The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Feb 9, 2026 | Fairmount Healthcare Fund II L.P. | 10% Owner | Option exercise(M) | 5.8M | — | $0 |
| Feb 9, 2026 | Fairmount Healthcare Fund II L.P. | 10% Owner | Option exercise(M) | 2.9M | — | $0 |
| Feb 9, 2026 | Fairmount Healthcare Fund II L.P. | 10% Owner | Option exercise(M) | 6K | — | $0 |
| Feb 9, 2026 | Fairmount Healthcare Fund II L.P. | 10% Owner | Option exercise(M) | 3K | — | $0 |
| Feb 9, 2026 | Bruno Julianne | Director | Option exercise(M) | 129K | — | $0 |
| Feb 9, 2026 | Bruno Julianne | Director | Option exercise(M) | 129 | — | $0 |
| Jan 5, 2026 | Hewes L. Becker | Chief Medical Officer | Grant(A) | 265K | — | $0 |
| Jan 5, 2026 | Hewes L. Becker | Chief Medical Officer | Grant(A) | 529K | — | $0 |
| Jan 5, 2026 | Sattarzadeh Sherwin | Chief Operating Officer | Grant(A) | 190K | — | $0 |
| Jan 5, 2026 | Sattarzadeh Sherwin | Chief Operating Officer | Grant(A) | 444K | — | $0 |
| Jan 2, 2026 | Firmani Lori | Chief Financial Officer | Option exercise(M) | 374 | — | — |
| Jan 2, 2026 | Firmani Lori | Chief Financial Officer | Sell(S) | 135 | $21.41 | $3K |
| Jan 2, 2026 | Firmani Lori | Chief Financial Officer | Option exercise(M) | 374 | — | $0 |
| Jan 2, 2026 | Winslow Garrett | General Counsel | Sell(S) | 255 | $21.38 | $5K |
| Jan 2, 2026 | Winslow Garrett | General Counsel | Option exercise(M) | 680 | — | — |
| Jan 2, 2026 | Winslow Garrett | General Counsel | Option exercise(M) | 680 | — | $0 |
| Jan 2, 2026 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 1K | — | — |
| Jan 2, 2026 | Schambye Hans T. | Chief Executive Officer, Director | Sell(S) | 700 | $21.38 | $15K |
| Jan 2, 2026 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 1K | — | $0 |
| Jul 3, 2025 | Firmani Lori | Interim CFO | Option exercise(M) | 374 | — | — |
| Jul 3, 2025 | Firmani Lori | Interim CFO | Sell(S) | 147 | $3.39 | $498 |
| Jul 3, 2025 | Firmani Lori | Interim CFO | Option exercise(M) | 374 | — | $0 |
| Jul 3, 2025 | Winslow Garrett | General Counsel | Option exercise(M) | 680 | — | — |
| Jul 3, 2025 | Winslow Garrett | General Counsel | Sell(S) | 260 | $3.39 | $881 |
| Jul 3, 2025 | Winslow Garrett | General Counsel | Option exercise(M) | 680 | — | $0 |
| Jul 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Sell(S) | 735 | $3.38 | $2K |
| Jul 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 1K | — | — |
| Jul 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 1K | — | $0 |
| Jun 18, 2025 | Goldfischer Carl | Director | Grant(A) | 1K | — | $0 |
| Jun 18, 2025 | Wechsler Amy B | Director | Grant(A) | 720 | — | $0 |
| Jun 18, 2025 | Prener Anne | Director | Grant(A) | 720 | — | $0 |
| Jun 18, 2025 | Shapiro David | Director | Grant(A) | 720 | — | $0 |
| Jun 18, 2025 | Munshi Amit | Director | Grant(A) | 720 | — | $0 |
| Jun 18, 2025 | Dallas Jayson Donald Alexander | Director | Grant(A) | 720 | — | $0 |
| Jan 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 3K | — | — |
| Jan 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Sell(S) | 1K | $5.60 | $8K |
| Jan 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Grant(A) | 16K | — | $0 |
| Jan 3, 2025 | Schambye Hans T. | Chief Executive Officer, Director | Option exercise(M) | 3K | — | $0 |
| Jan 3, 2025 | Kronmiller Matthew | EVP Strategy and CBO | Grant(A) | 6K | — | $0 |
| Jan 3, 2025 | Firmani Lori | Interim CFO | Option exercise(M) | 726 | — | — |
| Jan 3, 2025 | Firmani Lori | Interim CFO | Sell(S) | 261 | $5.63 | $1K |
| Jan 3, 2025 | Firmani Lori | Interim CFO | Option exercise(M) | 726 | — | $0 |
| Jan 3, 2025 | Firmani Lori | Interim CFO | Grant(A) | 5K | — | $0 |
| Jan 3, 2025 | Winslow Garrett | General Counsel | Option exercise(M) | 1K | — | — |
| Jan 3, 2025 | Winslow Garrett | General Counsel | Sell(S) | 471 | $5.60 | $3K |
| Jan 3, 2025 | Winslow Garrett | General Counsel | Option exercise(M) | 1K | — | $0 |
| Jan 3, 2025 | Winslow Garrett | General Counsel | Grant(A) | 6K | — | $0 |
| Oct 11, 2024 | Wechsler Amy B | Director | Grant(A) | 480 | — | $0 |
| Oct 11, 2024 | Wechsler Amy B | Director | Grant(A) | 720 | — | $0 |
| Oct 9, 2024 | Schambye Hans T. | Chief Executive Officer, Director | Grant(A) | 44K | — | $0 |
| Oct 9, 2024 | Firmani Lori | Interim CFO | Grant(A) | 13K | — | $0 |
| Oct 9, 2024 | Kronmiller Matthew | EVP Strategy and CBO | Grant(A) | 9K | — | $0 |
| Oct 9, 2024 | Winslow Garrett | General Counsel | Grant(A) | 16K | — | $0 |
| Jun 20, 2024 | Dallas Jayson Donald Alexander | Director | Grant(A) | 18K | — | $0 |
| Jun 20, 2024 | Shapiro David | Director | Grant(A) | 18K | — | $0 |
| Jun 20, 2024 | Goldfischer Carl | Director | Grant(A) | 36K | — | $0 |
| Jun 20, 2024 | Munshi Amit | Director | Grant(A) | 18K | — | $0 |
| Jun 20, 2024 | Prener Anne | Director | Grant(A) | 18K | — | $0 |
| Jan 3, 2024 | Winslow Garrett | General Counsel | Grant(A) | 100K | — | $0 |
| Jan 3, 2024 | Freve Jonathan | Chief Financial Officer | Grant(A) | 100K | — | $0 |
| Jan 3, 2024 | Schambye Hans T. | Chief Executive Officer, Director | Grant(A) | 200K | — | $0 |
| Aug 15, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 536K | $0.75 | $402K |
| Aug 15, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 38K | $0.75 | $29K |
| Aug 15, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 249K | $0.75 | $187K |
| Jul 31, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 27K | $3.00 | $80K |
| Jul 31, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 30K | $3.00 | $89K |
| Jul 31, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 153K | $3.00 | $459K |
| Jul 25, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 27K | $2.92 | $78K |
| Jul 25, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 8K | $2.92 | $23K |
| Jul 25, 2023 | OrbiMed Capital GP VII LLC | 10% Owner | Sell(S) | 5K | $2.92 | $14K |
| Jul 13, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 10K | $2.40 | $24K |
| Jul 13, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 132K | $2.40 | $317K |
| Jul 13, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 53K | $2.40 | $127K |
| Jun 17, 2023 | Dallas Jayson Donald Alexander | Director | Grant(A) | 18K | — | $0 |
| Jun 14, 2023 | Khuong Chau Quang | Director | Grant(A) | 18K | — | $0 |
| Jun 14, 2023 | Goldfischer Carl | Director | Grant(A) | 36K | — | $0 |
| Jun 14, 2023 | Munshi Amit | Director | Grant(A) | 18K | — | $0 |
| Jun 14, 2023 | Prener Anne | Director | Grant(A) | 18K | — | $0 |
| Jun 14, 2023 | Shapiro David | Director | Grant(A) | 18K | — | $0 |
| Apr 17, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 4K | $1.97 | $7K |
| Apr 17, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 9K | $1.97 | $17K |
| Apr 17, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 660 | $1.97 | $1K |
| Apr 14, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 2K | $1.86 | $4K |
| Apr 14, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 11K | $1.86 | $21K |
| Apr 14, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 28K | $1.86 | $52K |
| Apr 13, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 9K | $1.82 | $17K |
| Apr 13, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 4K | $1.82 | $7K |
| Apr 13, 2023 | Orbimed Advisors LLC | 10% Owner | Sell(S) | 703 | $1.82 | $1K |
| Apr 12, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 2K | $1.81 | $3K |
| Apr 12, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 119 | $1.81 | $215 |
| Apr 12, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 641 | $1.81 | $1K |
| Apr 11, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 9K | $1.82 | $17K |
| Apr 11, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 703 | $1.82 | $1K |
| Apr 11, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 4K | $1.82 | $7K |
| Apr 10, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 3K | $1.79 | $5K |
| Apr 10, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 14K | $1.79 | $25K |
| Apr 10, 2023 | OrbiMed Advisors Israel II Ltd | 10% Owner | Sell(S) | 35K | $1.79 | $62K |
| Apr 6, 2023 | OrbiMed Genesis GP LLC | 10% Owner | Sell(S) | 7K | $2.00 | $13K |
| Apr 6, 2023 | OrbiMed Genesis GP LLC | 10% Owner | Sell(S) | 3K | $2.00 | $5K |
| Apr 6, 2023 | OrbiMed Genesis GP LLC | 10% Owner | Sell(S) | 487 | $2.00 | $974 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-14. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).