DSGN

Design Therapeutics Inc
Health CareUSCUSIP 25056L103◍ Confluence graph
Tracked 13F Holders
127
-71 QoQ
13F Value (tracked)
$494.6M
Insider Net · 180d
$0
0↑ 0↓
Recent Filings
15
Smart-money sentimentBullish
BearishBullish
13F funds (latest Q)38 adding · 11 trimming
Insider net (180d)$0

Who owns DSGN?

127 tracked 13F filers

127 tracked 13F filers disclose a position in DSGN as of the latest SEC 13F filings, a combined $494.6M in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

All quarters use one ordinary-share-equivalent series. Historical ADS are converted at 2 ADS = 1 ordinary share. Expand a row for the exact calculation; the residual is not classified as a trade.
#FundPosition valueSharesLast moveAs ofHistory
1SR ONE CAPITAL MANAGEMENT, LP
$94.4M
6.5M
Held
Q2 2026
2RA CAPITAL MANAGEMENT, L.P.
$31.6M
3.0M
+103%
Added · +1.5M sh
Q1 2026
3BAKER BROS. ADVISORS LP
$27.5M
2.6M
+16%
Added · +353K sh
Q1 2026
4Point72 Asset Management, L.P.
$34.2M
2.4M
−13%
Reduced · −356K sh
Q2 2026
5BlackRock, Inc.
$22.7M
2.1M
+0.8%
Added · +17K sh
Q1 2026
6Trails Edge Capital Partners, LP
$29.0M
2.0M
+135%
Added · +1.1M sh
Q2 2026
7Logos Global Management LP
$20.7M
1.9M
−22%
Reduced · −550K sh
Q1 2026
8Frazier Life Sciences Management, L.P.
$26.2M
1.8M
Added
Added · +1.8M sh
Q2 2026
9Vivo Capital, LLC
$23.3M
1.6M
Held
Q2 2026
10VANGUARD CAPITAL MANAGEMENT LLC
$14.4M
1.3M
First observed position
No prior filed position
Q1 2026
11Almitas Capital LLC
$14.9M
1.0M
−33%
Reduced · −503K sh
Q2 2026
12Woodline Partners LP
$10.2M
962K
+1.8%
Added · +17K sh
Q1 2026
13GEODE CAPITAL MANAGEMENT, LLC
$13.9M
958K
+38%
Added · +266K sh
Q2 2026
14Sofinnova Investments, Inc.
$12.5M
865K
New
+865K sh
Q2 2026
15FMR LLC
$8.5M
798K
+3.5%
Added · +27K sh
Q1 2026
16Kynam Capital Management, LP
$8.3M
785K
Held
Q1 2026
17STATE STREET CORP
$10.7M
736K
+12%
Added · +77K sh
Q2 2026
18MORGAN STANLEY
$7.0M
657K
−6.5%
Reduced · −46K sh
Q1 2026
19Siren, L.L.C.
$7.6M
523K
New
+523K sh
Q2 2026
20GOLDMAN SACHS GROUP INC
$5.4M
505K
+86%
Added · +234K sh
Q1 2026
21D. E. Shaw & Co., Inc.
$5.0M
470K
+7.1%
Added · +31K sh
Q1 2026
22DIMENSIONAL FUND ADVISORS LP
$4.6M
432K
+45%
Added · +134K sh
Q1 2026
23RENAISSANCE TECHNOLOGIES LLC
$4.3M
408K
+42%
Added · +121K sh
Q1 2026
24NORTHERN TRUST CORP
$3.2M
300K
+4.8%
Added · +14K sh
Q1 2026
25ALGERT GLOBAL LLC
$4.3M
296K
+45%
Added · +91K sh
Q2 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Is DSGN being bought or sold by institutions?

Last quarter, 12 funds opened a new position in DSGN and 26 added to an existing one, while 11 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).

Opened (NEW)
12
funds
Added
26
funds
Reduced
11
funds
Exited
0
funds

Funds that own DSGN also own

CompanyCo-held byCombined value
ELI LILLY & COLLY53 funds$37.5B
BRISTOL-MYERS SQUIBB COBMY51 funds$7.2B
NVIDIA CORPNVDA50 funds$195.0B
INSMED INCINSM50 funds$4.4B
UNITED THERAPEUTICS CORPUTHR50 funds$3.1B
RHYTHM PHARMACEUTICALS INCRYTM50 funds$2.0B
CYTOKINETICS INCCYTK50 funds$918.0M
WAVE LIFE SCIENCES LTDWVE50 funds$390.3M
NURIX THERAPEUTICS INCNRIX50 funds$312.6M
MICROSOFT CORPMSFT49 funds$129.4B
AMAZON.COM INCAMZN49 funds$91.2B
COGENT BIOSCIENCES INCCOGT49 funds$959.0M

Ranked by how many of DSGN's institutional holders also hold each name, a cross-fund conviction signal.

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$0
0 insiders
Net
$0
0 P/S txns
Signal
Mixed
open-market
DateInsiderRoleActionSharesValue
Aug 13, 2025William ArsaniDirectorSell (S)218K$1.1M
Aug 13, 2025William ArsaniDirectorSell (S)345K$1.8M
Dec 18, 2024Prasad DeepaDirectorSell (S)4K$24K
Aug 9, 2024William ArsaniDirectorSell (S)815K$3.5M
Mar 25, 2024Berger Heather A.DirectorBuy (P)1K$5K
Mar 25, 2024Schmid John P.DirectorBuy (P)18K$67K
Mar 22, 2024Schmid John P.DirectorBuy (P)9K$33K
Sep 29, 2023LAPPE RODNEY WDirectorBuy (P)21K$49K
Aug 29, 2023William ArsaniDirectorBuy (P)2.0M$4.8M
Aug 29, 2023Prasad DeepaDirectorBuy (P)12K$28K
Aug 28, 2023William ArsaniDirectorBuy (P)275K$591K
Dec 20, 2022SR ONE CAPITAL PARTNERS I, LP10% OwnerBuy (P)40K$326K

Institutional ownership over time

43 funds-34 since Q3 2024
057114Q3 2024Q1 2025Q3 2025Q1 2026Q2 2026
funds holding aggregate valuelatest $159.1M

Recent filings

15 shown

Keep exploring

Connected entities for DSGN

Browse more

Build

Ask your agent what changed in DSGN

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/DSGN/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for DSGN.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for DSGN. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.