The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jun 3, 2026 | Debbane Raymond | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Debbane Raymond | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Amouyal Philippe | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Amouyal Philippe | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Cheung Ivan | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Cheung Ivan | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Barker Sam L | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Barker Sam L | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Sullivan Diane E. | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Sullivan Diane E. | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Sobecki Christopher J | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Sobecki Christopher J | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Swain Judith L | Director | Option exercise(M) | 89K | — | $0 |
| Jun 3, 2026 | Swain Judith L | Director | Option exercise(M) | 89K | — | $0 |
| May 1, 2026 | Sobecki Christopher J | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Sobecki Christopher J | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Swain Judith L | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Swain Judith L | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Sullivan Diane E. | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Sullivan Diane E. | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Debbane Raymond | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Debbane Raymond | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Cheung Ivan | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Cheung Ivan | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Barker Sam L | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Amouyal Philippe | Director | Grant(A) | 43K | — | $0 |
| May 1, 2026 | Amouyal Philippe | Director | Grant(A) | 36K | — | $0 |
| May 1, 2026 | Barker Sam L | Director | Grant(A) | 36K | — | $0 |
| Apr 30, 2026 | Artal Participations S.a r.l. | Director, 10% Owner | Option exercise(M) | 408K | — | $0 |
| Apr 30, 2026 | Artal Participations S.a r.l. | Director, 10% Owner | Grant(A) | 408K | — | — |
| Apr 30, 2026 | Artal Participations S.a r.l. | Director, 10% Owner | Option exercise(M) | 20.4M | — | $0 |
| Feb 28, 2026 | Exton Michael | Chief Executive Officer, Director | Tax withholding(F) | 205K | $1.47 | $301K |
| Feb 28, 2026 | Exton Michael | Chief Executive Officer, Director | Option exercise(M) | 503K | — | — |
| Feb 28, 2026 | Exton Michael | Chief Executive Officer, Director | Option exercise(M) | 503K | — | — |
| Feb 28, 2026 | Coiante Scott M | SVP, Chief Financial Officer | Option exercise(M) | 160K | — | — |
| Feb 28, 2026 | Coiante Scott M | SVP, Chief Financial Officer | Tax withholding(F) | 55K | $1.47 | $81K |
| Feb 28, 2026 | Coiante Scott M | SVP, Chief Financial Officer | Option exercise(M) | 160K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 170K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 33K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Tax withholding(F) | 105K | $1.47 | $154K |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 69K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 170K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 69K | — | — |
| Feb 28, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Option exercise(M) | 33K | — | — |
| Feb 28, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Tax withholding(F) | 75K | $1.47 | $110K |
| Feb 28, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Option exercise(M) | 128K | — | — |
| Feb 28, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Option exercise(M) | 25K | — | — |
| Feb 28, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Option exercise(M) | 25K | — | — |
| Feb 28, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Option exercise(M) | 128K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 66K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Tax withholding(F) | 24K | $1.47 | $36K |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 20K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 14K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 14K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 20K | — | — |
| Feb 28, 2026 | Gopinathan Suma | SVP, Discovery | Option exercise(M) | 66K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 36K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 74K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Tax withholding(F) | 109K | $1.47 | $160K |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 202K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 74K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 36K | — | — |
| Feb 28, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Option exercise(M) | 202K | — | — |
| Feb 28, 2026 | Martens Rachel Yap | SVP, Partnerships & Corp Strat | Tax withholding(F) | 36K | $1.47 | $53K |
| Feb 28, 2026 | Martens Rachel Yap | SVP, Partnerships & Corp Strat | Option exercise(M) | 67K | — | — |
| Feb 28, 2026 | Martens Rachel Yap | SVP, Partnerships & Corp Strat | Option exercise(M) | 67K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 52K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 28K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 144K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Tax withholding(F) | 68K | $1.47 | $100K |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 52K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 144K | — | — |
| Feb 28, 2026 | McDermott Wendy | SVP, Human Resources | Option exercise(M) | 28K | — | — |
| Feb 25, 2026 | Debbane Raymond | Director | Buy(P) | 2K | $1.49 | $3K |
| Feb 23, 2026 | Debbane Raymond | Director | Buy(P) | 100K | $1.47 | $147K |
| Feb 20, 2026 | Debbane Raymond | Director | Buy(P) | 100K | $1.48 | $148K |
| Feb 19, 2026 | Debbane Raymond | Director | Buy(P) | 50K | $1.44 | $72K |
| Feb 18, 2026 | Debbane Raymond | Director | Buy(P) | 134K | $1.32 | $176K |
| Feb 17, 2026 | Debbane Raymond | Director | Buy(P) | 77K | $1.31 | $101K |
| Feb 17, 2026 | Artal International S.C.A. | Director, 10% Owner | Grant(A) | 41K | $65.00 | $2.7M |
| Feb 13, 2026 | Debbane Raymond | Director | Buy(P) | 58K | $1.31 | $76K |
| Feb 12, 2026 | Exton Michael | Chief Executive Officer, Director | Grant(A) | 862K | — | $0 |
| Feb 12, 2026 | Exton Michael | Chief Executive Officer, Director | Grant(A) | 1.3M | — | $0 |
| Feb 12, 2026 | Coiante Scott M | SVP, Chief Financial Officer | Grant(A) | 409K | — | $0 |
| Feb 12, 2026 | Coiante Scott M | SVP, Chief Financial Officer | Grant(A) | 273K | — | $0 |
| Feb 12, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Grant(A) | 450K | — | $0 |
| Feb 12, 2026 | Crum Brian T | SVP, General Counsel & Secr. | Grant(A) | 300K | — | $0 |
| Feb 12, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Grant(A) | 258K | — | $0 |
| Feb 12, 2026 | DeFrancesco Lisa | SVP, IR and Corp Comm | Grant(A) | 386K | — | $0 |
| Feb 12, 2026 | Gopinathan Suma | SVP, Discovery | Grant(A) | 358K | — | $0 |
| Feb 12, 2026 | Gopinathan Suma | SVP, Discovery | Grant(A) | 238K | — | $0 |
| Feb 12, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Grant(A) | 347K | — | $0 |
| Feb 12, 2026 | Granowitz Craig B | SVP, Chief Medical Officer | Grant(A) | 520K | — | $0 |
| Feb 12, 2026 | Martens Rachel Yap | SVP, Partnerships & Corp Strat | Grant(A) | 291K | — | $0 |
| Feb 12, 2026 | Martens Rachel Yap | SVP, Partnerships & Corp Strat | Grant(A) | 194K | — | $0 |
| Feb 12, 2026 | McDermott Wendy | SVP, Human Resources | Grant(A) | 375K | — | $0 |
| Feb 12, 2026 | McDermott Wendy | SVP, Human Resources | Grant(A) | 250K | — | $0 |
| Feb 2, 2026 | Artal Group S.A. | Director, 10% Owner | Buy(P) | 1.5M | $1.30 | $2.0M |
| Feb 2, 2026 | Artal Group S.A. | Director, 10% Owner | Grant(A) | 3.8M | $1.30 | $5.0M |
| Feb 2, 2026 | Artal Group S.A. | Director, 10% Owner | Grant(A) | 18.6M | $1.30 | $24.1M |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-20. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).