276 tracked 13F filers disclose a position in XENE as of the latest SEC 13F filings, a combined $5.0B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
| # | Fund | Position value | Shares | Last move | As of | History |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | $629.1M | 10.8M | ▲+21% Added · +1.9M sh | Q1 2026 | |
| 2 | Avoro Capital Advisors LLC | $348.7M | 5.8M | —Held | Q2 2026 | |
| 3 | BlackRock, Inc. | $328.0M | 5.6M | ▲+11% Added · +540K sh | Q1 2026 | |
| 4 | Polar Capital Holdings Plc | $275.9M | 4.6M | ▲+3.8% Added · +165K sh | Q2 2026 | |
| 5 | JANUS HENDERSON GROUP PLC | $242.9M | 4.2M | ▲+2.3% Added · +92K sh | Q1 2026 | |
| 6 | CITADEL ADVISORS LLC | $154.3M | 2.7M | ▲+101% Added · +1.3M sh | Q1 2026 | |
| 7 | STATE STREET CORP | $118.9M | 2.0M | ▲+14% Added · +249K sh | Q2 2026 | |
| 8 | JPMORGAN CHASE & CO | $106.9M | 1.9M | ▲+29% Added · +430K sh | Q1 2026 | |
| 9 | Affinity Asset Advisors, LLC | $97.4M | 1.7M | ▲+34% Added · +425K sh | Q1 2026 | |
| 10 | DEERFIELD MANAGEMENT COMPANY, L.P. | $94.0M | 1.6M | ▲+198% Added · +1.1M sh | Q1 2026 | |
| 11 | Holocene Advisors, LP | $88.3M | 1.5M | ▲+18% Added · +237K sh | Q1 2026 | |
| 12 | WESTFIELD CAPITAL MANAGEMENT CO LP | $91.0M | 1.5M | ▲+7.5% Added · +106K sh | Q2 2026 | |
| 13 | ALLIANCEBERNSTEIN L.P. | $62.9M | 1.4M | ▼−12% Reduced · −191K sh | Q1 2026 | |
| 14 | Caligan Partners LP | $81.0M | 1.4M | ▲+153% Added · +843K sh | Q1 2026 | |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | $82.7M | 1.4M | ▲+25% Added · +277K sh | Q2 2026 | |
| 16 | BNP Paribas Asset Management Holding S.A. | $78.0M | 1.3M | ▲+27% Added · +282K sh | Q1 2026 | |
| 17 | PRICE T ROWE ASSOCIATES INC /MD/ | $77.3M | 1.3M | ▲+54% Added · +467K sh | Q1 2026 | |
| 18 | JENNISON ASSOCIATES LLC | $76.7M | 1.3M | ▲+2.1% Added · +27K sh | Q1 2026 | |
| 19 | Siren, L.L.C. | $79.6M | 1.3M | —Held | Q2 2026 | |
| 20 | Alyeska Investment Group, L.P. | $75.6M | 1.3M | ▲New +1.3M sh | Q1 2026 | |
| 21 | FRANKLIN RESOURCES INC | $74.5M | 1.3M | ▲+69% Added · +523K sh | Q1 2026 | |
| 22 | BRAIDWELL LP | $68.3M | 1.1M | ▼−15% Reduced · −207K sh | Q2 2026 | |
| 23 | ORBIMED ADVISORS LLC | $61.6M | 1.1M | ▲+137% Added · +613K sh | Q1 2026 | |
| 24 | FEDERATED HERMES, INC. | $56.5M | 972K | ▲+45% Added · +300K sh | Q1 2026 | |
| 25 | T. Rowe Price Investment Management, Inc. | Withheld | 952K | ▲+74% Added · +404K sh | Q1 2026 |
Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
Last quarter, 9 funds opened a new position in XENE and 35 added to an existing one, while 22 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).
| Company | Co-held by | Combined value |
|---|---|---|
| AMAZON.COM INCAMZN | 147 funds | $186.5B |
| ELI LILLY & COLLY | 145 funds | $75.5B |
| MICROSOFT CORPMSFT | 142 funds | $242.8B |
| META PLATFORMS INC-CLASS AMETA | 141 funds | $108.5B |
| NVIDIA CORPNVDA | 140 funds | $369.2B |
| ALPHABET INC-CL AGOOGL | 140 funds | $155.8B |
| INTUITIVE SURGICAL INCISRG | 140 funds | $26.1B |
| MICRON TECHNOLOGY INCMU | 139 funds | $37.8B |
| APPLE INCAAPL | 138 funds | $269.8B |
| BROADCOM INCAVGO | 138 funds | $143.2B |
| LAM RESEARCH CORPLRCX | 137 funds | $31.9B |
| BOSTON SCIENTIFIC CORPBSX | 136 funds | $14.1B |
Ranked by how many of XENE's institutional holders also hold each name, a cross-fund conviction signal.
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| Aug 28, 2026 | KENNEY CHRISTOPHER JOHN | Chief Medical Officer | Sell (S) | 700 | $43K |
| Aug 28, 2026 | KENNEY CHRISTOPHER JOHN | Chief Medical Officer | Sell (S) | 6K | $383K |
| Aug 11, 2026 | GANNON STEVEN | Director | Sell (S) | 10K | $641K |
| Jun 5, 2026 | PATOU GARY | Director | Sell (S) | 1K | $70K |
| Jun 5, 2026 | Cannon Gillian | Director | Sell (S) | 1K | $63K |
| Mar 13, 2026 | MORTIMER IAN | PRESIDENT & CEO, Director | Sell (S) | 7K | $404K |
| Mar 13, 2026 | DiFabio Andrea | Chief Legal Officer | Sell (S) | 1K | $74K |
| Mar 13, 2026 | KENNEY CHRISTOPHER JOHN | Chief Medical Officer | Sell (S) | 1K | $78K |
| Mar 10, 2026 | MORTIMER IAN | PRESIDENT & CEO, Director | Sell (S) | 11K | $677K |
| Mar 10, 2026 | DiFabio Andrea | Chief Legal Officer | Sell (S) | 3K | $157K |
| Mar 10, 2026 | KENNEY CHRISTOPHER JOHN | Chief Medical Officer | Sell (S) | 3K | $167K |
| Mar 9, 2026 | MORTIMER IAN | PRESIDENT & CEO, Director | Sell (S) | 22K | $1.3M |
Connected entities for XENE
This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.
curl -H "Authorization: Bearer YOUR_API_KEY" \ "https://arkolith.com/api/v1/stocks/XENE/capital-change-brief"
Use Arkolith's capital_change_brief for XENE. Tell me what changed, whether insider activity corroborates it, and cite the SEC evidence.
13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for XENE. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.