DFTX

Definium Therapeutics Inc
Health CareUSCUSIP 24477V105◍ Confluence graph
Tracked 13F Holders
287
-59 QoQ
13F Value (tracked)
$2.1B
Insider Net · 180d
-$3.4M
0↑ 5↓
Recent Filings
15
Smart-money sentimentMixed
BearishBullish
13F funds (latest Q)56 adding · 8 trimming
Insider net (180d)-$3.4M

Who owns DFTX?

287 tracked 13F filers

287 tracked 13F filers disclose a position in DFTX as of the latest SEC 13F filings, a combined $2.1B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

All quarters use one ordinary-share-equivalent series. Historical ADS are converted at 2 ADS = 1 ordinary share. Expand a row for the exact calculation; the residual is not classified as a trade.
#FundPosition valueSharesLast moveAs ofHistory
1BlackRock, Inc.
$160.3M
8.5M
New
+8.5M sh
Q1 2026
2Avoro Capital Advisors LLC
$338.2M
7.2M
+44%
Added · +2.2M sh
Q2 2026
3GEODE CAPITAL MANAGEMENT, LLC
$171.5M
3.6M
+46%
Added · +1.1M sh
Q2 2026
4JANUS HENDERSON GROUP PLC
$67.2M
3.6M
New
+3.6M sh
Q1 2026
5STATE STREET CORP
$144.2M
3.1M
+24%
Added · +594K sh
Q2 2026
6Deep Track Capital, LP
$56.7M
3.0M
New
+3.0M sh
Q1 2026
7Octagon Capital Advisors LP
$46.1M
2.4M
New
+2.4M sh
Q1 2026
8Commodore Capital LP
$37.8M
2.0M
New
+2.0M sh
Q1 2026
9FMR LLC
$34.2M
1.8M
New
+1.8M sh
Q1 2026
10GOLDMAN SACHS GROUP INC
$31.7M
1.7M
New
+1.7M sh
Q1 2026
11ArrowMark Colorado Holdings LLC
$30.1M
1.6M
New
+1.6M sh
Q1 2026
12Siren, L.L.C.
$66.8M
1.4M
+54%
Added · +500K sh
Q2 2026
13CITADEL ADVISORS LLC
$25.2M
1.3M
New
+1.3M sh
Q1 2026
14BALYASNY ASSET MANAGEMENT L.P.
$24.1M
1.3M
New
+1.3M sh
Q1 2026
15TWO SIGMA INVESTMENTS, LP
$22.7M
1.2M
New
+1.2M sh
Q1 2026
16MARSHALL WACE, LLP
$22.7M
1.2M
−60%
Reduced · −1.8M sh
Q1 2026
17ADAGE CAPITAL PARTNERS GP, L.L.C.
$21.7M
1.1M
New
+1.1M sh
Q1 2026
18VANGUARD CAPITAL MANAGEMENT LLC
$20.7M
1.1M
First observed position
No prior filed position
Q1 2026
19Holocene Advisors, LP
$20.6M
1.1M
New
+1.1M sh
Q1 2026
20AWM Investment Company, Inc.
$20.4M
1.1M
−23%
Reduced · −314K sh
Q1 2026
21AMERIPRISE FINANCIAL INC
$18.3M
967K
New
+967K sh
Q1 2026
22VANGUARD PORTFOLIO MANAGEMENT LLC
$16.5M
873K
First observed position
No prior filed position
Q1 2026
23MILLENNIUM MANAGEMENT LLC
$16.0M
847K
New
+847K sh
Q1 2026
24CHARLES SCHWAB INVESTMENT MANAGEMENT INC
$15.3M
809K
New
+809K sh
Q1 2026
25ORBIMED ADVISORS LLC
$15.2M
804K
New
+804K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Is DFTX being bought or sold by institutions?

Last quarter, 46 funds opened a new position in DFTX and 10 added to an existing one, while 8 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).

Opened (NEW)
46
funds
Added
10
funds
Reduced
8
funds
Exited
0
funds

Funds that own DFTX also own

CompanyCo-held byCombined value
NVIDIA CORPNVDA140 funds$285.2B
AMAZON.COM INCAMZN138 funds$141.0B
ELI LILLY & COLLY136 funds$60.1B
MICROSOFT CORPMSFT135 funds$184.0B
BROADCOM INCAVGO132 funds$114.2B
ALPHABET INC-CL AGOOGL132 funds$104.8B
MICRON TECHNOLOGY INCMU132 funds$29.9B
META PLATFORMS INC-CLASS AMETA131 funds$81.5B
ADVANCED MICRO DEVICESAMD129 funds$30.5B
APPLE INCAAPL128 funds$209.6B
LAM RESEARCH CORPLRCX127 funds$24.3B
JPMORGAN CHASE & COJPM124 funds$39.8B

Ranked by how many of DFTX's institutional holders also hold each name, a cross-fund conviction signal.

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$3.4M
5 insiders
Net
-$3.4M
8 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jun 25, 2026Sullivan MarkChief Legal OfficerSell (S)13K$586K
Jun 25, 2026Roberts BrandiChief Financial OfficerSell (S)3K$136K
Jun 25, 2026Barrow RobertChief Executive Officer, DirectorSell (S)29K$1.3M
Jun 25, 2026Karlin DanielChief Medical OfficerSell (S)10K$452K
Jun 25, 2026Wiley Matthew T.Chief Commercial OfficerSell (S)3K$129K
Mar 25, 2026Barrow RobertChief Executive Officer, DirectorSell (S)24K$451K
Mar 25, 2026Sullivan MarkChief Legal OfficerSell (S)11K$198K
Mar 25, 2026Karlin DanielChief Medical OfficerSell (S)8K$148K

Institutional ownership over time

158 funds+151 since Q4 2025
0109217Q4 2025Q1 2026Q2 2026
funds holding aggregate valuelatest $1.1B

Recent filings

15 shown

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Connected entities for DFTX

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Ask your agent what changed in DFTX

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/DFTX/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for DFTX.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for DFTX. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.