SPRO

Spero Therapeutics Inc$1.57 7.65%
Health CareUSCUSIP 84833T103· EOD Jul 16, 2026◍ Confluence graph
Tracked 13F Holders
39
-5 QoQ
13F Value (tracked)
$20.2M
Insider Net · 180d
-$457K
0↑ 2↓
Recent Filings
15
Smart-money sentimentMixed
BearishBullish
13F funds (latest Q)9 adding · 3 trimming
Insider net (180d)-$457K

Price & smart-money activity

$1.57 7.65%5Y -88.8%
$0.53$5.52$10.50$15.49$20.47202120222023202420252026123546151341514381291145557658556865858296929772691097810
Hover for who · click for detailEnd-of-day closing prices52w $1.57 – $2.98
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Ask your agent what changed in SPRO

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/SPRO/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for SPRO.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

Top institutional holders

39 tracked 13F filers
#FundPosition valueSharesLast moveAs ofHistory
1VANGUARD CAPITAL MANAGEMENT LLC
$4.2M
1.8M
New
+1.8M sh
Q1 2026
2RENAISSANCE TECHNOLOGIES LLC
$2.8M
1.2M
−7.0%
Reduced · −90K sh
Q1 2026
3Alphabet Inc.
$2.1M
890K
Held
Q1 2026
4TWO SIGMA INVESTMENTS, LP
$2.1M
886K
+138%
Added · +513K sh
Q1 2026
5GEODE CAPITAL MANAGEMENT, LLC
$1.2M
520K
−1.8%
Reduced · −9K sh
Q1 2026
6BlackRock, Inc.
$1.0M
433K
−0.1%
Reduced · −414 sh
Q1 2026
7Anson Funds Management LP
$987K
422K
−32%
Reduced · −203K sh
Q1 2026
8CITADEL ADVISORS LLC
$881K
376K
−5.4%
Reduced · −21K sh
Q1 2026
9SUSQUEHANNA INTERNATIONAL GROUP, LLP
$779K
333K
+13%
Added · +39K sh
Q1 2026
10VANGUARD FIDUCIARY TRUST CO
$618K
264K
New
+264K sh
Q1 2026
11STATE STREET CORP
$503K
215K
+2.2%
Added · +5K sh
Q1 2026
12Ionic Capital Management LLC
$458K
196K
Held
Q1 2026
13Squarepoint Ops LLC
$455K
194K
+63%
Added · +75K sh
Q1 2026
14MARSHALL WACE, LLP
$368K
157K
New
+157K sh
Q1 2026
15NORTHERN TRUST CORP
$283K
121K
Held
Q1 2026
16BRIDGEWAY CAPITAL MANAGEMENT, LLC
$269K
115K
Held
Q1 2026
17JANE STREET GROUP, LLC
$249K
106K
−33%
Reduced · −52K sh
Q1 2026
18Shay Capital LLC
$165K
70K
+17%
Added · +10K sh
Q1 2026
19Point72 Asset Management, L.P.
$140K
60K
+37%
Added · +16K sh
Q1 2026
20Quadrature Capital Ltd
$94K
40K
+6.2%
Added · +2K sh
Q1 2026
21Capital Asset Advisory Services LLC
$92K
33K
Held
Q1 2026
22DLK Investment Management, LLC
$41K
31K
New
+31K sh
Q2 2026
23SIMPLEX TRADING, LLC
$71K
30K
−15%
Reduced · −5K sh
Q1 2026
24DIMENSIONAL FUND ADVISORS LP
$69K
30K
Held
Q1 2026
25CHARLES SCHWAB INVESTMENT MANAGEMENT INC
$67K
29K
Held
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Fund activity: latest quarter

Opened (NEW)
4
funds
Added
5
funds
Reduced
3
funds
Exited
0
funds

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$457K
2 insiders
Net
-$457K
8 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jun 23, 2026Deshpande MilindDirectorGrant (A)10K$0
Jun 23, 2026Deshpande MilindDirectorGrant (A)20K$0
Jun 23, 2026Jackson Scott ThomasDirectorGrant (A)10K$0
Jun 23, 2026Jackson Scott ThomasDirectorGrant (A)20K$0
Jun 23, 2026Smith CynthiaDirectorGrant (A)10K$0
Jun 23, 2026Smith CynthiaDirectorGrant (A)20K$0
Jun 23, 2026THOMAS FRANK EDirectorGrant (A)10K$0
Jun 23, 2026THOMAS FRANK EDirectorGrant (A)20K$0
Jun 23, 2026VINK PATRICK V.J.J.DirectorGrant (A)10K$0
Jun 23, 2026VINK PATRICK V.J.J.DirectorGrant (A)20K$0
Jun 23, 2026Tregoning KathleenDirectorGrant (A)10K$0
Jun 23, 2026Tregoning KathleenDirectorGrant (A)20K$0

Institutional ownership over time

38 funds+1 since Q3 2024
02243Q3 2024Q1 2025Q3 2025Q1 2026
funds holding aggregate valuelatest $20.2M

Funds that own SPRO also own

CompanyCo-held byCombined value
AMAZON.COM INCAMZN12 funds$4.7B
MICROSOFT CORPMSFT12 funds$3.8B
ALPHABET INC-CL CGOOG12 funds$1.7B
COSTCO WHOLESALE CORPCOST12 funds$1.2B
VISA INC-CLASS A SHARESV12 funds$1.1B
ELI LILLY & COLLY12 funds$1.1B
ADVANCED MICRO DEVICESAMD12 funds$885.7M
RTX CORPRTX12 funds$875.1M
NETFLIX INCNFLX12 funds$453.3M
AUTOMATIC DATA PROCESSINGADP12 funds$248.1M
BRISTOL-MYERS SQUIBB COBMY12 funds$196.5M
GENERAL MOTORS COGM12 funds$166.7M

Ranked by how many of SPRO's institutional holders also hold each name, a cross-fund conviction signal. Via the MCP server (ticker.co_held).

Recent filings

15 shown

Browse more

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for SPRO. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes. Every panel above is one call to the Arkolith API & MCP server.