The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 7, 2026 | Ruiz Briseno Andres | Chief Accounting Officer | Option exercise(M) | 10K | — | $0 |
| Jul 7, 2026 | Ruiz Briseno Andres | Chief Accounting Officer | Sell(S) | 10K | $40.01 | $382K |
| Jul 7, 2026 | Ruiz Briseno Andres | Chief Accounting Officer | Option exercise(M) | 10K | $12.86 | $123K |
| Jun 16, 2026 | Morrison Scott W | Director | Grant(A) | 20K | — | $0 |
| Jun 16, 2026 | Yarno Wendy L | Director | Grant(A) | 20K | — | $0 |
| Jun 16, 2026 | Stein Jeffrey | Director | Grant(A) | 20K | — | $0 |
| Jun 16, 2026 | Rosen Terry J | Director | Grant(A) | 20K | — | $0 |
| Jun 16, 2026 | Mackey Catherine J | Director | Grant(A) | 20K | — | $0 |
| Jun 16, 2026 | Hampton Malcolm Garret | Director | Grant(A) | 20K | — | $0 |
| Mar 2, 2026 | Stein Jeffrey | Director | Buy(P) | 50K | $32.96 | $1.6M |
| Jan 30, 2026 | Ruiz Briseno Andres | See Remarks | Grant(A) | 80K | — | $0 |
| Jan 30, 2026 | Snyder Douglas B. | SVP, General Counsel | Grant(A) | 130K | — | $0 |
| Jan 30, 2026 | Hata Yujiro S | President and CEO, Director | Grant(A) | 600K | — | $0 |
| Jan 30, 2026 | Dorman Stuart | Chief Commercial Officer | Grant(A) | 155K | — | $0 |
| Jan 30, 2026 | Beaupre Darrin | Chief Medical Officer | Grant(A) | 175K | — | $0 |
| Jan 30, 2026 | White Michael Anthony | Chief Scientific Officer | Grant(A) | 190K | — | $0 |
| Jan 30, 2026 | Bleharski Joshua | Chief Financial Officer | Grant(A) | 170K | — | $0 |
| Nov 28, 2025 | Ruiz Briseno Andres | See Remarks | Grant(A) | 1K | $16.91 | $21K |
| Nov 28, 2025 | Snyder Douglas B. | SVP, General Counsel | Grant(A) | 1K | $16.91 | $18K |
| Jun 24, 2025 | Rosen Terry J | Director | Grant(A) | 20K | — | $0 |
| Jun 24, 2025 | Mackey Catherine J | Director | Grant(A) | 20K | — | $0 |
| Jun 24, 2025 | Morrison Scott W | Director | Grant(A) | 20K | — | $0 |
| Jun 24, 2025 | Hampton Malcolm Garret | Director | Grant(A) | 20K | — | $0 |
| Jun 24, 2025 | Stein Jeffrey | Director | Grant(A) | 20K | — | $0 |
| Jun 24, 2025 | Yarno Wendy L | Director | Grant(A) | 20K | — | $0 |
| May 30, 2025 | Snyder Douglas B. | SVP, General Counsel | Grant(A) | 1K | $16.91 | $18K |
| Feb 27, 2025 | Hata Yujiro S | President and CEO, Director | Grant(A) | 600K | — | $0 |
| Feb 27, 2025 | Snyder Douglas B. | SVP, General Counsel | Grant(A) | 33K | — | $0 |
| Feb 27, 2025 | White Michael Anthony | Chief Scientific Officer | Grant(A) | 185K | — | $0 |
| Feb 27, 2025 | Ruiz Briseno Andres | See Remarks | Grant(A) | 75K | — | $0 |
| Feb 27, 2025 | Dorman Stuart | Chief Commercial Officer | Grant(A) | 15K | — | $0 |
| Feb 27, 2025 | Beaupre Darrin | Chief Medical Officer | Grant(A) | 185K | — | $0 |
| Feb 18, 2025 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 13K | $19.52 | $250K |
| Feb 18, 2025 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 13K | — | $0 |
| Nov 29, 2024 | Ruiz Briseno Andres | See Remarks | Grant(A) | 682 | $23.26 | $16K |
| Sep 26, 2024 | Snyder Douglas B. | SVP, General Counsel | Grant(A) | 140K | — | $0 |
| Jun 27, 2024 | Throne Jason | Chief Legal Officer | Option exercise(M) | 47K | $7.01 | $330K |
| Jun 27, 2024 | Throne Jason | Chief Legal Officer | Option exercise(M) | 6K | $13.34 | $86K |
| Jun 27, 2024 | Throne Jason | Chief Legal Officer | Option exercise(M) | 6K | — | $0 |
| Jun 27, 2024 | Throne Jason | Chief Legal Officer | Option exercise(M) | 47K | — | $0 |
| May 31, 2024 | Mackey Catherine J | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Yarno Wendy L | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Morrison Scott W | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Stein Jeffrey | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Hampton Malcolm Garret | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Kelley Susan L. | Director | Grant(A) | 16K | — | $0 |
| May 31, 2024 | Rosen Terry J | Director | Grant(A) | 16K | — | $0 |
| May 29, 2024 | White Michael Anthony | Chief Scientific Officer | Sell(S) | 28K | $36.23 | $1.0M |
| May 29, 2024 | White Michael Anthony | Chief Scientific Officer | Option exercise(M) | 29K | $12.86 | $367K |
| May 29, 2024 | White Michael Anthony | Chief Scientific Officer | Sell(S) | 851 | $36.78 | $31K |
| May 29, 2024 | White Michael Anthony | Chief Scientific Officer | Option exercise(M) | 29K | — | $0 |
| May 16, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 4K | $42.37 | $184K |
| May 16, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 34K | $4.31 | $148K |
| May 16, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 30K | $41.73 | $1.3M |
| May 16, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 34K | — | $0 |
| May 15, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 54K | $42.57 | $2.3M |
| May 15, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 30K | $43.48 | $1.3M |
| May 15, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 503 | $44.12 | $22K |
| May 15, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 84K | $4.31 | $361K |
| May 15, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 84K | — | $0 |
| May 14, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 57K | $4.31 | $244K |
| May 14, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 54K | $41.60 | $2.3M |
| May 14, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 2K | $41.84 | $96K |
| May 14, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 57K | — | $0 |
| Mar 1, 2024 | Throne Jason | Chief Legal Officer | Grant(A) | 126K | — | $0 |
| Mar 1, 2024 | White Michael Anthony | Chief Scientific Officer | Grant(A) | 140K | — | $0 |
| Mar 1, 2024 | Beaupre Darrin | Chief Medical Officer | Grant(A) | 160K | — | $0 |
| Mar 1, 2024 | Ruiz Briseno Andres | See Remarks | Grant(A) | 85K | — | $0 |
| Mar 1, 2024 | Hata Yujiro S | President and CEO, Director | Grant(A) | 480K | — | $0 |
| Feb 9, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 24K | $4.31 | $102K |
| Feb 9, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 24K | $45.54 | $1.1M |
| Feb 9, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 24K | — | $0 |
| Feb 9, 2024 | Ruiz Briseno Andres | See Remarks | Sell(S) | 2K | $46.02 | $92K |
| Feb 8, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 76K | $4.31 | $327K |
| Feb 8, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 76K | $45.15 | $3.4M |
| Feb 8, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 76K | — | $0 |
| Feb 1, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 628 | $4.31 | $3K |
| Feb 1, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 4 | $45.01 | $180 |
| Feb 1, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 624 | $45.00 | $28K |
| Feb 1, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 628 | — | $0 |
| Jan 22, 2024 | Ruiz Briseno Andres | See Remarks | Sell(S) | 2K | $42.03 | $84K |
| Jan 16, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 63K | $4.31 | $270K |
| Jan 16, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 63K | $40.17 | $2.5M |
| Jan 16, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 63K | — | $0 |
| Jan 12, 2024 | Hata Yujiro S | President and CEO, Director | Sell(S) | 12K | $40.04 | $491K |
| Jan 12, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 12K | $4.31 | $53K |
| Jan 12, 2024 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 12K | — | $0 |
| Jan 12, 2024 | Ruiz Briseno Andres | See Remarks | Sell(S) | 2K | $38.01 | $76K |
| Dec 18, 2023 | Throne Jason | Chief Legal Officer | Option exercise(M) | 10K | $7.01 | $70K |
| Dec 18, 2023 | Throne Jason | Chief Legal Officer | Option exercise(M) | 10K | — | $0 |
| Dec 15, 2023 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 75K | $4.31 | $323K |
| Dec 15, 2023 | Hata Yujiro S | President and CEO, Director | Sell(S) | 75K | $35.03 | $2.6M |
| Dec 15, 2023 | Hata Yujiro S | President and CEO, Director | Option exercise(M) | 75K | — | $0 |
| Dec 15, 2023 | Throne Jason | Chief Legal Officer | Sell(S) | 10K | $35.04 | $350K |
| Dec 15, 2023 | Throne Jason | Chief Legal Officer | Option exercise(M) | 10K | $13.34 | $133K |
| Dec 15, 2023 | Throne Jason | Chief Legal Officer | Option exercise(M) | 10K | — | $0 |
| Dec 14, 2023 | Ruiz Briseno Andres | See Remarks | Sell(S) | 328 | $34.01 | $11K |
| Dec 14, 2023 | Ruiz Briseno Andres | See Remarks | Sell(S) | 2K | $34.00 | $57K |
| Nov 3, 2023 | Throne Jason | Chief Legal Officer | Option exercise(M) | 5K | $12.86 | $66K |
| Nov 3, 2023 | Throne Jason | Chief Legal Officer | Sell(S) | 5K | $30.09 | $155K |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-04-26 → 2026-07-11. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).