The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Jul 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | $14.50 | $109K |
| Jul 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 6K | $87.55 | $506K |
| Jul 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 2K | $88.37 | $152K |
| Jul 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | — | $0 |
| Jul 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | $27.46 | $229K |
| Jul 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 7K | $87.52 | $569K |
| Jul 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 2K | $88.34 | $162K |
| Jul 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | — | $0 |
| Jul 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 10K | $87.44 | $890K |
| Jul 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 4K | $88.12 | $373K |
| Jul 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 590 | $88.91 | $52K |
| Jun 25, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 15K | $14.50 | $218K |
| Jun 25, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 5K | $87.12 | $436K |
| Jun 25, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 10K | $87.14 | $871K |
| Jun 25, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 15K | — | $0 |
| Jun 23, 2026 | Fairmount Funds Management LLC | Director | Conversion(C) | 667K | — | — |
| Jun 23, 2026 | Fairmount Funds Management LLC | Director | Sell(S) | 4.7M | $85.31 | $399.7M |
| Jun 23, 2026 | Fairmount Funds Management LLC | Director | Conversion(C) | 17K | — | $0 |
| Jun 22, 2026 | Henderson Michael Thomas | Director | Sell(S) | 20K | $100.00 | $2.0M |
| Jun 3, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | $27.46 | $229K |
| Jun 3, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 8K | $75.00 | $625K |
| Jun 3, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | — | $0 |
| Jun 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | $14.50 | $109K |
| Jun 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 4K | $69.40 | $247K |
| Jun 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 8K | $70.50 | $575K |
| Jun 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 3K | $71.38 | $235K |
| Jun 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 2K | $69.75 | $126K |
| Jun 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 3K | $70.77 | $184K |
| Jun 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 3K | $72.06 | $223K |
| Jun 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | — | $0 |
| May 27, 2026 | Albers Jeffrey W. | Director | Grant(A) | 8K | — | $0 |
| May 27, 2026 | Fairmount Funds Management LLC | Director | Grant(A) | 8K | — | $0 |
| May 27, 2026 | McKenna Mark C. | Director | Grant(A) | 8K | — | $0 |
| May 27, 2026 | Henderson Michael Thomas | Director | Grant(A) | 8K | — | $0 |
| May 27, 2026 | Stelzer Laurie | Director | Grant(A) | 8K | — | $0 |
| May 27, 2026 | Milligan Sandra | Director | Grant(A) | 8K | — | $0 |
| May 8, 2026 | Henderson Michael Thomas | Director | Sell(S) | 2K | $72.57 | $174K |
| May 8, 2026 | Henderson Michael Thomas | Director | Sell(S) | 34K | $73.72 | $2.5M |
| May 8, 2026 | Henderson Michael Thomas | Director | Sell(S) | 25K | $74.76 | $1.9M |
| May 8, 2026 | Henderson Michael Thomas | Director | Sell(S) | 19K | $75.35 | $1.5M |
| May 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 13K | $14.50 | $181K |
| May 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 13K | $71.37 | $892K |
| May 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 13K | — | $0 |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 78K | $27.46 | $2.2M |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 21K | $69.53 | $1.5M |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 20K | $70.61 | $1.4M |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 9K | $71.56 | $628K |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 13K | $72.94 | $932K |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 10K | $73.74 | $764K |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 5K | $74.60 | $377K |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 400 | $75.37 | $30K |
| May 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 78K | — | $0 |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 5K | $69.54 | $369K |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 4K | $70.77 | $255K |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 1K | $71.76 | $72K |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 3K | $73.14 | $227K |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 2K | $74.23 | $126K |
| May 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 300 | $74.96 | $22K |
| Apr 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | $14.50 | $109K |
| Apr 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 6K | $49.21 | $305K |
| Apr 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 1K | $49.98 | $65K |
| Apr 1, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 8K | — | $0 |
| Apr 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 12K | $49.20 | $607K |
| Apr 1, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 3K | $49.92 | $133K |
| Apr 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | $21.66 | $172K |
| Apr 1, 2026 | Sloan Sheldon | Chief Medical Officer | Sell(S) | 8K | $50.00 | $398K |
| Apr 1, 2026 | Sloan Sheldon | Chief Medical Officer | Option exercise(M) | 8K | — | $0 |
| Mar 3, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 200 | $41.66 | $8K |
| Mar 3, 2026 | Burrows Scott L | Chief Financial Officer | Sell(S) | 2K | $40.56 | $93K |
| Mar 3, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 3K | $14.50 | $36K |
| Mar 3, 2026 | Burrows Scott L | Chief Financial Officer | Option exercise(M) | 3K | — | $0 |
| Mar 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 9K | $42.49 | $387K |
| Mar 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 6K | $41.73 | $246K |
| Feb 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 957 | $31.82 | $30K |
| Feb 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 14K | $32.87 | $462K |
| Jan 21, 2026 | Henderson Michael Thomas | Director | Other(J) | 63K | — | $0 |
| Jan 9, 2026 | King-Jones Heidy | See Remarks | Grant(A) | 140K | — | $0 |
| Jan 9, 2026 | Sloan Sheldon | Chief Medical Officer | Grant(A) | 140K | — | $0 |
| Jan 9, 2026 | Turtle Cameron | Chief Executive Officer, Director | Grant(A) | 528K | — | $0 |
| Jan 9, 2026 | Burrows Scott L | Chief Financial Officer | Grant(A) | 140K | — | $0 |
| Jan 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 13K | $30.47 | $387K |
| Jan 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 100 | $32.39 | $3K |
| Jan 2, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 2K | $31.79 | $70K |
| Dec 1, 2025 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 4K | $29.83 | $119K |
| Dec 1, 2025 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 11K | $28.73 | $316K |
| Nov 3, 2025 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 28K | $23.13 | $651K |
| Nov 3, 2025 | Turtle Cameron | Chief Executive Officer, Director | Sell(S) | 17K | $23.66 | $399K |
| Sep 2, 2025 | Burrows Scott L | Chief Financial Officer | Sell(S) | 18K | $16.26 | $300K |
| May 29, 2025 | Albers Jeffrey W. | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | Henderson Michael Thomas | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | McKenna Mark C. | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | Milligan Sandra | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | Stelzer Laurie | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | Fairmount Healthcare Fund II L.P. | Director | Grant(A) | 25K | — | $0 |
| May 29, 2025 | Fairmount Healthcare Fund II L.P. | Director | Grant(A) | 25K | — | $0 |
| Jan 15, 2025 | King-Jones Heidy | See Remarks | Grant(A) | 96K | — | $0 |
| Jan 15, 2025 | Turtle Cameron | Chief Executive Officer, Director | Grant(A) | 370K | — | $0 |
| Jan 15, 2025 | Sloan Sheldon | Chief Medical Officer | Grant(A) | 96K | — | $0 |
| Jan 15, 2025 | Burrows Scott L | Chief Financial Officer | Grant(A) | 96K | — | $0 |
| Jan 10, 2025 | Henderson Michael Thomas | Director | Other(J) | 105K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-01-04 → 2026-07-21. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).