye Edward M. MD | Director | Sell(S) | 1K | $33.10 | $44K |
| Dec 8, 2025 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 3K | $32.61 | $87K |
| Dec 8, 2025 | Allan Jonathan | GENERAL COUNSEL & CORP SEC | Sell(S) | 1K | $31.60 | $41K |
| Dec 5, 2025 | Kaye Edward M. MD | Director | Sell(S) | 500 | $31.85 | $16K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-18. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).