PYXS

Pyxis Oncology Inc$3.06 3.38%
Health CareUSCUSIP 747324101· EOD Aug 25, 2026◍ Confluence graph
Tracked 13F Holders
72
-56 QoQ
13F Value (tracked)
$50.4M
Insider Net · 180d
-$107K
0↑ 1↓
Recent Filings
15
Smart-money sentimentBearish
BearishBullish
13F funds (latest Q)12 adding · 15 trimming
Insider net (180d)-$107K

Price & smart-money activity

$3.06 3.38%5Y -76.8%
$0.84$4.18$7.51$10.85$14.18202120222023202420252026222131087843859795766621879131882181613183181613192016152366
Hover for who · click for detailEnd-of-day closing prices52w $1.06 – $5.34

Who owns PYXS?

72 tracked 13F filers

72 tracked 13F filers disclose a position in PYXS as of the latest SEC 13F filings, a combined $50.4M in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

All quarters use one ordinary-share-equivalent series. Historical ADS are converted at 2 ADS = 1 ordinary share. Expand a row for the exact calculation; the residual is not classified as a trade.
#FundPosition valueSharesLast moveAs ofHistory
1PFIZER INC
$15.6M
7.0M
Held
Q3 2025
2Laurion Capital Management LP
$7.3M
5.0M
+4.2%
Added · +201K sh
Q1 2026
3GordonMD Global Investments LP
$6.0M
4.1M
Held
Q1 2026
4VANGUARD CAPITAL MANAGEMENT LLC
$3.0M
2.0M
First observed position
No prior filed position
Q1 2026
5Atle Fund Management AB
$2.9M
966K
+390%
Added · +769K sh
Q2 2026
6RENAISSANCE TECHNOLOGIES LLC
$1.3M
889K
+22%
Added · +160K sh
Q1 2026
7Palo Alto Investors LP
$2.6M
864K
−14%
Reduced · −146K sh
Q2 2026
8BlackRock, Inc.
$1.2M
789K
+0.6%
Added · +5K sh
Q1 2026
9GEODE CAPITAL MANAGEMENT, LLC
$1.8M
592K
−1.0%
Reduced · −6K sh
Q2 2026
10Longaeva Partners L.P.
$735K
503K
Held
Q1 2026
11JACOBS LEVY EQUITY MANAGEMENT, INC
$673K
461K
New
+461K sh
Q1 2026
12683 Capital Management, LLC
$1.4M
459K
−49%
Reduced · −437K sh
Q2 2026
13MILLENNIUM MANAGEMENT LLC
$581K
398K
−46%
Reduced · −345K sh
Q1 2026
14MARSHALL WACE, LLP
$517K
354K
−9.1%
Reduced · −35K sh
Q1 2026
15JANE STREET GROUP, LLC
$445K
304K
−61%
Reduced · −482K sh
Q1 2026
16VANGUARD FIDUCIARY TRUST CO
$439K
301K
First observed position
No prior filed position
Q1 2026
17UBS Group AG
$371K
254K
−35%
Reduced · −139K sh
Q1 2026
18STATE STREET CORP
$749K
249K
Held
Q2 2026
19XTX Topco Ltd
$292K
200K
−31%
Reduced · −89K sh
Q1 2026
20Bank of New York Mellon Corp
$196K
134K
−19%
Reduced · −31K sh
Q1 2026
21NewEdge Wealth, LLC
$349K
116K
Held
Q2 2026
22NORTHERN TRUST CORP
$149K
102K
Held
Q1 2026
23BRIDGEWAY CAPITAL MANAGEMENT, LLC
$119K
81K
+12%
Added · +9K sh
Q1 2026
24TWO SIGMA INVESTMENTS, LP
$107K
73K
−31%
Reduced · −32K sh
Q1 2026
25MORGAN STANLEY
$102K
70K
−22%
Reduced · −20K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Is PYXS being bought or sold by institutions?

Last quarter, 3 funds opened a new position in PYXS and 9 added to an existing one, while 15 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).

Opened (NEW)
3
funds
Added
9
funds
Reduced
15
funds
Exited
0
funds

Funds that own PYXS also own

CompanyCo-held byCombined value
NVIDIA CORPNVDA29 funds$21.9B
AMAZON.COM INCAMZN29 funds$12.9B
ELI LILLY & COLLY28 funds$3.2B
MICROSOFT CORPMSFT27 funds$11.0B
META PLATFORMS INC-CLASS AMETA27 funds$7.4B
ALPHABET INC-CL CGOOG27 funds$5.1B
COSTCO WHOLESALE CORPCOST27 funds$3.7B
UNITEDHEALTH GROUP INCUNH27 funds$3.0B
BRISTOL-MYERS SQUIBB COBMY27 funds$1.9B
ALPHABET INC-CL AGOOGL26 funds$9.9B
MICRON TECHNOLOGY INCMU26 funds$7.5B
PALANTIR TECHNOLOGIES INC-APLTR26 funds$3.8B

Ranked by how many of PYXS's institutional holders also hold each name, a cross-fund conviction signal.

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$107K
1 insiders
Net
-$107K
1 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jun 30, 2026Dupont JakobDirectorSell (S)35K$107K
Apr 21, 2025HUMPHREY RACHELDirectorSell (S)14K$14K
Apr 17, 2025HUMPHREY RACHELDirectorSell (S)200$194
Apr 14, 2025HUMPHREY RACHELDirectorSell (S)1K$1K
Nov 26, 2024Connealy Pamela AnnCFO & COOBuy (P)5K$11K
Nov 26, 2024Connealy Pamela AnnCFO & COOBuy (P)83K$163K
Sep 28, 2023Connealy Pamela AnnCFO and COOBuy (P)8K$15K
Sep 27, 2023Connealy Pamela AnnCFO and COOBuy (P)6K$12K
Sep 27, 2023Wadhane JitendraChief Accounting OfficerBuy (P)3K$5K
Sep 25, 2023Connealy Pamela AnnCFO and COOBuy (P)12K$20K
Sep 25, 2023Wadhane JitendraChief Accounting OfficerBuy (P)5K$9K
Sep 22, 2023Connealy Pamela AnnCFO and COOBuy (P)5K$9K

Institutional ownership over time

15 funds-59 since Q3 2024
04079Q3 2024Q1 2025Q3 2025Q1 2026Q2 2026
funds holding aggregate valuelatest $4.4M

Recent filings

15 shown

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Connected entities for PYXS

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Ask your agent what changed in PYXS

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/PYXS/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for PYXS.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for PYXS. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.