IONS

Ionis Pharmaceuticals Inc$54.65 0.15%
Health CareUSCUSIP 462222100· EOD Jul 16, 2026◍ Confluence graph
Tracked 13F Holders
359
+9 QoQ
13F Value (tracked)
$9.7B
Insider Net · 180d
-$90.8M
0↑ 16↓
Recent Filings
15
Smart-money sentimentMixed
BearishBullish
13F funds (latest Q)34 adding · 20 trimming
Insider net (180d)-$90.8M

Price & smart-money activity

$54.65 0.15%5Y +53.7%
$21.32$38.82$56.33$73.83$91.332021202220232024202520263953523934553505335160635020506533426434452556349636286367772554256762367633837017811577113951189395
Hover for who · click for detailEnd-of-day closing prices52w $40.69 – $86.50
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Ask your agent what changed in IONS

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/IONS/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for IONS.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

Top institutional holders

359 tracked 13F filers
3 source-reported value rows are withheld because the reported units do not agree with same-security peers. Share counts remain visible and unchanged.
#FundPosition valueSharesLast moveAs ofHistory
1FMR LLC
$1.8B
24.6M
+2.0%
Added · +485K sh
Q1 2026
2BlackRock, Inc.
$784.1M
10.4M
−1.9%
Reduced · −205K sh
Q1 2026
3VANGUARD PORTFOLIO MANAGEMENT LLC
$586.4M
7.8M
New
+7.8M sh
Q1 2026
4VANGUARD CAPITAL MANAGEMENT LLC
$534.5M
7.1M
New
+7.1M sh
Q1 2026
5T. Rowe Price Investment Management, Inc.
Withheld
6.2M
−32%
Reduced · −2.9M sh
Q1 2026
6TWO SIGMA INVESTMENTS, LP
$439.8M
5.9M
+120%
Added · +3.2M sh
Q1 2026
7STATE STREET CORP
$300.0M
4.0M
+0.5%
Added · +21K sh
Q1 2026
8GEODE CAPITAL MANAGEMENT, LLC
$305.2M
4.0M
+27%
Added · +835K sh
Q1 2026
9ROYAL BANK OF CANADA
$285.5M
3.8M
+240%
Added · +2.7M sh
Q1 2026
10PRICE T ROWE ASSOCIATES INC /MD/
$227.2M
3.0M
+1.3%
Added · +37K sh
Q1 2026
11JPMORGAN CHASE & CO
$171.4M
2.4M
+2.5%
Added · +59K sh
Q1 2026
12Artisan Partners Limited Partnership
$154.6M
2.1M
+74%
Added · +877K sh
Q1 2026
13BAKER BROS. ADVISORS LP
$153.8M
2.0M
+14%
Added · +256K sh
Q1 2026
14DEERFIELD MANAGEMENT COMPANY, L.P.
$148.7M
2.0M
Held
Q1 2026
15Deep Track Capital, LP
$146.4M
1.9M
+15%
Added · +250K sh
Q1 2026
16Bellevue Group AG
$136.6M
1.8M
−62%
Reduced · −3.0M sh
Q1 2026
17GOLDMAN SACHS GROUP INC
$127.6M
1.7M
+99%
Added · +844K sh
Q1 2026
18AMERICAN CENTURY COMPANIES INC
$124.9M
1.7M
+2.9%
Added · +47K sh
Q1 2026
19CHARLES SCHWAB INVESTMENT MANAGEMENT INC
$118.9M
1.6M
+2.7%
Added · +41K sh
Q1 2026
20FRANKLIN RESOURCES INC
$118.3M
1.6M
+19%
Added · +254K sh
Q1 2026
21UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME
$110.8M
1.5M
+6.3%
Added · +87K sh
Q1 2026
22Pictet Asset Management Holding SA
$107.1M
1.4M
+1.2%
Added · +17K sh
Q1 2026
23SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC
$105.4M
1.4M
−4.0%
Reduced · −59K sh
Q1 2026
24MILLENNIUM MANAGEMENT LLC
$79.0M
1.1M
11×
Added · +958K sh
Q1 2026
25MORGAN STANLEY
$77.1M
1.0M
+0.6%
Added · +7K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Fund activity: latest quarter

Opened (NEW)
5
funds
Added
29
funds
Reduced
20
funds
Exited
0
funds

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$90.8M
16 insiders
Net
-$90.8M
76 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jul 15, 2026Reikes Peter NDirectorGrant (A)3K$0
Jul 15, 2026BERTHELSEN SPENCER RDirectorOption exercise (M)5K$0
Jul 15, 2026BERTHELSEN SPENCER RDirectorOption exercise (M)5K$0
Jul 15, 2026HERMAN JOAN EDirectorOption exercise (M)5K$0
Jul 15, 2026HERMAN JOAN EDirectorOption exercise (M)5K$0
Jul 15, 2026HANTSON LUDWIGDirectorGrant (A)3K$0
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerOther (J)15K$0
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSell (S)15K$1.3M
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerOther (J)15K$0
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSell (S)6K$463K
Jul 7, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSell (S)362$31K
Jul 7, 2026Diaz Allene M.DirectorOption exercise (M)10K$0

Institutional ownership over time

354 funds+119 since Q3 2024
0177354Q3 2024Q1 2025Q3 2025Q1 2026
funds holding aggregate valuelatest $9.7B · 3 values withheld

Funds that own IONS also own

CompanyCo-held byCombined value
MICROSOFT CORPMSFT173 funds$69.1B
NVIDIA CORPNVDA171 funds$101.2B
META PLATFORMS INC-CLASS AMETA170 funds$30.8B
AMAZON.COM INCAMZN169 funds$51.9B
BROADCOM INCAVGO169 funds$37.9B
ELI LILLY & COLLY169 funds$17.9B
TESLA INCTSLA168 funds$21.8B
INTUITIVE SURGICAL INCISRG167 funds$5.6B
BOSTON SCIENTIFIC CORPBSX167 funds$4.2B
ALPHABET INC-CL AGOOGL166 funds$46.2B
APPLE INCAAPL165 funds$81.0B
DANAHER CORPDHR165 funds$3.6B

Ranked by how many of IONS's institutional holders also hold each name, a cross-fund conviction signal. Via the MCP server (ticker.co_held).

Recent filings

15 shown

Browse more

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for IONS. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes. Every panel above is one call to the Arkolith API & MCP server.