Arkolith/Funds/Rock Springs Capital Management LP

Rock Springs Capital Management LP

CIK 1595725
Holdings as of Mar 31, 2026·disclosed May 15, 2026·~45-day 13F lag·13F-HR
Active Filer

Rock Springs Capital Management LP holds a diversified book of 100 stocks worth $1.7B as of Q1 2026 (disclosed May 15, 2026, a ~45-day 13F lag). This quarter they opened Minimed Group Inc and trimmed Revolution Medicines Inc. Their largest long position is Revolution Medicines Inc at 7% of the equity book.

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holdings, largest changes, and filing provenance.
Opened
11
new positions
Added to
38
existing
Trimmed
24
reduced
Sold out
8
exited

Concentration

Top-heavy: diversified book

Top 5 holdings
26%
Top 10 holdings
41%
Top 20 holdings
60%

Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.

Direct sector allocation

95% mapped to company sectors

Health Care
93%
ETF / fund or unclassified
5%
Industrials
1%
Information Technology
0%
Consumer Staples
0%

Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.

Biggest moves: latest quarter

Estimated $ traded · quarter-end prices, no cost basis

Bought
Trimmed / exited

Holdings: largest first

Bars show each stock's share of the portfolio. Click a row for its position history.

100 positions
#SecurityValueShares% PortLast moveHistory
1Revolution Medicines Inc
COM
$117.6M1.21M
6.9%
−9.4%
Reduced · −126K sh
2Eli Lilly & Co
COM
$90.8M98.7K
5.4%
−6.3%
Reduced · −7K sh
3Madrigal Pharmaceuticals Inc
COM
$89.5M171.0K
5.3%
+22%
Added · +31K sh
4Mirum Pharmaceuticals Inc
COM
$74.9M811.3K
4.4%
+6.4%
Added · +49K sh
5Argenx SE
SPONSORED ADR
$71.9M98.5K
4.2%
−4.6%
Reduced · −5K sh
6Rhythm Pharmaceuticals Inc
COM
$60.0M689.7K
3.5%
−0.8%
Reduced · −5K sh
7Insmed Inc
COM PAR $.01
$51.4M314.3K
3.0%
−1.6%
Reduced · −5K sh
8Ascendis Pharma A/s
SPONSORED ADR
$44.4M194.0K
2.6%
−4.7%
Reduced · −10K sh
9Xenon Pharmaceuticals Inc
COM
$44.4M763.0K
2.6%
−3.1%
Reduced · −25K sh
10Travere Therapeutics Inc
COM
$43.9M1.48M
2.6%
−33%
Reduced · −732K sh
11Kymera Therapeutics Inc
COM
$41.4M496.9K
2.4%
Held
12Penumbra Inc
COM
$39.6M120.5K
2.3%
Held
13Intuitive Surgical Inc
COM NEW
$37.8M82.0K
2.2%
Held
14Scholar Rock Hldg Corp
COM
$36.4M739.8K
2.1%
+0.9%
Added · +6K sh
15Enliven Therapeutics Inc
COM
$32.4M826.5K
1.9%
+3.5%
Added · +28K sh
16Boston Scientific Corp
COM
$32.3M515.3K
1.9%
+29%
Added · +116K sh
17Irhythm Holdings Inc
COM
$30.9M261.8K
1.8%
+11%
Added · +27K sh
18Structure Therapeutics Inc
SPONSORED ADS
$30.9M640.2K
1.8%
−14%
Reduced · −108K sh
19Agios Pharmaceuticals Inc
COM
$27.0M799.2K
1.6%
Held
20Ultragenyx Pharmaceutical In
COM
$25.5M1.22M
1.5%
−3.8%
Reduced · −48K sh
21Alnylam Pharmaceuticals Inc
COM
$24.5M74.0K
1.4%
+3.9%
Added · +3K sh
22Cogent Biosciences Inc
COM
$24.0M624.2K
1.4%
−26%
Reduced · −225K sh
23Tenet Healthcare Corp
COM NEW
$23.6M125.0K
1.4%
Held
24Dexcom Inc
COM
$22.3M355.6K
1.3%
+2.4%
Added · +8K sh
25Celldex Therapeutics Inc New
COM NEW
$20.6M650.3K
1.2%
−6.1%
Reduced · −42K sh
26Vera Therapeutics Inc
CL A
$20.3M503.6K
1.2%
−11%
Reduced · −65K sh
27Neurocrine Biosciences Inc
COM
$19.8M150.4K
1.2%
+20%
Added · +25K sh
28Arcellx Inc
COMMON STOCK
$19.5M169.9K
1.1%
Held
29Newamsterdam Pharma Company
ORDINARY SHARES
$18.8M588.8K
1.1%
+5.7%
Added · +32K sh
30Pharvaris N V
COM
$18.2M645.5K
1.1%
+3.5%
Added · +22K sh
31Erasca Inc
COM
$17.9M1.10M
1.1%
+16%
Added · +152K sh
32Dyne Therapeutics Inc
COM
$17.6M972.2K
1.0%
+6.5%
Added · +59K sh
33Compass Therapeutics Inc
COM
$17.5M3.31M
1.0%
−16%
Reduced · −622K sh
34Aclaris Therapeutics Inc
COM
$16.8M4.47M
1.0%
+0.4%
Added · +19K sh
35Tarsus Pharmaceuticals Inc
COM
$15.8M225.2K
0.9%
−14%
Reduced · −35K sh
36Minimed Group Inc
COM
$15.7M1.05M
0.9%
New
New position
37Zai Lab Ltd
ADR
$15.3M814.7K
0.9%
+0.4%
Added · +3K sh
38Unitedhealth Group Inc
COM
$14.3M53.0K
0.8%
+30%
Added · +12K sh
39Centessa Pharmaceuticals PLC
SPONSORED ADS
$14.0M351.8K
0.8%
+8.6%
Added · +28K sh
40Heartflow Inc
COM
$13.9M572.5K
0.8%
+106%
Added · +295K sh
41Ardelyx Inc
COM
$13.8M2.30M
0.8%
Held
42Summit Therapeutics Inc
COM
$13.5M710.0K
0.8%
Held
43Azenta Inc
COM
$12.0M569.1K
0.7%
Held
44Mineralys Therapeutics Inc
COM
$11.9M439.8K
0.7%
+2.8%
Added · +12K sh
45Danaher Corp Del
COM
$11.7M61.5K
0.7%
Held
46PTC Therapeutics Inc
COM
$11.0M161.8K
0.6%
+161%
Added · +100K sh
47Caris Life Sciences Inc
COM
$10.1M563.0K
0.6%
−18%
Reduced · −125K sh
48Zenas Biopharma Inc
COM
$9.8M502.1K
0.6%
Held
49Bicara Therapeutics Inc
COM
$9.7M489.1K
0.6%
+14%
Added · +60K sh
50Bridgebio Pharma Inc
COM
$9.5M128.3K
0.6%
+24%
Added · +25K sh
Showing 50 of 100 positions

Filing history

As-of date vs the date the SEC received each filing

QuarterAs ofFiledPositionsValueForm
Q1 2026Mar 31, 2026May 15, 2026100$1.7B13F-HR
Q4 2025Dec 31, 2025Feb 17, 202699$2.0B13F-HR
Q3 2025Sep 30, 2025Nov 14, 202593$1.7B13F-HR
Q2 2025Jun 30, 2025Aug 14, 202593$1.6B13F-HR
Q1 2025Mar 31, 2025May 15, 202596$1.7B13F-HR
Q4 2024Dec 31, 2024Feb 14, 2025107$2.6B13F-HR
Q3 2024Sep 30, 2024Nov 14, 2024109$3.1B13F-HR
Q2 2024Jun 30, 2024Aug 14, 2024112$3.3B13F-HR
Q1 2024Mar 31, 2024May 15, 2024114$3.9B13F-HR
Q4 2023Dec 31, 2023Feb 14, 2024104$4.1B13F-HR
Q3 2023Sep 30, 2023Nov 14, 2023120$3.7B13F-HR
Q2 2023Jun 30, 2023Aug 14, 2023123$4.2B13F-HR
Q1 2023Mar 31, 2023May 15, 2023121$4.2B13F-HR
Q4 2022Dec 31, 2022Feb 14, 2023120$4.2B13F-HR
Q3 2022Sep 30, 2022Nov 14, 2022128$3.9B13F-HR
Q2 2022Jun 30, 2022Aug 15, 2022131$3.4B13F-HR
Q1 2022Mar 31, 2022May 16, 2022135$4.0B13F-HR
Q4 2021Dec 31, 2021Feb 14, 2022136$4.3B13F-HR
Q3 2021Sep 30, 2021Nov 15, 2021153$4.8B13F-HR
Q2 2021Jun 30, 2021Aug 16, 2021156$5.1B13F-HR
Q1 2021Mar 31, 2021May 17, 2021151$4.6B13F-HR
Q4 2020Dec 31, 2020Feb 16, 2021155$4.7B13F-HR
Q3 2020Sep 30, 2020Nov 16, 2020148$3.9B13F-HR
Q2 2020Jun 30, 2020Aug 14, 2020143$3.6B13F-HR

Data source

Holdings from SEC EDGAR 13F-HR filings, updated quarterly ~45 days after quarter-end. Public domain. The book and weighting are long equity only; disclosed put/call options are listed separately and excluded from those totals. Price-derived performance is withheld until the price-source policy and freshness gate are green.