Arkolith/Funds/TCG Crossover Management, LLC

TCG Crossover Management, LLC

CIK 1839948Hedge fund
Holdings as of Mar 31, 2026·disclosed May 15, 2026·~45-day 13F lag·13F-HR
Active Filer

TCG Crossover Management, LLC holds a focused book of 49 stocks worth $3.5B as of Q1 2026 (disclosed May 15, 2026, a ~45-day 13F lag). This quarter they opened Biocryst Pharmaceuticals Inc and trimmed Abivax Sa-ADR. Their largest long position is Abivax Sa-ADR at 21% of the equity book.

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holdings, largest changes, and filing provenance.
Opened
11
new positions
Added to
8
existing
Trimmed
10
reduced
Sold out
5
exited

Concentration

Top-heavy: focused book

Top 5 holdings
44%
Top 10 holdings
61%
Top 20 holdings
82%

Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.

Direct sector allocation

100% mapped to company sectors

Health Care
100%

Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.

Biggest moves: latest quarter

Estimated $ traded · quarter-end prices, no cost basis

Bought
Trimmed / exited

Holdings: largest first

Bars show each stock's share of the portfolio. Click a row for its position history.

49 positions
#SecurityValueShares% PortLast moveHistory
1Abivax Sa American Depositary Shares
ADRS
$721.7M6.48M
20.6%
−8.9%
Reduced · −631K sh
2CG Oncology Inc
COMM
$248.4M3.67M
7.1%
Held
3Tango Therapeutics Inc
COMM
$220.3M10.53M
6.3%
−17%
Reduced · −2.2M sh
4Cogent Biosciences Inc
COMM
$190.4M4.95M
5.4%
−16%
Reduced · −921K sh
5Centessa Pharmaceuticals PLC
ADRS
$170.3M4.29M
4.9%
Held
6Dianthus Therapeutics Inc
COMM
$140.7M1.68M
4.0%
Held
7Tyra Biosciences Inc
COMM
$124.4M3.25M
3.6%
+12%
Added · +351K sh
8Immunovant Inc
COMM
$110.7M4.46M
3.2%
+168%
Added · +2.8M sh
9Biocryst Pharmaceuticals Inc
COMM
$104.9M11.02M
3.0%
New
New position
10Mirum Pharmaceuticals Inc
COMM
$98.1M1.06M
2.8%
17×
Added · +1.0M sh
11Vor Biopharma Inc
COMM
$96.5M5.67M
2.8%
New
New position
12Spyre Therapeutics Inc
COMM
$95.9M1.90M
2.7%
Held
13Amylyx Pharmaceuticals Inc
COMM
$86.8M6.24M
2.5%
Held
14Disc Medicine Inc
COMM
$85.8M1.34M
2.5%
New
New position
15Dyne Therapeutics Inc
COMM
$83.7M4.62M
2.4%
Held
16Monte Rosa Therapeutics Inc
COMM
$76.0M4.62M
2.2%
Held
17Savara Inc
COMM
$67.5M12.36M
1.9%
Held
18Revolution Medicines Inc
COMM
$56.1M576.5K
1.6%
+32%
Added · +140K sh
19Kodiak Sciences Inc
COMM
$55.1M1.45M
1.6%
Held
20LB Pharmaceuticals Inc
COMM
$45.3M1.84M
1.3%
+5.4%
Added · +94K sh
21Surrozen Inc
COMM
$42.9M1.47M
1.2%
New
New position
22Adc Therapeutics Sa
COMM
$42.7M11.39M
1.2%
Held
23Relay Therapeutics Inc
COMM
$42.5M4.27M
1.2%
+33%
Added · +1.1M sh
24Fulcrum Therapeutics Inc
COMM
$40.3M5.25M
1.2%
Held
25Biohaven Ltd
COMM
$39.2M4.63M
1.1%
Held
26Century Therapeutics Inc
COMM
$39.0M17.75M
1.1%
New
New position
27Tectonic Therapeutic Inc
COMM
$37.2M1.20M
1.1%
New
New position
28Perspective Therapeutics Inc
COMM
$33.0M7.92M
0.9%
New
New position
29Xencor Inc
COMM
$29.6M2.45M
0.8%
Held
30Entrada Therapeutics Inc
COMM
$28.9M2.29M
0.8%
+9.5%
Added · +199K sh
31Alx Oncology Holdings Inc
COMM
$26.1M13.01M
0.7%
New
New position
32Arvinas Holding Co LLC
COMM
$25.3M2.39M
0.7%
−10%
Reduced · −279K sh
33Janux Therapeutics Inc
COMM
$24.9M1.79M
0.7%
Held
34Agomab Therapeutics NV
ADRS
$21.5M2.05M
0.6%
New
New position
35Alector Inc
COMM
$21.5M10.00M
0.6%
Held
36MBX Biosciences Inc
COMM
$19.4M650.0K
0.6%
Held
37Silence Therapeutics PLC
ADRS
$16.0M3.03M
0.5%
Held
38Liquidia Technologies Inc
COMM
$15.2M403.0K
0.4%
−76%
Reduced · −1.3M sh
39Ocular Therapeutix Inc
COMM
$14.0M1.65M
0.4%
−71%
Reduced · −4.1M sh
40Avalo Therapeutics Inc
COMM
$11.0M738.4K
0.3%
+53%
Added · +255K sh
41Urogen Pharma Ltd
COMM
$7.3M405.4K
0.2%
−43%
Reduced · −312K sh
42Monopar Therapeutics Inc
COMM
$7.2M132.1K
0.2%
−6.9%
Reduced · −10K sh
43Context Therapeutics Inc
COMM
$7.0M2.68M
0.2%
New
New position
44Structure Therapeutics Inc
ADRS
$6.8M140.4K
0.2%
−85%
Reduced · −780K sh
45Cullinan Therapeutics Inc
COMM
$5.8M406.8K
0.2%
New
New position
46Korro Bio Inc
COMM
$4.7M416.3K
0.1%
Held
47Leonabio Inc
COMM
$4.7M464.4K
0.1%
Held
48Upstream Bio Inc
COMM
$1.6M181.1K
0.0%
−76%
Reduced · −563K sh
49Vistagen Therapeutics Inc
COMM
$1.5M2.68M
0.0%
Held
Showing all 49 positions

Filing history

As-of date vs the date the SEC received each filing

QuarterAs ofFiledPositionsValueForm
Q1 2026Mar 31, 2026May 15, 202649$3.5B13F-HR
Q4 2025Dec 31, 2025Feb 17, 202643$3.0B13F-HR
Q3 2025Sep 30, 2025Nov 17, 202540$2.0B13F-HR
Q2 2025Jun 30, 2025Aug 14, 202538$875.5M13F-HR
Q1 2025Mar 31, 2025May 14, 202538$733.1M13F-HR
Q4 2024Dec 31, 2024Feb 14, 202538$1.0B13F-HR
Q3 2024Sep 30, 2024Nov 14, 202436$1.2B13F-HR
Q2 2024Jun 30, 2024Aug 14, 202432$959.5M13F-HR
Q1 2024Mar 31, 2024May 15, 202433$1.3B13F-HR
Q4 2023Dec 31, 2023Feb 14, 202429$901.7M13F-HR
Q3 2023Sep 30, 2023Nov 14, 202326$679.1M13F-HR
Q2 2023Jun 30, 2023Aug 14, 202322$609.8M13F-HR
Q1 2023Mar 31, 2023May 15, 202322$513.0M13F-HR
Q4 2022Dec 31, 2022Feb 14, 202321$566.6M13F-HR
Q3 2022Sep 30, 2022Nov 14, 202221$333.4M13F-HR
Q2 2022Jun 30, 2022Aug 15, 202222$235.4M13F-HR
Q1 2022Mar 31, 2022May 16, 202220$249.1M13F-HR
Q4 2021Dec 31, 2021Feb 18, 202215$213.6M13F-HR

Data source

Holdings from SEC EDGAR 13F-HR filings, updated quarterly ~45 days after quarter-end. Public domain. The book and weighting are long equity only; disclosed put/call options are listed separately and excluded from those totals. Price-derived performance is withheld until the price-source policy and freshness gate are green.