The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Feb 15, 2026 | Schallenberger Mark A. | Chief Operating Officer | Tax withholding(F) | 8K | $0.58 | $4K |
| Jan 15, 2026 | Neils Scott C | CFO and Assistant Secretary | Tax withholding(F) | 8K | $0.65 | $5K |
| Nov 15, 2025 | Bakewell John K | Director | Grant(A) | 158K | — | $0 |
| Nov 15, 2025 | Bakewell John K | Director | Grant(A) | 158K | — | $0 |
| Nov 15, 2025 | Lipschultz Tyler | Director | Grant(A) | 158K | — | $0 |
| Nov 15, 2025 | Vizirgianakis Stavros G. | Director | Grant(A) | 554K | — | $0 |
| Nov 15, 2025 | Browne Sean E | President and CEO, Director | Grant(A) | 395K | — | $0 |
| Nov 15, 2025 | Browne Sean E | President and CEO, Director | Grant(A) | 790K | — | $0 |
| Nov 15, 2025 | Neils Scott C | CFO and Assistant Secretary | Grant(A) | 263K | — | $0 |
| Nov 15, 2025 | Neils Scott C | CFO and Assistant Secretary | Grant(A) | 527K | — | $0 |
| Nov 15, 2025 | Schallenberger Mark A. | Chief Operating Officer | Grant(A) | 292K | — | $0 |
| Nov 15, 2025 | Schallenberger Mark A. | Chief Operating Officer | Grant(A) | 585K | — | $0 |
| Nov 15, 2025 | Beeson Jonn R. | Director | Grant(A) | 158K | — | $0 |
| Nov 15, 2025 | Jain Abhinav | Director | Grant(A) | 158K | — | $0 |
| Aug 15, 2025 | Neils Scott C | CFO | Tax withholding(F) | 34K | $0.63 | $22K |
| Aug 15, 2025 | Browne Sean E | President and CEO, Director | Tax withholding(F) | 11K | $0.63 | $7K |
| Apr 10, 2025 | Orbimed ROF II LLC | 10% Owner | Sell(S) | 17.1M | $0.42 | $7.2M |
| Apr 10, 2025 | Orbimed ROF II LLC | 10% Owner | Sell(S) | 56.0M | $0.42 | $23.5M |
| Jan 15, 2025 | Neils Scott C | Chief Financial Officer | Tax withholding(F) | 8K | $0.53 | $4K |
| Oct 15, 2024 | Browne Sean E | President and CEO, Director | Tax withholding(F) | 105K | $0.59 | $62K |
| Aug 15, 2024 | Browne Sean E | President and CEO, Director | Tax withholding(F) | 11K | $0.60 | $6K |
| Aug 15, 2024 | Neils Scott C | Chief Financial Officer | Tax withholding(F) | 34K | $0.60 | $20K |
| Aug 15, 2024 | Brandt Kevin D | Chief Commercial Officer | Tax withholding(F) | 56K | $0.60 | $34K |
| Aug 15, 2024 | Bakewell John K | Director | Grant(A) | 162K | — | $0 |
| Aug 15, 2024 | Beeson Jonn R. | Director | Grant(A) | 162K | — | $0 |
| Aug 15, 2024 | McNamara Robert | Director | Grant(A) | 162K | — | $0 |
| Aug 15, 2024 | Mitchell-Keller Lori D | Director | Grant(A) | 162K | — | $0 |
| Aug 15, 2024 | Vizirgianakis Stavros G. | Director | Grant(A) | 505K | — | $0 |
| Aug 15, 2024 | Vizirgianakis Stavros G. | Director | Grant(A) | 243K | — | $0 |
| Apr 3, 2024 | Schallenberger Mark A. | Chief Operations Officer | Grant(A) | 173K | — | $0 |
| Apr 3, 2024 | Neils Scott C | Chief Financial Officer | Grant(A) | 178K | — | $0 |
| Apr 3, 2024 | Browne Sean E | President and CEO, Director | Grant(A) | 732K | — | $0 |
| Apr 3, 2024 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 184K | — | $0 |
| Jan 16, 2024 | Neils Scott C | Chief Financial Officer | Tax withholding(F) | 8K | $1.09 | $9K |
| Nov 17, 2023 | Brandt Kevin D | Chief Commercial Officer | Buy(P) | 42K | $1.20 | $50K |
| Oct 15, 2023 | Browne Sean E | President and CEO, Director | Tax withholding(F) | 105K | $1.08 | $114K |
| Aug 15, 2023 | Bakewell John K | Director | Grant(A) | 145K | — | $0 |
| Aug 15, 2023 | Bakewell John K | Director | Grant(A) | 28K | — | $0 |
| Aug 15, 2023 | Beeson Jonn R. | Director | Grant(A) | 145K | — | $0 |
| Aug 15, 2023 | Beeson Jonn R. | Director | Grant(A) | 28K | — | $0 |
| Aug 15, 2023 | McNamara Robert | Director | Grant(A) | 145K | — | $0 |
| Aug 15, 2023 | McNamara Robert | Director | Grant(A) | 28K | — | $0 |
| Aug 15, 2023 | Mitchell-Keller Lori D | Director | Grant(A) | 145K | — | $0 |
| Aug 15, 2023 | Mitchell-Keller Lori D | Director | Grant(A) | 28K | — | $0 |
| Aug 15, 2023 | Vizirgianakis Stavros G. | Director | Grant(A) | 218K | — | $0 |
| Aug 15, 2023 | Vizirgianakis Stavros G. | Director | Grant(A) | 42K | — | $0 |
| Aug 15, 2023 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 120K | — | $0 |
| Aug 15, 2023 | Brandt Kevin D | Chief Commercial Officer | Tax withholding(F) | 50K | $1.18 | $59K |
| Aug 15, 2023 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 141K | — | $0 |
| Aug 15, 2023 | Browne Sean E | President and CEO, Director | Grant(A) | 174K | — | $0 |
| Aug 15, 2023 | Browne Sean E | President and CEO, Director | Grant(A) | 203K | — | $0 |
| Aug 15, 2023 | Neils Scott C | Chief Financial Officer | Grant(A) | 116K | — | $0 |
| Aug 15, 2023 | Neils Scott C | Chief Financial Officer | Tax withholding(F) | 25K | $1.18 | $30K |
| Aug 15, 2023 | Neils Scott C | Chief Financial Officer | Grant(A) | 136K | — | $0 |
| Aug 15, 2023 | Schallenberger Mark A. | Chief Operations Officer | Grant(A) | 116K | — | $0 |
| Aug 15, 2023 | Schallenberger Mark A. | Chief Operations Officer | Grant(A) | 136K | — | $0 |
| Jun 15, 2023 | Mitchell-Keller Lori D | Director | Grant(A) | 46K | — | $0 |
| May 15, 2023 | Beeson Jonn R. | Director | Grant(A) | 52K | — | $0 |
| Feb 15, 2023 | Schallenberger Mark A. | Chief Operations Officer | Grant(A) | 89K | — | $0 |
| Feb 15, 2023 | Schallenberger Mark A. | Chief Operations Officer | Grant(A) | 105K | — | $0 |
| Jan 18, 2023 | Neils Scott C | Chief Financial Officer | Sell(S) | 9K | $0.61 | $5K |
| Nov 15, 2022 | Vizirgianakis Stavros G. | Director | Grant(A) | 145K | — | $0 |
| Oct 19, 2022 | Browne Sean E | President and CEO, Director | Sell(S) | 51K | $0.62 | $32K |
| Oct 18, 2022 | Browne Sean E | President and CEO, Director | Sell(S) | 80K | $0.68 | $54K |
| Oct 7, 2022 | Vizirgianakis Stavros G. | Director | Buy(P) | 2.3M | $0.48 | $1.1M |
| Oct 7, 2022 | Vizirgianakis Stavros G. | Director | Buy(P) | 566K | — | $0 |
| Aug 25, 2022 | Vizirgianakis Stavros G. | Director | Grant(A) | 71K | — | $0 |
| Aug 17, 2022 | Neils Scott C | Chief Financial Officer | Sell(S) | 1K | $0.48 | $610 |
| Aug 17, 2022 | Brandt Kevin D | Chief Commercial Officer | Sell(S) | 4K | $0.48 | $2K |
| Aug 16, 2022 | Neils Scott C | Chief Financial Officer | Sell(S) | 5K | $0.48 | $2K |
| Aug 16, 2022 | Brandt Kevin D | Chief Commercial Officer | Sell(S) | 19K | $0.49 | $9K |
| Aug 15, 2022 | Rizzo Matthew | Director, 10% Owner | Grant(A) | 215K | — | $0 |
| Aug 15, 2022 | Eggenberg Michael | Director, 10% Owner | Grant(A) | 215K | — | $0 |
| Aug 15, 2022 | Orbimed Advisors LLC | Director, 10% Owner | Other(J) | 215K | — | $0 |
| Aug 15, 2022 | Orbimed Advisors LLC | Director, 10% Owner | Other(J) | 215K | — | $0 |
| Aug 15, 2022 | Bakewell John K | Director | Grant(A) | 215K | — | $0 |
| Aug 15, 2022 | McNamara Robert | Director | Grant(A) | 215K | — | $0 |
| Aug 15, 2022 | Peters Jeffrey J | Director | Grant(A) | 215K | — | $0 |
| Aug 15, 2022 | Neils Scott C | Chief Financial Officer | Grant(A) | 252K | — | $0 |
| Aug 15, 2022 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 410K | — | $0 |
| Jan 15, 2022 | Neils Scott C | Interim Chief Financial Office | Grant(A) | 109K | — | $0 |
| Jan 15, 2022 | Neils Scott C | Interim Chief Financial Office | Grant(A) | 89K | — | $0 |
| Oct 15, 2021 | Browne Sean E | President and CEO, Director | Tax withholding(F) | 160K | $1.11 | $178K |
| Aug 15, 2021 | Orbimed ROF II LLC | Director, 10% Owner | Other(J) | 85K | — | $0 |
| Aug 15, 2021 | Orbimed ROF II LLC | Director, 10% Owner | Other(J) | 85K | — | $0 |
| Aug 15, 2021 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 200K | — | $0 |
| Aug 15, 2021 | Brandt Kevin D | Chief Commercial Officer | Tax withholding(F) | 7K | $1.20 | $9K |
| Aug 15, 2021 | Brandt Kevin D | Chief Commercial Officer | Grant(A) | 162K | — | $0 |
| Aug 15, 2021 | Bakewell John K | Director | Grant(A) | 85K | — | $0 |
| Aug 15, 2021 | Peters Jeffrey J | Director | Grant(A) | 85K | — | $0 |
| Aug 15, 2021 | McNamara Robert | Director | Grant(A) | 85K | — | $0 |
| Aug 15, 2021 | Eggenberg Michael | Director | Grant(A) | 85K | — | $0 |
| Aug 15, 2021 | Rizzo Matthew | Director | Grant(A) | 85K | — | $0 |
| Aug 15, 2021 | Jensen Greg | Vice President, Finance & CFO | Grant(A) | 192K | — | $0 |
| Aug 15, 2021 | Jensen Greg | Vice President, Finance & CFO | Grant(A) | 156K | — | $0 |
| Jul 9, 2021 | Brandt Kevin D | Chief Commercial Officer | Tax withholding(F) | 9K | $1.74 | $15K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).