The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | — | $0 |
| Jul 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 7K | $30.25 | $223K |
| Jul 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 20K | $29.34 | $576K |
| Jul 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | $5.20 | $140K |
| Jun 19, 2026 | Azelby Robert | Director | Grant(A) | 36K | — | $0 |
| Jun 19, 2026 | Azelby Robert | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2026 | Lee Sung | Director | Grant(A) | 570 | — | $0 |
| Jun 5, 2026 | Lee Sung | Director | Grant(A) | 4K | — | $0 |
| Jun 5, 2026 | Rothenberg Mace | Director | Grant(A) | 4K | — | $0 |
| Jun 5, 2026 | Rothenberg Mace | Director | Grant(A) | 25K | — | $0 |
| Jun 5, 2026 | Ketchum John B | Director | Grant(A) | 4K | — | $0 |
| Jun 5, 2026 | Ketchum John B | Director | Grant(A) | 25K | — | $0 |
| Jun 5, 2026 | Calhoun Lesley Ann | Director | Grant(A) | 4K | — | $0 |
| Jun 5, 2026 | Calhoun Lesley Ann | Director | Grant(A) | 25K | — | $0 |
| Jun 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | $5.20 | $140K |
| Jun 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 6K | $22.25 | $137K |
| Jun 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 21K | $23.06 | $481K |
| Jun 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | — | $0 |
| May 1, 2026 | Gall Matthew | Chief Financial Officer | Grant(A) | 240K | — | $0 |
| May 1, 2026 | Gall Matthew | Chief Financial Officer | Grant(A) | 40K | — | $0 |
| May 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | — | $0 |
| May 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 1K | $22.00 | $24K |
| May 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 26K | $21.19 | $549K |
| May 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | $5.20 | $140K |
| Apr 29, 2026 | Lee Sung | Director | Grant(A) | 5K | — | $0 |
| Apr 29, 2026 | Lee Sung | Director | Grant(A) | 12K | — | $0 |
| Apr 15, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 38K | — | $0 |
| Apr 15, 2026 | Crystal Adam | President, R&D | Sell(S) | 38K | $25.00 | $962K |
| Apr 15, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 38K | $5.20 | $200K |
| Apr 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | — | $0 |
| Apr 1, 2026 | Crystal Adam | President, R&D | Sell(S) | 27K | $21.20 | $572K |
| Apr 1, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 27K | $5.20 | $140K |
| Mar 25, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 12K | $5.20 | $62K |
| Mar 25, 2026 | Crystal Adam | President, R&D | Sell(S) | 12K | $20.11 | $241K |
| Mar 25, 2026 | Crystal Adam | President, R&D | Option exercise(M) | 12K | — | $0 |
| Mar 5, 2026 | Crystal Adam | President, R&D | Sell(S) | 20K | $15.00 | $304K |
| Feb 25, 2026 | Crystal Adam | President, R&D | Sell(S) | 54K | $12.77 | $694K |
| Feb 3, 2026 | Crystal Adam | President, R&D | Sell(S) | 201 | $12.90 | $3K |
| Feb 3, 2026 | Crystal Adam | President, R&D | Sell(S) | 18K | $12.26 | $224K |
| Feb 3, 2026 | Weber Barbara | Director, Executive Chair, Director | Sell(S) | 333 | $12.90 | $4K |
| Feb 3, 2026 | Weber Barbara | Director, Executive Chair, Director | Sell(S) | 30K | $12.26 | $370K |
| Feb 3, 2026 | Beckman Daniella | Chief Financial Officer | Sell(S) | 10K | $12.26 | $125K |
| Feb 3, 2026 | Beckman Daniella | Chief Financial Officer | Sell(S) | 113 | $12.90 | $1K |
| Feb 2, 2026 | Crystal Adam | President, R&D | Grant(A) | 47K | — | $0 |
| Feb 2, 2026 | Crystal Adam | President, R&D | Grant(A) | 285K | — | $0 |
| Feb 2, 2026 | Weber Barbara | Director, Executive Chair, Director | Grant(A) | 38K | — | $0 |
| Feb 2, 2026 | Weber Barbara | Director, Executive Chair, Director | Grant(A) | 222K | — | $0 |
| Feb 2, 2026 | Beckman Daniella | Chief Financial Officer | Grant(A) | 44K | — | $0 |
| Feb 2, 2026 | Beckman Daniella | Chief Financial Officer | Grant(A) | 266K | — | $0 |
| Jan 8, 2026 | Peters Malte | President & CEO, Director | Grant(A) | 350K | — | $0 |
| Jan 8, 2026 | Peters Malte | President & CEO, Director | Grant(A) | 1.6M | — | $0 |
| Jan 2, 2026 | Lee Sung | Director | Grant(A) | 10K | — | $0 |
| Jan 2, 2026 | Lee Sung | Director | Grant(A) | 60K | — | $0 |
| Nov 3, 2025 | Peters Malte | Director | Grant(A) | 150K | — | $0 |
| Oct 23, 2025 | TRV GP IV, LLC | 10% Owner | Sell(S) | 477K | $10.15 | $4.8M |
| Sep 25, 2025 | TRV GP IV, LLC | 10% Owner | Sell(S) | 500K | $8.02 | $4.0M |
| Sep 16, 2025 | TRV GP IV, LLC | 10% Owner | Sell(S) | 364K | $7.04 | $2.6M |
| Sep 8, 2025 | TRV GP IV, LLC | 10% Owner | Sell(S) | 86K | $7.04 | $609K |
| Sep 5, 2025 | TRV GP IV, LLC | 10% Owner | Sell(S) | 643K | $7.00 | $4.5M |
| Aug 22, 2025 | Third Rock Ventures GP IV, L.P. | 10% Owner | Sell(S) | 302K | $7.00 | $2.1M |
| Aug 19, 2025 | Third Rock Ventures GP IV, L.P. | 10% Owner | Sell(S) | 1.1M | $7.01 | $7.7M |
| Jun 5, 2025 | Borisy Alexis | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2025 | Borisy Alexis | Director | Grant(A) | 38K | — | $0 |
| Jun 5, 2025 | Ketchum John B | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2025 | Ketchum John B | Director | Grant(A) | 38K | — | $0 |
| Jun 5, 2025 | Rothenberg Mace | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2025 | Rothenberg Mace | Director | Grant(A) | 38K | — | $0 |
| Jun 5, 2025 | Calhoun Lesley Ann | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2025 | Calhoun Lesley Ann | Director | Grant(A) | 38K | — | $0 |
| Jun 5, 2025 | Peters Malte | Director | Grant(A) | 6K | — | $0 |
| Jun 5, 2025 | Peters Malte | Director | Grant(A) | 38K | — | $0 |
| Feb 5, 2025 | Weber Barbara | Chief Executive Officer, Director | Sell(S) | 9K | $3.16 | $28K |
| Feb 5, 2025 | Crystal Adam | See Remarks | Sell(S) | 7K | $3.16 | $22K |
| Feb 5, 2025 | Beckman Daniella | Chief Financial Officer | Sell(S) | 4K | $3.16 | $12K |
| Feb 5, 2025 | Barry Douglas | General Counsel | Sell(S) | 3K | $3.16 | $8K |
| Feb 4, 2025 | Weber Barbara | Chief Executive Officer, Director | Sell(S) | 10K | $2.99 | $29K |
| Feb 4, 2025 | Crystal Adam | See Remarks | Sell(S) | 7K | $2.99 | $22K |
| Feb 4, 2025 | Beckman Daniella | Chief Financial Officer | Sell(S) | 4K | $2.99 | $13K |
| Feb 4, 2025 | Barry Douglas | General Counsel | Sell(S) | 3K | $2.99 | $8K |
| Feb 3, 2025 | Barry Douglas | General Counsel | Grant(A) | 27K | — | $0 |
| Feb 3, 2025 | Barry Douglas | General Counsel | Grant(A) | 164K | — | $0 |
| Feb 3, 2025 | Weber Barbara | Chief Executive Officer, Director | Grant(A) | 106K | — | $0 |
| Feb 3, 2025 | Weber Barbara | Chief Executive Officer, Director | Grant(A) | 635K | — | $0 |
| Feb 3, 2025 | Crystal Adam | See Remarks | Grant(A) | 53K | — | $0 |
| Feb 3, 2025 | Crystal Adam | See Remarks | Grant(A) | 318K | — | $0 |
| Feb 3, 2025 | Beckman Daniella | Chief Financial Officer | Grant(A) | 26K | — | $0 |
| Feb 3, 2025 | Beckman Daniella | Chief Financial Officer | Grant(A) | 157K | — | $0 |
| Nov 18, 2024 | Rothenberg Mace | Director | Buy(P) | 10K | $3.78 | $38K |
| Nov 14, 2024 | Rothenberg Mace | Director | Buy(P) | 10K | $3.62 | $36K |
| Nov 7, 2024 | EcoR1 Capital, LLC | 10% Owner | Sell(S) | 62K | $3.29 | $205K |
| Nov 7, 2024 | EcoR1 Capital, LLC | 10% Owner | Sell(S) | 1.1M | $2.92 | $3.3M |
| Nov 6, 2024 | Boxer Capital Management, LLC | Insider | Sell(S) | 3.1M | $3.14 | $9.7M |
| Nov 6, 2024 | EcoR1 Capital, LLC | 10% Owner | Sell(S) | 1.5M | $3.28 | $4.9M |
| Oct 25, 2024 | Boxer Capital Management, LLC | Insider | Sell(S) | 633K | $6.87 | $4.3M |
| Oct 22, 2024 | Boxer Capital Management, LLC | Insider | Sell(S) | 250K | $6.78 | $1.7M |
| Oct 21, 2024 | Boxer Capital Management, LLC | Insider | Sell(S) | 625K | $7.05 | $4.4M |
| Sep 13, 2024 | TRV GP IV, LLC | 10% Owner | Sell(S) | 67K | $10.53 | $710K |
| Sep 5, 2024 | TRV GP IV, LLC | 10% Owner | Sell(S) | 75K | $11.56 | $867K |
| Sep 3, 2024 | Davis Aaron I. | Insider | Other(J) | 65K | — | $0 |
| Aug 30, 2024 | Third Rock Ventures IV, L.P. | 10% Owner | Sell(S) | 175K | $11.60 | $2.0M |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-21. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).