Affinity Asset Advisors, LLC holds a diversified book of 93 stocks worth $1.7B as of Q1 2026 (disclosed May 14, 2026, a ~45-day 13F lag). This quarter they opened HELIX ACQUISITION CORP III and trimmed SPYRE THERAPEUTICS INC. Their largest long position is APOGEE THERAPEUTICS INC at 6% of the equity book. They also disclosed $149.4M in put options (a bearish bet) and $81.9M in call options (bullish), shown separately below and excluded from the equity book.
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Use Arkolith to show Affinity Asset Advisors, LLC's latest holdings, largest changes, and filing provenance.
Top-heavy: diversified book
Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.
31% mapped to company sectors
Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.
Estimated $ traded · quarter-end prices, no cost basis
Bars show each stock's share of the portfolio. Click a row for its position history.
| # | Security | Value | Shares | % Port | Last move | History |
|---|---|---|---|---|---|---|
| 1 | Apogee Therapeutics Inc COM | $108.2M | 1.28M | 6.3% | ▲+4.0% Added · +50K sh | |
| 2 | Xenon Pharmaceuticals Inc COM | $97.4M | 1.68M | 5.7% | ▲+34% Added · +425K sh | |
| 3 | Erasca Inc COM | $86.6M | 5.35M | 5.1% | ▲+37% Added · +1.4M sh | |
| 4 | Insmed Inc COM PAR $.01 | $78.5M | 480.0K | 4.6% | ▲+6.7% Added · +30K sh | |
| 5 | Roivant Sciences Ltd SHS | $77.6M | 2.80M | 4.5% | ▲+65% Added · +1.1M sh | |
| 6 | Spyre Therapeutics Inc COM NEW | $64.5M | 1.28M | 3.8% | ▼−11% Reduced · −153K sh | |
| 7 | Centessa Pharmaceuticals PLC SPONSORED ADS | $55.6M | 1.40M | 3.3% | ▲+133% Added · +799K sh | |
| 8 | Praxis Precision Medicines I COM NEW | $54.8M | 170.0K | 3.2% | ▼−8.1% Reduced · −15K sh | |
| 9 | Anaptysbio Inc COM | $52.1M | 940.0K | 3.1% | ▲+111% Added · +495K sh | |
| 10 | Alkermes PLC SHS | $47.7M | 1.35M | 2.8% | ▲+35% Added · +350K sh | |
| 11 | Cytokinetics Inc COM NEW | $46.2M | 700.5K | 2.7% | ▼−12% Reduced · −100K sh | |
| 12 | Abivax Sa SPONSORED ADS | $45.1M | 405.0K | 2.6% | ▼−20% Reduced · −100K sh | |
| 13 | Teva Pharmaceutical Inds Ltd SPONSORED ADS | $42.2M | 1.40M | 2.5% | —Held | |
| 14 | Arcellx Inc COMMON STOCK | $41.7M | 362.8K | 2.4% | ▼−31% Reduced · −161K sh | |
| 15 | Nuvalent Inc COM | $30.7M | 300.0K | 1.8% | ▼−7.0% Reduced · −23K sh | |
| 16 | Terns Pharmaceuticals Inc COM | $29.7M | 562.6K | 1.7% | ▲+2.3% Added · +13K sh | |
| 17 | Dianthus Therapeutics Inc COM | $29.4M | 350.0K | 1.7% | ▲+204% Added · +235K sh | |
| 18 | Lexeo Therapeutics Inc COM | $29.0M | 5.05M | 1.7% | ▲+58% Added · +1.9M sh | |
| 19 | Cogent Biosciences Inc COM | $28.9M | 750.0K | 1.7% | ▲+114% Added · +400K sh | |
| 20 | Madrigal Pharmaceuticals Inc COM | $28.8M | 55.0K | 1.7% | ▲+77% Added · +24K sh | |
| 21 | Sutro Biopharma Inc COM SHS | $26.6M | 1.07M | 1.6% | ▲+43% Added · +321K sh | |
| 22 | Forte Biosciences Inc COM NEW | $26.2M | 1.01M | 1.5% | ▲+2.3% Added · +22K sh | |
| 23 | Oruka Therapeutics Inc COM | $24.5M | 499.7K | 1.4% | ▼−38% Reduced · −303K sh | |
| 24 | Trevi Therapeutics Inc COM | $23.9M | 2.00M | 1.4% | ▼−7.0% Reduced · −150K sh | |
| 25 | Ovid Therapeutics Inc COM | $23.6M | 10.64M | 1.4% | ▲+49% Added · +3.5M sh | |
| 26 | Enliven Therapeutics Inc COM | $23.0M | 586.9K | 1.3% | ▲Added Added · +587K sh | |
| 27 | Ascendis Pharma A/s SPONSORED ADR | $21.7M | 95.0K | 1.3% | ▲+217% Added · +65K sh | |
| 28 | Mineralys Therapeutics Inc COM | $20.3M | 750.0K | 1.2% | ▲+2.7% Added · +20K sh | |
| 29 | Avalo Therapeutics Inc COM NEW | $20.0M | 1.34M | 1.2% | ▲+28% Added · +290K sh | |
| 30 | Protagonist Therapeutics Inc COM | $18.1M | 172.1K | 1.1% | —Held | |
| 31 | Celldex Therapeutics Inc New COM NEW | $15.9M | 500.0K | 0.9% | ▲+43% Added · +150K sh | |
| 32 | Zura Bio Ltd CLASS A ORD SHS | $15.3M | 2.56M | 0.9% | ▲+41% Added · +751K sh | |
| 33 | Nurix Therapeutics Inc COM | $15.0M | 967.6K | 0.9% | —Held | |
| 34 | Savara Inc COM | $13.7M | 2.51M | 0.8% | ▼−10% Reduced · −285K sh | |
| 35 | Omeros Corp NOTE 9.500% 6/1 | $13.2M | 6.53M | 0.8% | —Held | |
| 36 | Perspective Therapeutics Inc COM NEW | $13.2M | 3.16M | 0.8% | ▲11× Added · +2.9M sh | |
| 37 | Helix Acquisition Corp III USD CL A ORD SHS | $12.7M | 1.25M | 0.7% | ▲New New position | |
| 38 | Arrowhead Pharmaceuticals In COM | $12.5M | 200.0K | 0.7% | ▲+186% Added · +130K sh | |
| 39 | Damora Therapeutics Inc COM NEW | $11.7M | 450.0K | 0.7% | ▲New New position | |
| 40 | Eupraxia Pharmaceuticals Inc COM | $11.5M | 1.59M | 0.7% | ▲+430% Added · +1.3M sh | |
| 41 | Alto Neuroscience Inc COM SHS | $11.2M | 500.0K | 0.7% | ▲New New position | |
| 42 | Bridgebio Pharma Inc COM | $11.1M | 150.0K | 0.7% | ▼−53% Reduced · −170K sh | |
| 43 | Cullinan Therapeutics Inc COM | $11.1M | 781.3K | 0.7% | ▼−60% Reduced · −1.2M sh | |
| 44 | Belite Bio Inc SPONSORED ADS | $10.4M | 65.0K | 0.6% | ▲+225% Added · +45K sh | |
| 45 | Wave Life Sciences Ltd SHS | $10.2M | 1.40M | 0.6% | ▼−48% Reduced · −1.3M sh | |
| 46 | Vera Therapeutics Inc CL A | $10.1M | 250.0K | 0.6% | —Held | |
| 47 | Tyra Biosciences Inc COM | $9.9M | 257.5K | 0.6% | ▲New New position | |
| 48 | Revolution Medicines Inc COM | $9.7M | 100.0K | 0.6% | —Held | |
| 49 | Jade Biosciences Inc COM NEW | $9.0M | 640.0K | 0.5% | ▼−10% Reduced · −75K sh | |
| 50 | Travere Therapeutics Inc COM | $8.9M | 300.0K | 0.5% | —Held |
Put / call positions from the 13F — totals include every disclosed option leg
| Type | Underlying | Notional value | Underlying shares |
|---|---|---|---|
| PUT · bearish | SS SPDR S&P 500 ETF TRUST-USSPY | $130.1M | 200K |
| CALL · bullish | MODERNA INCMRNA | $40.6M | 800K |
| CALL · bullish | BRISTOL-MYERS SQUIBB CO | $18.2M | 300K |
| PUT · bearish | REVOLUTION MEDICINES INC | $9.7M | 100K |
| PUT · bearish | IMMUNITYBIO INC | $9.6M | 1.3M |
| CALL · bullish | NOVO-NORDISK A/S-SPONS ADRNVO | $6.4M | 175K |
| CALL · bullish | UNIQURE NV | $4.9M | 300K |
| CALL · bullish | DIANTHUS THERAPEUTICS INC | $4.2M | 50K |
| CALL · bullish | CG ONCOLOGY INC | $4.1M | 60K |
| CALL · bullish | CELCUITY INC | $3.4M | 30K |
13F filers disclose option positions at the market value of the underlying the contracts reference, not the premium paid. A put is a bearish bet (it gains if the stock falls); a call is bullish. “Underlying shares” is the share count the contracts control, not a share holding. These legs are excluded from the equity book, weighting, concentration and sector figures above.
As-of date vs the date the SEC received each filing
| Quarter | As of | Filed | Positions | Value | Form |
|---|---|---|---|---|---|
| Q1 2026 | Mar 31, 2026 | May 14, 2026 | 105 | $1.9B | 13F-HR |
| Q4 2025 | Dec 31, 2025 | Feb 13, 2026 | 95 | $1.8B | 13F-HR |
| Q3 2025 | Sep 30, 2025 | Nov 13, 2025 | 96 | $1.1B | 13F-HR |
| Q2 2025 | Jun 30, 2025 | Aug 13, 2025 | 91 | $732.2M | 13F-HR |
| Q1 2025 | Mar 31, 2025 | May 14, 2025 | 98 | $1.0B | 13F-HR |
| Q4 2024 | Dec 31, 2024 | Feb 13, 2025 | 85 | $746.0M | 13F-HR |
| Q3 2024 | Sep 30, 2024 | Nov 13, 2024 | 86 | $732.8M | 13F-HR |
| Q2 2024 | Jun 30, 2024 | Aug 14, 2024 | 98 | $867.5M | 13F-HR |
| Q1 2024 | Mar 31, 2024 | May 14, 2024 | 95 | $807.8M | 13F-HR |
| Q4 2023 | Dec 31, 2023 | Feb 13, 2024 | 82 | $547.5M | 13F-HR |
| Q3 2023 | Sep 30, 2023 | Nov 14, 2023 | 81 | $355.5M | 13F-HR |
| Q2 2023 | Jun 30, 2023 | Aug 21, 2023 | 70 | $286.3M | 13F-HR/A |
| Q1 2023 | Mar 31, 2023 | May 15, 2023 | 74 | $303.0M | 13F-HR |
| Q4 2022 | Dec 31, 2022 | Feb 13, 2023 | 63 | $255.0M | 13F-HR |
| Q3 2022 | Sep 30, 2022 | Nov 14, 2022 | 64 | $358.3M | 13F-HR |
| Q2 2022 | Jun 30, 2022 | Aug 12, 2022 | 54 | $237.2M | 13F-HR |
| Q1 2022 | Mar 31, 2022 | May 13, 2022 | 59 | $625.0M | 13F-HR |
| Q4 2021 | Dec 31, 2021 | Feb 11, 2022 | 55 | $275.4M | 13F-HR |
| Q3 2021 | Sep 30, 2021 | Nov 12, 2021 | 73 | $396.0M | 13F-HR |
| Q2 2021 | Jun 30, 2021 | Aug 13, 2021 | 69 | $279.3M | 13F-HR |
| Q1 2021 | Mar 31, 2021 | May 14, 2021 | 72 | $294.5M | 13F-HR |
| Q4 2020 | Dec 31, 2020 | Feb 12, 2021 | 62 | $188.7M | 13F-HR |
Holdings from SEC EDGAR 13F-HR filings, updated quarterly ~45 days after quarter-end. Public domain. The book and weighting are long equity only; disclosed put/call options are listed separately and excluded from those totals. The performance line is a simulation of the disclosed long book, not an audited return.