IONS

Ionis Pharmaceuticals Inc
Health CareUSCUSIP 462222100◍ Confluence graph
Tracked 13F Holders
450
-183 QoQ
13F Value (tracked)
$10.0B
Insider Net · 180d
-$61.5M
1↑ 16↓
Recent Filings
15
Smart-money sentimentMixed
BearishBullish
13F funds (latest Q)37 adding · 18 trimming
Insider net (180d)-$61.5M

Who owns IONS?

450 tracked 13F filers

450 tracked 13F filers disclose a position in IONS as of the latest SEC 13F filings, a combined $10.0B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

All quarters use one ordinary-share-equivalent series. Historical ADS are converted at 2 ADS = 1 ordinary share. Expand a row for the exact calculation; the residual is not classified as a trade.
3 source-reported value rows are withheld because the reported units do not agree with same-security peers. Share counts remain visible and unchanged.
#FundPosition valueSharesLast moveAs ofHistory
1FMR LLC
$1.8B
24.6M
+2.0%
Added · +485K sh
Q1 2026
2BlackRock, Inc.
$784.1M
10.4M
−1.9%
Reduced · −205K sh
Q1 2026
3VANGUARD PORTFOLIO MANAGEMENT LLC
$586.4M
7.8M
First observed position
No prior filed position
Q1 2026
4VANGUARD CAPITAL MANAGEMENT LLC
$534.5M
7.1M
First observed position
No prior filed position
Q1 2026
5T. Rowe Price Investment Management, Inc.
Withheld
6.2M
−32%
Reduced · −2.9M sh
Q1 2026
6TWO SIGMA INVESTMENTS, LP
$439.8M
5.9M
+120%
Added · +3.2M sh
Q1 2026
7STATE STREET CORP
$343.7M
4.3M
+8.5%
Added · +339K sh
Q2 2026
8ROYAL BANK OF CANADA
$285.5M
3.8M
+240%
Added · +2.7M sh
Q1 2026
9GEODE CAPITAL MANAGEMENT, LLC
$294.8M
3.6M
−10%
Reduced · −400K sh
Q2 2026
10PRICE T ROWE ASSOCIATES INC /MD/
$227.2M
3.0M
+1.3%
Added · +37K sh
Q1 2026
11JPMORGAN CHASE & CO
$171.4M
2.4M
+2.5%
Added · +59K sh
Q1 2026
12Tweedy, Browne Co LLC
$180.8M
2.3M
+0.2%
Added · +5K sh
Q2 2026
13Artisan Partners Limited Partnership
$154.6M
2.1M
+74%
Added · +877K sh
Q1 2026
14BAKER BROS. ADVISORS LP
$153.8M
2.0M
+14%
Added · +256K sh
Q1 2026
15DEERFIELD MANAGEMENT COMPANY, L.P.
$148.7M
2.0M
Held
Q1 2026
16Deep Track Capital, LP
$146.4M
1.9M
+15%
Added · +250K sh
Q1 2026
17GOLDMAN SACHS GROUP INC
$127.6M
1.7M
+99%
Added · +844K sh
Q1 2026
18AMERICAN CENTURY COMPANIES INC
$124.9M
1.7M
+2.9%
Added · +47K sh
Q1 2026
19CHARLES SCHWAB INVESTMENT MANAGEMENT INC
$118.9M
1.6M
+2.7%
Added · +41K sh
Q1 2026
20FRANKLIN RESOURCES INC
$118.3M
1.6M
+19%
Added · +254K sh
Q1 2026
21UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME
$110.8M
1.5M
+6.3%
Added · +87K sh
Q1 2026
22Polar Capital Holdings Plc
$115.3M
1.5M
+75%
Added · +625K sh
Q2 2026
23Pictet Asset Management Holding SA
$107.1M
1.4M
+1.2%
Added · +17K sh
Q1 2026
24MILLENNIUM MANAGEMENT LLC
$79.0M
1.1M
11×
Added · +958K sh
Q1 2026
25MORGAN STANLEY
$77.1M
1.0M
+0.6%
Added · +7K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Is IONS being bought or sold by institutions?

Last quarter, 4 funds opened a new position in IONS and 33 added to an existing one, while 18 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).

Opened (NEW)
4
funds
Added
33
funds
Reduced
18
funds
Exited
0
funds

Funds that own IONS also own

CompanyCo-held byCombined value
NVIDIA CORPNVDA268 funds$411.0B
ELI LILLY & COLLY266 funds$81.2B
MICROSOFT CORPMSFT265 funds$286.7B
AMAZON.COM INCAMZN264 funds$211.1B
META PLATFORMS INC-CLASS AMETA261 funds$115.9B
BROADCOM INCAVGO258 funds$162.6B
ALPHABET INC-CL AGOOGL256 funds$180.9B
APPLE INCAAPL254 funds$315.8B
JOHNSON & JOHNSONJNJ250 funds$50.9B
INTUITIVE SURGICAL INCISRG249 funds$28.2B
TESLA INCTSLA248 funds$72.3B
MICRON TECHNOLOGY INCMU248 funds$46.4B

Ranked by how many of IONS's institutional holders also hold each name, a cross-fund conviction signal.

Insider activity (Form 4)

Full insider page →
Buys · 180d
$1.1M
1 insiders
Sells · 180d
$62.5M
16 insiders
Net
-$61.5M
46 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jul 31, 2026Hayden Michael RDirectorBuy (P)5K$258K
Jul 30, 2026Hayden Michael RDirectorBuy (P)15K$801K
Jul 7, 2026Diaz Allene M.DirectorSell (S)10K$864K
Jul 7, 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSell (S)362$31K
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSell (S)6K$463K
Jul 7, 2026BENNETT C FRANKEVP, Chief Scientific OfficerSell (S)15K$1.3M
Jul 1, 2026KLEIN JOSEPH IIIDirectorSell (S)99$8K
Jul 1, 2026KLEIN JOSEPH IIIDirectorSell (S)11K$903K
Jun 26, 2026Monia Brett PChief Executive Officer, DirectorSell (S)50K$4.0M
Jun 26, 2026Baroldi JosephEVP, Chief Business OfficerSell (S)6K$452K
Jun 26, 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSell (S)26K$2.1M
Jun 26, 2026O'NEIL PATRICK R.EVP CLO & General CounselSell (S)3K$246K

Institutional ownership over time

250 funds-10 since Q3 2024
0217433Q3 2024Q1 2025Q3 2025Q1 2026Q2 2026
funds holding aggregate valuelatest $1.9B · 1 values withheld

Share classes

Class13F holdersValue held
IONSthis pagecs450 funds$10.0B
IONS 1.75 06/15/28NOTE 1.750% 6/146 funds$837.8M

Same issuer, multiple share classes. The consensus leaderboards count this company once across all classes; this is the per-class detail.

Recent filings

15 shown

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Connected entities for IONS

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Ask your agent what changed in IONS

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

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  "https://arkolith.com/api/v1/stocks/IONS/capital-change-brief"
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Use Arkolith's capital_change_brief for IONS.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for IONS. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.