210 tracked 13F filers disclose a position in SYRE as of the latest SEC 13F filings, a combined $4.4B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
| # | Fund | Position value | Shares | Last move | As of | History |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | $594.2M | 11.8M | ▲+1.2% Added · +142K sh | Q1 2026 | |
| 2 | BlackRock, Inc. | $278.5M | 5.5M | ▼~0% Reduced · −880 sh | Q1 2026 | |
| 3 | RTW INVESTMENTS, LP | $377.5M | 4.3M | ▲+1.9% Added · +80K sh | Q2 2026 | |
| 4 | PERCEPTIVE ADVISORS LLC | $190.8M | 3.8M | ▲+23% Added · +714K sh | Q1 2026 | |
| 5 | Venrock Adviser, LLC | $185.9M | 3.7M | —Held | Q1 2026 | |
| 6 | STATE STREET CORP | $271.4M | 3.1M | ▲+17% Added · +450K sh | Q2 2026 | |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | $154.2M | 3.1M | →First observed position No prior filed position | Q1 2026 | |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | $239.3M | 2.6M | ▲+49% Added · +841K sh | Q2 2026 | |
| 9 | Paradigm Biocapital Advisors LP | $98.7M | 2.0M | ▲+33% Added · +490K sh | Q1 2026 | |
| 10 | Commodore Capital LP | $96.5M | 1.9M | ▼−20% Reduced · −476K sh | Q1 2026 | |
| 11 | TCG Crossover Management, LLC | $95.9M | 1.9M | —Held | Q1 2026 | |
| 12 | TANG CAPITAL MANAGEMENT LLC | $95.4M | 1.9M | —Held | Q1 2026 | |
| 13 | Janus Henderson Group Ltd. | $83.6M | 1.7M | ▼−9.4% Reduced · −173K sh | Q1 2026 | |
| 14 | RA CAPITAL MANAGEMENT, L.P. | $81.8M | 1.6M | —Held | Q1 2026 | |
| 15 | PRICE T ROWE ASSOCIATES INC /MD/ | $80.6M | 1.6M | ▼−0.2% Reduced · −3K sh | Q1 2026 | |
| 16 | Remedium Capital Partners, LLC | $130.0M | 1.5M | ▲+0.5% Added · +8K sh | Q2 2026 | |
| 17 | Affinity Asset Advisors, LLC | $64.5M | 1.3M | ▼−11% Reduced · −153K sh | Q1 2026 | |
| 18 | BANK OF AMERICA CORP /DE/ | $61.9M | 1.2M | ▲+193% Added · +808K sh | Q1 2026 | |
| 19 | BAKER BROS. ADVISORS LP | $50.4M | 1.0M | —Held | Q1 2026 | |
| 20 | Polar Capital Holdings Plc | $87.7M | 988K | ▲+25% Added · +195K sh | Q2 2026 | |
| 21 | JPMORGAN CHASE & CO | $44.5M | 979K | ▲16× Added · +916K sh | Q1 2026 | |
| 22 | Siren, L.L.C. | $86.0M | 969K | ▲+18% Added · +150K sh | Q2 2026 | |
| 23 | FRANKLIN RESOURCES INC | $44.5M | 883K | ▼−20% Reduced · −226K sh | Q1 2026 | |
| 24 | BRAIDWELL LP | $78.1M | 879K | ▼−5.7% Reduced · −53K sh | Q2 2026 | |
| 25 | Caligan Partners LP | $44.3M | 878K | ▲New +878K sh | Q1 2026 |
Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
Last quarter, 18 funds opened a new position in SYRE and 18 added to an existing one, while 21 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).
| Company | Co-held by | Combined value |
|---|---|---|
| ELI LILLY & COLLY | 110 funds | $56.3B |
| AMAZON.COM INCAMZN | 108 funds | $133.4B |
| NVIDIA CORPNVDA | 106 funds | $280.2B |
| MICROSOFT CORPMSFT | 104 funds | $188.9B |
| MICRON TECHNOLOGY INCMU | 104 funds | $27.7B |
| INSMED INCINSM | 104 funds | $6.1B |
| META PLATFORMS INC-CLASS AMETA | 103 funds | $80.2B |
| REVOLUTION MEDICINES INCRVMD | 102 funds | $5.2B |
| CYTOKINETICS INCCYTK | 101 funds | $1.9B |
| BROADCOM INCAVGO | 100 funds | $113.1B |
| ALPHABET INC-CL AGOOGL | 100 funds | $108.6B |
| APPLE INCAAPL | 99 funds | $205.4B |
Ranked by how many of SYRE's institutional holders also hold each name, a cross-fund conviction signal.
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| Aug 7, 2026 | Albers Jeffrey W. | Director | Sell (S) | 5K | $522K |
| Aug 7, 2026 | Albers Jeffrey W. | Director | Sell (S) | 8K | $835K |
| Aug 7, 2026 | Albers Jeffrey W. | Director | Sell (S) | 10K | $1.0M |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell (S) | 800 | $75K |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell (S) | 7K | $681K |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell (S) | 6K | $541K |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell (S) | 1K | $135K |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer, Director | Sell (S) | 16 | $2K |
| Aug 3, 2026 | Burrows Scott L | Chief Financial Officer | Sell (S) | 5K | $486K |
| Aug 3, 2026 | Burrows Scott L | Chief Financial Officer | Sell (S) | 2K | $221K |
| Aug 3, 2026 | Burrows Scott L | Chief Financial Officer | Sell (S) | 100 | $10K |
| Jul 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell (S) | 6K | $506K |
Connected entities for SYRE
This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.
curl -H "Authorization: Bearer YOUR_API_KEY" \ "https://arkolith.com/api/v1/stocks/SYRE/capital-change-brief"
Use Arkolith's capital_change_brief for SYRE. Tell me what changed, whether insider activity corroborates it, and cite the SEC evidence.
13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for SYRE. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.