PRAX

Praxis Precision Medicines I$308.20 3.21%
Health CareUSCUSIP 74006W207· EOD Jul 16, 2026◍ Confluence graph
Tracked 13F Holders
231
+30 QoQ
13F Value (tracked)
$9.7B
Insider Net · 180d
-$3.6M
0↑ 1↓
Recent Filings
15
Smart-money sentimentMixed
BearishBullish
13F funds (latest Q)36 adding · 23 trimming
Insider net (180d)-$3.6M

Price & smart-money activity

$308.20 3.21%5Y +17.2%
$11.10$103.29$195.49$287.68$379.88202120222023202420252026283542743133428262923924374139333934106963192511222
Hover for who · click for detailEnd-of-day closing prices52w $37.70 – $357.13
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Ask your agent what changed in PRAX

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/PRAX/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for PRAX.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

Top institutional holders

231 tracked 13F filers
1 source-reported value row is withheld because the reported units do not agree with same-security peers. Share counts remain visible and unchanged.
#FundPosition valueSharesLast moveAs ofHistory
1JANUS HENDERSON GROUP PLC
$1.1B
3.5M
+6.8%
Added · +219K sh
Q1 2026
2Orbis Allan Gray Ltd
$796.6M
2.5M
+97%
Added · +1.2M sh
Q1 2026
3BlackRock, Inc.
$749.1M
2.3M
+12%
Added · +246K sh
Q1 2026
4FMR LLC
$696.2M
2.2M
+59%
Added · +802K sh
Q1 2026
5PERCEPTIVE ADVISORS LLC
$656.0M
2.0M
+2.0%
Added · +40K sh
Q1 2026
6BAKER BROS. ADVISORS LP
$564.9M
1.8M
+56%
Added · +627K sh
Q1 2026
7VANGUARD CAPITAL MANAGEMENT LLC
$393.7M
1.2M
New
+1.2M sh
Q1 2026
8DEERFIELD MANAGEMENT COMPANY, L.P.
$310.4M
963K
+6.6%
Added · +60K sh
Q1 2026
9Cormorant Asset Management, LP
$285.3M
886K
−6.8%
Reduced · −65K sh
Q1 2026
10STATE STREET CORP
$284.9M
884K
+0.2%
Added · +2K sh
Q1 2026
11MORGAN STANLEY
$268.5M
833K
−6.3%
Reduced · −56K sh
Q1 2026
12ADAGE CAPITAL PARTNERS GP, L.L.C.
$262.8M
816K
−15%
Reduced · −150K sh
Q1 2026
13VANGUARD PORTFOLIO MANAGEMENT LLC
$243.8M
757K
New
+757K sh
Q1 2026
14GOLDMAN SACHS GROUP INC
$229.0M
711K
−0.8%
Reduced · −5K sh
Q1 2026
15GEODE CAPITAL MANAGEMENT, LLC
$209.8M
651K
+16%
Added · +89K sh
Q1 2026
16PRICE T ROWE ASSOCIATES INC /MD/
$203.3M
631K
−20%
Reduced · −155K sh
Q1 2026
17BANK OF AMERICA CORP /DE/
$172.2M
535K
+2.3%
Added · +12K sh
Q1 2026
18RA CAPITAL MANAGEMENT, L.P.
$120.4M
374K
Held
Q1 2026
19Hood River Capital Management LLC
$115.5M
359K
+24%
Added · +69K sh
Q1 2026
20Vivo Capital, LLC
$109.2M
339K
+3.0%
Added · +10K sh
Q1 2026
21Soleus Capital Management, L.P.
$106.5M
331K
−8.9%
Reduced · −32K sh
Q1 2026
22Pictet Asset Management Holding SA
$91.4M
287K
+19%
Added · +46K sh
Q1 2026
23Logos Global Management LP
$91.8M
285K
−24%
Reduced · −90K sh
Q1 2026
24FRANKLIN RESOURCES INC
$89.0M
276K
−22%
Reduced · −80K sh
Q1 2026
25NORTHERN TRUST CORP
$73.4M
228K
+19%
Added · +36K sh
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Fund activity: latest quarter

Opened (NEW)
3
funds
Added
33
funds
Reduced
23
funds
Exited
0
funds

Insider activity (Form 4)

Full insider page →
Buys · 180d
$0
0 insiders
Sells · 180d
$3.6M
1 insiders
Net
-$3.6M
12 P/S txns
Signal
Net Selling
open-market
DateInsiderRoleActionSharesValue
Jul 8, 2026Souza MarcioChief Executive Officer, DirectorGift (G)21K$0
Jul 8, 2026Souza MarcioChief Executive Officer, DirectorGift (G)3K$0
Jun 24, 2026DeSimone JillDirectorOption exercise (M)9K$379K
Jun 24, 2026DeSimone JillDirectorOption exercise (M)3K$447K
Jun 24, 2026DeSimone JillDirectorSell (S)10$3K
Jun 24, 2026DeSimone JillDirectorSell (S)120$36K
Jun 24, 2026DeSimone JillDirectorSell (S)320$98K
Jun 24, 2026DeSimone JillDirectorSell (S)683$210K
Jun 24, 2026DeSimone JillDirectorSell (S)1K$382K
Jun 24, 2026DeSimone JillDirectorSell (S)999$309K
Jun 24, 2026DeSimone JillDirectorSell (S)2K$544K
Jun 24, 2026DeSimone JillDirectorSell (S)3K$890K

Institutional ownership over time

230 funds+131 since Q3 2024
0115230Q3 2024Q1 2025Q3 2025Q1 2026
funds holding aggregate valuelatest $9.7B · 1 values withheld

Funds that own PRAX also own

CompanyCo-held byCombined value
BOSTON SCIENTIFIC CORPBSX80 funds$2.3B
NVIDIA CORPNVDA78 funds$60.1B
MICROSOFT CORPMSFT78 funds$40.6B
ELI LILLY & COLLY77 funds$11.8B
UNITEDHEALTH GROUP INCUNH76 funds$3.4B
AMAZON.COM INCAMZN75 funds$29.3B
ALPHABET INC-CL AGOOGL75 funds$26.2B
BROADCOM INCAVGO75 funds$22.3B
META PLATFORMS INC-CLASS AMETA75 funds$18.0B
INTUITIVE SURGICAL INCISRG75 funds$3.3B
MICRON TECHNOLOGY INCMU74 funds$7.8B
DANAHER CORPDHR74 funds$1.8B

Ranked by how many of PRAX's institutional holders also hold each name, a cross-fund conviction signal. Via the MCP server (ticker.co_held).

Recent filings

15 shown

Browse more

13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for PRAX. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes. Every panel above is one call to the Arkolith API & MCP server.