GPCR

Structure Therapeutics Inc$46.03 7.23%
Health CareUSCUSIP 86366E106· EOD Jul 16, 2026◍ Confluence graph
Tracked 13F Holders
154
-3 QoQ
13F Value (tracked)
$2.7B
Insider Net · 180d
$0
0↑ 0↓
Recent Filings
15
Smart-money sentimentBullish
BearishBullish
13F funds (latest Q)46 adding · 23 trimming
Insider net (180d)$0

Price & smart-money activity

$46.03 7.23%3Y +206.9%
$7.93$30.47$53.01$75.55$98.0920232024202520262187333292126286115393230343234452739446346564732
Hover for who · click for detailEnd-of-day closing prices52w $16.20 – $93.79
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Ask your agent what changed in GPCR

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/GPCR/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for GPCR.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

Top institutional holders

154 tracked 13F filers
1 source-reported value row is withheld because the reported units do not agree with same-security peers. Share counts remain visible and unchanged.
#FundPosition valueSharesLast moveAs ofHistory
1FMR LLC
$405.0M
8.4M
−3.5%
Reduced · −309K sh
Q1 2026
2Avoro Capital Advisors LLC
$316.0M
6.6M
Held
Q1 2026
3JANUS HENDERSON GROUP PLC
$258.3M
5.4M
+5.2%
Added · +265K sh
Q1 2026
4Deep Track Capital, LP
$206.3M
4.3M
+4.1%
Added · +168K sh
Q1 2026
5BVF INC/IL
$166.7M
3.5M
−0.6%
Reduced · −20K sh
Q1 2026
6MORGAN STANLEY
$111.1M
2.3M
+10%
Added · +218K sh
Q1 2026
7PRICE T ROWE ASSOCIATES INC /MD/
$96.4M
2.0M
+20%
Added · +330K sh
Q1 2026
8PRINCIPAL FINANCIAL GROUP INC
$84.5M
1.8M
+37%
Added · +470K sh
Q1 2026
9ORBIMED ADVISORS LLC
$71.1M
1.5M
+27%
Added · +314K sh
Q1 2026
10AMERICAN CENTURY COMPANIES INC
$69.3M
1.4M
+184%
Added · +931K sh
Q1 2026
11BAKER BROS. ADVISORS LP
$69.0M
1.4M
Held
Q1 2026
12Siren, L.L.C.
$64.0M
1.3M
+23%
Added · +250K sh
Q1 2026
13Casdin Capital, LLC
$56.6M
1.2M
Held
Q1 2026
14CAPITOLIS LIQUID GLOBAL MARKETS LLC
$55.5M
1.2M
+31%
Added · +273K sh
Q1 2026
15DEERFIELD MANAGEMENT COMPANY, L.P.
$37.0M
768K
Held
Q1 2026
16PACIFIC HEIGHTS ASSET MANAGEMENT LLC
$36.1M
750K
+7.1%
Added · +50K sh
Q1 2026
17Rock Springs Capital Management LP
$30.9M
640K
−14%
Reduced · −108K sh
Q1 2026
18ALLIANCEBERNSTEIN L.P.
$44.4M
639K
−25%
Reduced · −210K sh
Q1 2026
19Paradigm Biocapital Advisors LP
$26.3M
545K
New
+545K sh
Q1 2026
20FRANKLIN RESOURCES INC
$25.6M
532K
−39%
Reduced · −339K sh
Q1 2026
21Logos Global Management LP
$24.1M
500K
−17%
Reduced · −100K sh
Q1 2026
22HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND
$22.5M
468K
Held
Q1 2026
23BlackRock, Inc.
$21.3M
442K
+2.8%
Added · +12K sh
Q1 2026
24Aberdeen Group plc
$18.9M
392K
+48%
Added · +127K sh
Q1 2026
25DEUTSCHE BANK AG\
$16.0M
332K
−61%
Reduced · −509K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Fund activity: latest quarter

Opened (NEW)
13
funds
Added
33
funds
Reduced
23
funds
Exited
0
funds

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$0
0 insiders
Net
$0
0 P/S txns
Signal
Mixed
open-market
DateInsiderRoleActionSharesValue
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICEROption exercise (M)24K$8K
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICERConversion (C)24K$0
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICEROption exercise (M)24K$0
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICERConversion (C)8K$0
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICERSell (S)6K$319K
Jul 14, 2026Lin XichenCHIEF SCIENTIFIC OFFICERSell (S)2K$83K
Jun 25, 2026Lin XichenCHIEF SCIENTIFIC OFFICEROption exercise (M)24K$8K
Jun 25, 2026Lin XichenCHIEF SCIENTIFIC OFFICERConversion (C)24K$0
Jun 25, 2026Lin XichenCHIEF SCIENTIFIC OFFICEROption exercise (M)24K$0
Jun 25, 2026Lin XichenCHIEF SCIENTIFIC OFFICERConversion (C)8K$0
Jun 25, 2026Lin XichenCHIEF SCIENTIFIC OFFICERSell (S)8K$387K
Jun 17, 2026Russell Angus C.DirectorGrant (A)39K$0

Institutional ownership over time

151 funds+45 since Q3 2024
077154Q3 2024Q1 2025Q3 2025Q1 2026
funds holding aggregate valuelatest $2.7B · 1 values withheld

Funds that own GPCR also own

CompanyCo-held byCombined value
ELI LILLY & COLLY54 funds$5.6B
INTUITIVE SURGICAL INCISRG54 funds$2.4B
BOSTON SCIENTIFIC CORPBSX54 funds$1.8B
MICROSOFT CORPMSFT52 funds$20.4B
AMAZON.COM INCAMZN52 funds$18.5B
DANAHER CORPDHR51 funds$2.1B
GILEAD SCIENCES INCGILD51 funds$1.9B
SERVICENOW INCNOW51 funds$1.5B
NVIDIA CORPNVDA50 funds$26.8B
UNITEDHEALTH GROUP INCUNH50 funds$2.1B
STRYKER CORPSYK50 funds$1.1B
ALPHABET INC-CL AGOOGL49 funds$14.2B

Ranked by how many of GPCR's institutional holders also hold each name, a cross-fund conviction signal. Via the MCP server (ticker.co_held).

Recent filings

15 shown

Browse more

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for GPCR. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes. Every panel above is one call to the Arkolith API & MCP server.