Arkolith/Insider Trading/SPRO

SPRO Insider Trading

Spero Therapeutics, Inc. · full profile →Last filing Aug 3, 2026

Filings under SPRO by SmartPros Ltd. (CIK 0001289863) from May 13, 2008 to Mar 5, 2015 belong to a different issuer and are not shown.

Net Selling · 180d
Open-Market Buys (180d)
$0
0 insiders
Open-Market Sells (180d)
$63K
1 insiders
Net Insider Flow
-$63K
open market, 180d
Reporting Insiders
1
1 P/S transactions
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Build on these Form 4 transactions

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Recent Form 4 Transactions

100 shown
DateInsiderRoleActionSharesPriceValue
Aug 3, 2026Zack DebraChief Medical OfficerGrant(A)162K—$0
Aug 3, 2026Zack DebraChief Medical OfficerGrant(A)325K—$0
Jun 23, 2026Deshpande MilindDirectorGrant(A)10K—$0
Jun 23, 2026Deshpande MilindDirectorGrant(A)20K—$0
Jun 23, 2026Jackson Scott ThomasDirectorGrant(A)10K—$0
Jun 23, 2026Jackson Scott ThomasDirectorGrant(A)20K—$0
Jun 23, 2026Smith CynthiaDirectorGrant(A)10K—$0
Jun 23, 2026Smith CynthiaDirectorGrant(A)20K—$0
Jun 23, 2026Thomas Frank EDirectorGrant(A)10K—$0
Jun 23, 2026Thomas Frank EDirectorGrant(A)20K—$0
Jun 23, 2026Vink Patrick V.J.J.DirectorGrant(A)10K—$0
Jun 23, 2026Vink Patrick V.J.J.DirectorGrant(A)20K—$0
Jun 23, 2026Tregoning KathleenDirectorGrant(A)10K—$0
Jun 23, 2026Tregoning KathleenDirectorGrant(A)20K—$0
Jun 23, 2026Pottage John C JrDirectorGrant(A)10K—$0
Jun 23, 2026Pottage John C JrDirectorGrant(A)20K—$0
May 4, 2026Rajavelu EstherSee RemarksSell(S)25K$2.51$63K
Feb 6, 2026Keutzer TimothyChief Operating OfficerSell(S)19K$2.36$44K
Feb 6, 2026Rajavelu EstherSee RemarksSell(S)37K$2.36$88K
Feb 6, 2026Rajavelu EstherSee RemarksSell(S)51K$2.36$120K
Feb 4, 2026Keutzer TimothyChief Operating OfficerSell(S)3K$2.24$8K
Feb 3, 2026Keutzer TimothyChief Operating OfficerSell(S)24K$2.14$52K
Feb 2, 2026Rajavelu EstherSee RemarksSell(S)18K$2.20$41K
Feb 2, 2026Rajavelu EstherSee RemarksGrant(A)249K—$0
Feb 2, 2026Rajavelu EstherSee RemarksGrant(A)498K—$0
Feb 2, 2026Keutzer TimothyChief Operating OfficerSell(S)19K$2.20$42K
Feb 2, 2026Keutzer TimothyChief Operating OfficerGrant(A)68K—$0
Feb 2, 2026Keutzer TimothyChief Operating OfficerGrant(A)137K—$0
Nov 7, 2025Rajavelu EstherSee RemarksSell(S)40K$2.37$95K
Aug 28, 2025Keutzer TimothyChief Operating OfficerSell(S)2K$1.97$3K
Aug 28, 2025Mahadevia AnkitDirectorSell(S)7K$1.97$13K
Jun 12, 2025Tregoning KathleenDirectorGrant(A)20K—$0
Jun 12, 2025Thomas Frank EDirectorGrant(A)20K—$0
Jun 12, 2025Smith CynthiaDirectorGrant(A)20K—$0
Jun 12, 2025Pottage John C JrDirectorGrant(A)20K—$0
Jun 12, 2025Vink Patrick V.J.J.DirectorGrant(A)20K—$0
Jun 12, 2025Jackson Scott ThomasDirectorGrant(A)20K—$0
Jun 12, 2025Deshpande MilindDirectorGrant(A)20K—$0
Jun 12, 2025Mahadevia AnkitDirectorGrant(A)20K—$0
May 2, 2025Rajavelu EstherSee RemarksGrant(A)185K—$0
Feb 5, 2025Mahadevia AnkitDirectorSell(S)14K$0.78$11K
Feb 5, 2025Mahadevia AnkitDirectorSell(S)55K$0.78$43K
Feb 5, 2025Shukla SathCEO & PresidentSell(S)106K$0.78$83K
Feb 5, 2025Shukla SathCEO & PresidentSell(S)43K$0.78$33K
Feb 5, 2025Shukla SathCEO & PresidentSell(S)6K$0.78$5K
Feb 5, 2025Rajavelu EstherCFO & CBOSell(S)21K$0.78$16K
Feb 5, 2025Keutzer TimothyChief Operating OfficerSell(S)25K$0.78$19K
Feb 5, 2025Keutzer TimothyChief Operating OfficerSell(S)28K$0.78$22K
Feb 5, 2025Keutzer TimothyChief Operating OfficerSell(S)4K$0.78$3K
Feb 3, 2025Shukla SathCEO & PresidentGrant(A)751K—$0
Feb 3, 2025Rajavelu EstherCFO & CBOGrant(A)100K—$0
Feb 3, 2025Rajavelu EstherCFO & CBOGrant(A)266K—$0
Feb 3, 2025Keutzer TimothyChief Operating OfficerGrant(A)266K—$0
Nov 8, 2024Rajavelu EstherCFO & CBOSell(S)17K$1.30$22K
Nov 7, 2024Rajavelu EstherCFO & CBOSell(S)23K$1.31$31K
Aug 27, 2024Shukla SathCEO & PresidentSell(S)3K$1.35$4K
Aug 27, 2024Keutzer TimothyChief Operating OfficerSell(S)2K$1.35$3K
Aug 27, 2024Mahadevia AnkitDirectorSell(S)6K$1.35$8K
Aug 5, 2024Shukla SathCEO and PresidentSell(S)18K$1.31$23K
Aug 2, 2024Shukla SathCEO and PresidentSell(S)15K$1.32$20K
May 29, 2024Pottage John C JrDirectorGrant(A)20K—$0
May 29, 2024Thomas Frank EDirectorGrant(A)20K—$0
May 29, 2024Smith CynthiaDirectorGrant(A)20K—$0
May 29, 2024Vink Patrick V.J.J.DirectorGrant(A)20K—$0
May 29, 2024Tregoning KathleenDirectorGrant(A)20K—$0
May 29, 2024Mahadevia AnkitDirectorGrant(A)20K—$0
May 29, 2024Jackson Scott ThomasDirectorGrant(A)20K—$0
May 29, 2024Deshpande MilindDirectorGrant(A)20K—$0
Feb 5, 2024Shukla SathCEO and President, DirectorSell(S)45K$1.45$65K
Feb 2, 2024Shukla SathCEO and President, DirectorSell(S)31K$1.37$42K
Feb 2, 2024Hamed KamalChief Medical OfficerSell(S)28K$1.37$38K
Feb 2, 2024Joseph Tamara LChief Legal OfficerSell(S)31K$1.37$42K
Feb 2, 2024Mahadevia AnkitDirectorSell(S)64K$1.37$87K
Feb 2, 2024Keutzer TimothyChief Operating OfficerSell(S)31K$1.36$42K
Feb 1, 2024Shukla SathCEO and President, DirectorGrant(A)680K—$0
Feb 1, 2024Rajavelu EstherSee RemarksGrant(A)120K—$0
Feb 1, 2024Hamed KamalChief Medical OfficerGrant(A)240K—$0
Feb 1, 2024Joseph Tamara LChief Legal OfficerGrant(A)240K—$0
Feb 1, 2024Keutzer TimothyChief Operating OfficerGrant(A)240K—$0
Jan 2, 2024Tregoning KathleenDirectorGrant(A)36K$1.12$40K
Nov 13, 2023Rajavelu EstherSee RemarksGrant(A)300K—$0
Oct 5, 2023Mahadevia AnkitDirectorGrant(A)20K—$0
Oct 5, 2023Jackson Scott ThomasDirectorGrant(A)20K—$0
Oct 5, 2023Vink Patrick V.J.J.DirectorGrant(A)20K—$0
Oct 5, 2023Tregoning KathleenDirectorGrant(A)20K—$0
Oct 5, 2023Deshpande MilindDirectorGrant(A)20K—$0
Oct 5, 2023Thomas Frank EDirectorGrant(A)20K—$0
Oct 5, 2023Smith CynthiaDirectorGrant(A)20K—$0
Oct 5, 2023Pottage John C JrDirectorGrant(A)20K—$0
Sep 13, 2023Hamed KamalChief Medical OfficerSell(S)39K$1.27$50K
Aug 29, 2023Shukla SathCEO and President, DirectorSell(S)4K$1.30$5K
Aug 28, 2023Shukla SathCEO and President, DirectorSell(S)2K$1.26$2K
Aug 28, 2023Mahadevia AnkitDirectorSell(S)9K$1.26$11K
Aug 28, 2023Joseph Tamara LChief Legal OfficerSell(S)2K$1.26$2K
Aug 28, 2023Keutzer TimothyChief Development OfficerSell(S)2K$1.26$2K
Aug 1, 2023Shukla SathCEO and President, DirectorGrant(A)266K—$0
Jun 12, 2023Hamed KamalChief Medical OfficerGrant(A)140K—$0
Feb 3, 2023Mahadevia AnkitCEO and President, DirectorSell(S)12K$1.81$22K
Feb 2, 2023Shukla SathChief Financial OfficerSell(S)10K$1.83$17K
Feb 2, 2023Joseph Tamara LChief Legal OfficerSell(S)3K$1.86$6K

Data Source

Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.

Issuer: Spero Therapeutics, Inc., SEC CIK 0001701108. The symbol on a Form 4 is typed by the filer, so this page follows the issuer with the newest filing under SPRO and shows every filing by that issuer. Earlier filings under the same symbol by another issuer are left out.

Coverage: Form 4 filings indexed 2006-01-02 → 2026-09-15. Earlier history is backfilling; this window widens as it deepens.

Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).

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