Arkolith/Funds/SR One Capital Management, LP

SR One Capital Management, LP

CIK 1910264Hedge fund
Holdings as of Jun 30, 2026·disclosed Aug 12, 2026·~43-day 13F lag·13F-HR
Active Filer

SR One Capital Management, LP holds a concentrated book of 15 stocks worth $1.0B as of Q2 2026 (disclosed Aug 12, 2026, a ~43-day 13F lag). This quarter they opened Avalyn Pharma Inc. Their largest long position is Veradermics Inc at 28% of the equity book.

Opened
3
bought for the first time
Added to
1
already held, bought more
Trimmed
0
sold some, still holds it
no trims
Sold out
2
exited the position entirely

Concentration

Top-heavy: concentrated book

Top 5 holdings
71%
Top 10 holdings
95%
Top 20 holdings
100%

Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.

Direct sector allocation

90% mapped to company sectors

Health Care
90%
ETF / fund or unclassified
10%

Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.

Biggest moves: latest quarter

Estimated $ traded · quarter-end prices, no cost basis

Bought
Trimmed / exited

Funds with the most overlap

Other tracked managers holding the same core names as SR One Capital Management, LP

Manager / fundShared namesTheir $ in those
GEODE CAPITAL MANAGEMENT, LLC15 / 15$622.0M
Ken Griffin14 / 15$317.9M
UBS Group AG14 / 15$255.8M
MORGAN STANLEY14 / 15$245.0M
JPMORGAN CHASE & CO14 / 15$182.2M
NORTHERN TRUST CORP14 / 15$152.7M
CITIGROUP INC14 / 15$12.9M
FMR LLC13 / 15$965.1M

Ranked by how many of SR One Capital Management, LP's top 15 disclosed names each fund also holds: a cross-fund conviction signal from the latest 13F of every tracked manager.

Holdings: largest first

Bars show each stock's share of the portfolio. Click a row for its position history.

15 positions
#SecurityValueShares% PortLast moveHistory
1Veradermics, Inc.
Common Stock
$295.3M2.40M
28.4%
Held
2Zenas BioPharma, Inc
Common Stock
$127.9M5.04M
12.3%
Held
3CRISPR Therapeutics AG
Common Shares
$111.2M2.04M
10.7%
Held
4Avalyn Pharma, Inc
Common Stock
$108.9M3.31M
10.5%
New
New position
5Design Therapeutics, Inc.
Common Stock
$94.4M6.53M
9.1%
Held
6Odyssey Therapeutics, Inc.
Common Stock
$71.0M3.79M
6.8%
New
New position
7Alumis Inc.
Common Stock
$55.2M1.96M
5.3%
Held
8ORIC Pharmaceuticals, Inc.
Common Stock
$50.0M4.62M
4.8%
+2.2%
Added · +100K sh
9Mineralys Therapeutics Inc.
Common Stock
$42.2M1.56M
4.1%
Held
10ARS Pharmaceuticals, Inc.
Common Stock
$32.1M4.01M
3.1%
Held
11Mobia Medical, Inc
Common Stock
$26.6M1.99M
2.6%
New
New position
12Nkarta, Inc.
Common Stock
$9.4M3.33M
0.9%
Held
13Oculis Holding AG
Ordinary Shares
$8.9M641.0K
0.9%
Held
14Ultragenyx Pharmaceutical Inc.
Common Stock
$4.6M137.8K
0.4%
Held
15enGene Holdings Inc.
Common Shares
$1.3M747.8K
0.1%
Held
Showing all 15 positions
Build

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Filing history

As-of date vs the date the SEC received each filing

QuarterAs ofFiledPositionsValueForm
Q2 2026Jun 30, 2026Aug 12, 202615$1.0B13F-HR
Q1 2026Mar 31, 2026May 14, 202614$915.4M13F-HR
Q4 2025Nov 12, 2025Nov 12, 202512$691.4M13F-HR
Amended / restated
  • Q1 2026 · filed Feb 12, 202613F-HR · superseded

Data source

Holdings from SEC EDGAR 13F-HR filings, updated quarterly, filed up to 45 days after quarter-end. Public domain. The book and weighting are long equity only; disclosed put/call options are listed separately and excluded from those totals. Price-derived performance is withheld until the price-source policy and freshness gate are green.