The public view is the crawlable proof. The same sourced dataset is available through REST and MCP for agents, research scripts, and back-office tools.
| Date | Insider | Role | Action | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Nov 25, 2022 | Bonita David P | Director, 10% Owner | Sell(S) | 3.6M | $0.22 | $798K |
| Nov 25, 2022 | Orbimed Advisors LLC | Director, 10% Owner | Sell(S) | 3.6M | $0.22 | $798K |
| Nov 23, 2022 | Bonita David P | Director, 10% Owner | Sell(S) | 5.6M | $0.21 | $1.2M |
| Nov 23, 2022 | Orbimed Advisors LLC | Director, 10% Owner | Sell(S) | 5.6M | $0.21 | $1.2M |
| Nov 23, 2022 | Alpern Robert J | Director | Sell(S) | 132K | $0.21 | $28K |
| Nov 22, 2022 | Bonita David P | Director, 10% Owner | Sell(S) | 1.0M | $0.22 | $228K |
| Nov 22, 2022 | Orbimed Advisors LLC | Director, 10% Owner | Sell(S) | 1.0M | $0.22 | $228K |
| Nov 21, 2022 | Alpern Robert J | Director | Sell(S) | 28K | $0.23 | $6K |
| Oct 26, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Sell(S) | 2.4M | $0.46 | $1.1M |
| Oct 25, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Sell(S) | 2.0M | $0.57 | $1.1M |
| Oct 24, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Sell(S) | 2.1M | $0.61 | $1.3M |
| Oct 19, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 241K | $10.29 | $2.5M |
| Oct 19, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 70K | $11.25 | $789K |
| Oct 18, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 40K | $11.98 | $484K |
| Oct 17, 2022 | Shah Nimish P | 10% Owner | Buy(P) | 170K | $11.67 | $2.0M |
| Oct 13, 2022 | Shah Nimish P | 10% Owner | Buy(P) | 5K | $11.98 | $56K |
| Oct 13, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 24K | $11.99 | $283K |
| Oct 13, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 6K | $11.99 | $68K |
| Oct 12, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 171K | $12.53 | $2.1M |
| Oct 12, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 41K | $12.53 | $517K |
| Oct 11, 2022 | Shah Nimish P | 10% Owner | Buy(P) | 25K | $11.85 | $296K |
| Oct 11, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 95K | $12.01 | $1.1M |
| Oct 11, 2022 | Sibling Capital Fund II-C L.P. | 10% Owner | Sell(S) | 23K | $12.01 | $276K |
| Oct 10, 2022 | Shah Nimish P | 10% Owner | Buy(P) | 80K | $11.89 | $955K |
| Oct 7, 2022 | Shah Nimish P | 10% Owner | Buy(P) | 29K | $12.00 | $347K |
| Oct 4, 2022 | VHCP Co-Investment Holdings III, LLC | 10% Owner | Buy(P) | 223K | $11.81 | $2.6M |
| Oct 3, 2022 | Venrock Healthcare Capital Partners EG, L.P. | 10% Owner | Buy(P) | 269K | $11.27 | $3.0M |
| Oct 3, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 23K | $11.16 | $254K |
| Oct 3, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 36K | $11.16 | $400K |
| Oct 3, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 10K | $11.16 | $115K |
| Sep 30, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 33K | $10.67 | $352K |
| Sep 30, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 52K | $10.67 | $555K |
| Sep 30, 2022 | Sibling Capital Fund II-A L.P. | 10% Owner | Sell(S) | 15K | $10.67 | $160K |
| Sep 29, 2022 | Venrock Healthcare Capital Partners EG, L.P. | 10% Owner | Buy(P) | 168K | $9.92 | $1.7M |
| Sep 28, 2022 | VHCP Co-Investment Holdings III, LLC | 10% Owner | Buy(P) | 77K | $9.92 | $760K |
| Sep 27, 2022 | VHCP Co-Investment Holdings III, LLC | 10% Owner | Buy(P) | 115K | $9.38 | $1.1M |
| Sep 26, 2022 | VHCP Co-Investment Holdings III, LLC | 10% Owner | Buy(P) | 396K | $8.56 | $3.4M |
| Sep 7, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 473K | $11.40 | $5.4M |
| Sep 6, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 150K | $11.43 | $1.7M |
| Sep 2, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 63K | $12.76 | $804K |
| Aug 30, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 50K | $12.20 | $610K |
| Aug 16, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 11K | $13.59 | $147K |
| Aug 16, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 5K | $13.59 | $67K |
| Aug 16, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 17K | $13.59 | $232K |
| Aug 15, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 6K | $13.42 | $75K |
| Aug 15, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 12K | $13.42 | $165K |
| Aug 15, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 19K | $13.42 | $261K |
| Aug 12, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 32K | $13.50 | $435K |
| Aug 12, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 112K | $13.50 | $1.5M |
| Aug 12, 2022 | Sibling Capital Fund II-B L.P. | 10% Owner | Sell(S) | 71K | $13.50 | $957K |
| Aug 5, 2022 | Yoshiyama Annie | Senior VP, Finance and CAO | Grant(A) | 14K | — | $0 |
| Jul 29, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 19K | $9.21 | $174K |
| Jul 25, 2022 | VHCP Co-Investment Holdings II, LLC | 10% Owner | Buy(P) | 29K | $8.95 | $261K |
| Jul 22, 2022 | VHCP Co-Investment Holdings II, LLC | 10% Owner | Buy(P) | 15K | $9.21 | $138K |
| Jul 21, 2022 | VHCP Co-Investment Holdings II, LLC | 10% Owner | Buy(P) | 30K | $9.59 | $288K |
| Jul 20, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 25K | $9.54 | $239K |
| Jul 19, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 25K | $9.47 | $237K |
| Jul 18, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 100K | $9.02 | $902K |
| Jul 14, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 37K | $9.85 | $362K |
| Jul 13, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 33K | $9.98 | $328K |
| Jul 12, 2022 | Koh Bong Y | 10% Owner | Buy(P) | 25K | $9.81 | $245K |
| Jul 5, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 33K | $9.53 | $310K |
| Jul 1, 2022 | Venrock Healthcare Capital Partners II, L.P. | 10% Owner | Buy(P) | 56K | $9.65 | $538K |
| Jun 30, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 12K | $9.66 | $116K |
| Jun 29, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 17K | $9.93 | $164K |
| Jun 28, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 34K | $9.71 | $334K |
| Jun 24, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 149K | $9.68 | $1.4M |
| Jun 23, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 200K | $10.50 | $2.1M |
| Jun 22, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 143K | $10.90 | $1.6M |
| Jun 16, 2022 | VHCP Management EG, LLC | 10% Owner | Buy(P) | 6K | $9.69 | $58K |
| Jun 15, 2022 | Falberg Kathryn E | Director | Grant(A) | 27K | — | $0 |
| Jun 15, 2022 | Veitinger Klaus R DR | Director | Grant(A) | 27K | — | $0 |
| Jun 15, 2022 | Bonita David P | Director, 10% Owner | Grant(A) | 27K | — | $0 |
| Jun 15, 2022 | Hirsch David | Director | Grant(A) | 27K | — | $0 |
| Jun 15, 2022 | Alpern Robert J | Director | Grant(A) | 27K | — | $0 |
| Jun 15, 2022 | Coufal Sandra I | Director, 10% Owner | Grant(A) | 27K | — | $0 |
| Jun 14, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 10K | $8.72 | $87K |
| Jun 13, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 50K | $8.14 | $407K |
| Jun 10, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 58K | $8.91 | $517K |
| Jun 9, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 109K | $8.97 | $979K |
| Jun 8, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 111K | $9.51 | $1.1M |
| Jun 7, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 368K | $9.89 | $3.6M |
| Jun 6, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 92K | $9.35 | $856K |
| Jun 3, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 38K | $9.33 | $351K |
| Jun 2, 2022 | VHCP Management II, LLC | 10% Owner | Buy(P) | 62K | $8.78 | $542K |
| Apr 28, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 4K | $10.61 | $41K |
| Apr 28, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 2K | $10.61 | $19K |
| Apr 28, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 6K | $10.61 | $65K |
| Apr 27, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 5K | $10.97 | $55K |
| Apr 27, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 11K | $10.97 | $122K |
| Apr 27, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 17K | $10.97 | $191K |
| Apr 26, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 109 | $11.90 | $1K |
| Apr 26, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 377 | $11.90 | $4K |
| Apr 26, 2022 | Sibling Capital Ventures III LLC | 10% Owner | Sell(S) | 240 | $11.90 | $3K |
| Mar 22, 2022 | Coufal Sandra I | Director, 10% Owner | Other(J) | 1.8M | — | — |
| Mar 22, 2022 | Coufal Sandra I | Director, 10% Owner | Other(J) | 2.8M | — | — |
| Mar 22, 2022 | Coufal Sandra I | Director, 10% Owner | Other(J) | 777K | — | — |
| Mar 22, 2022 | Coufal Sandra I | Director, 10% Owner | Other(J) | 599K | — | — |
| Mar 22, 2022 | Coufal Sandra I | Director, 10% Owner | Other(J) | 463K | — | — |
| Feb 28, 2022 | Klaerner Gerrit | President and CEO, Director | Grant(A) | 511K | — | $0 |
Insider transactions sourced from SEC EDGAR Form 4 filings, normalized within minutes of acceptance. "Buy"/"Sell" mark open-market transactions (codes P/S), the tradeable signal. Awards, option exercises and tax-withholding are shown with their raw code. All data is public domain.
Coverage: Form 4 filings indexed 2021-03-29 → 2026-07-11. Earlier history is backfilling; this window widens as it deepens.
Programmatic access via the Arkolith API & MCP server (insider.transactions, insider.company).