This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.
curl -H "Authorization: Bearer YOUR_API_KEY" \ "https://arkolith.com/api/v1/stocks/TYRA/capital-change-brief"
Use Arkolith's capital_change_brief for TYRA. Tell me what changed, whether insider activity corroborates it, and cite the SEC evidence.
| # | Fund | Position value | Shares | Last move | As of | History |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $467.2M | 12.2M | —Held | Q1 2026 | |
| 2 | FMR LLC | $296.7M | 7.7M | ▲617× Added · +7.7M sh | Q1 2026 | |
| 3 | Nextech Invest, Ltd. | $155.3M | 4.1M | —Held | Q1 2026 | |
| 4 | JANUS HENDERSON GROUP PLC | $148.9M | 3.9M | ▲+33% Added · +955K sh | Q1 2026 | |
| 5 | FARALLON CAPITAL MANAGEMENT LLC | $137.1M | 3.6M | ▲+73% Added · +1.5M sh | Q1 2026 | |
| 6 | TCG Crossover Management, LLC | $124.4M | 3.2M | ▲+12% Added · +351K sh | Q1 2026 | |
| 7 | Commodore Capital LP | $94.8M | 2.5M | ▼−27% Reduced · −900K sh | Q1 2026 | |
| 8 | BlackRock, Inc. | $84.9M | 2.2M | ▲+6.3% Added · +132K sh | Q1 2026 | |
| 9 | Paradigm Biocapital Advisors LP | $78.7M | 2.1M | ▲New +2.1M sh | Q1 2026 | |
| 10 | BVF INC/IL | $75.7M | 2.0M | ▼−7.1% Reduced · −151K sh | Q1 2026 | |
| 11 | Caligan Partners LP | $48.9M | 1.3M | ▲+35% Added · +333K sh | Q1 2026 | |
| 12 | STATE STREET CORP | $46.6M | 1.2M | ▲+62% Added · +467K sh | Q1 2026 | |
| 13 | VANGUARD CAPITAL MANAGEMENT LLC | $43.1M | 1.1M | ▲New +1.1M sh | Q1 2026 | |
| 14 | 5AM Venture Management, LLC | $39.4M | 1.0M | —Held | Q1 2026 | |
| 15 | PRICE T ROWE ASSOCIATES INC /MD/ | $37.8M | 986K | ▲68× Added · +972K sh | Q1 2026 | |
| 16 | Logos Global Management LP | $32.6M | 850K | ▲+305% Added · +640K sh | Q1 2026 | |
| 17 | BARCLAYS PLC | $31.9M | 833K | ▲11× Added · +757K sh | Q1 2026 | |
| 18 | GEODE CAPITAL MANAGEMENT, LLC | $25.2M | 658K | ▲+0.1% Added · +726 sh | Q1 2026 | |
| 19 | JENNISON ASSOCIATES LLC | $24.2M | 632K | ▲New +632K sh | Q1 2026 | |
| 20 | GOLDMAN SACHS GROUP INC | $21.1M | 550K | ▲+202% Added · +368K sh | Q1 2026 | |
| 21 | DEERFIELD MANAGEMENT COMPANY, L.P. | $21.0M | 549K | ▲New +549K sh | Q1 2026 | |
| 22 | BALYASNY ASSET MANAGEMENT L.P. | $13.5M | 351K | ▼−57% Reduced · −467K sh | Q1 2026 | |
| 23 | Woodline Partners LP | $11.5M | 301K | ▲New +301K sh | Q1 2026 | |
| 24 | BOOTHBAY FUND MANAGEMENT, LLC | $10.5M | 273K | ▲+24% Added · +52K sh | Q1 2026 | |
| 25 | Affinity Asset Advisors, LLC | $9.9M | 258K | ▲New +258K sh | Q1 2026 |
Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| May 28, 2026 | Rothenberg Stephen Michael | Director | Grant (A) | 13K | $0 |
| May 28, 2026 | MORE ROBERT J | Director | Grant (A) | 13K | $0 |
| May 28, 2026 | RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | Grant (A) | 13K | $0 |
| May 28, 2026 | Moran Susan | Director | Grant (A) | 13K | $0 |
| May 28, 2026 | Verjee Rehan | Director | Grant (A) | 13K | $0 |
| May 28, 2026 | Gulfo Adele M. | Director | Grant (A) | 13K | $0 |
| May 28, 2026 | Simson Jake | Director | Grant (A) | 13K | $0 |
| May 5, 2026 | Rueb Yuliya | Vice President, Finance (PAO) | Grant (A) | 28K | $0 |
| May 5, 2026 | Rueb Yuliya | Vice President, Finance (PAO) | Grant (A) | 8K | $0 |
| May 5, 2026 | Warner Douglas J | Chief Medical Officer | Grant (A) | 85K | $0 |
| May 5, 2026 | Warner Douglas J | Chief Medical Officer | Grant (A) | 25K | $0 |
| May 5, 2026 | Harris Todd | President and CEO, Director | Grant (A) | 265K | $0 |
| Company | Co-held by | Combined value |
|---|---|---|
| ELI LILLY & COLLY | 43 funds | $4.9B |
| BRISTOL-MYERS SQUIBB COBMY | 43 funds | $1.3B |
| DEXCOM INCDXCM | 43 funds | $457.5M |
| INTUITIVE SURGICAL INCISRG | 42 funds | $2.3B |
| BOSTON SCIENTIFIC CORPBSX | 42 funds | $1.7B |
| UNITED THERAPEUTICS CORPUTHR | 42 funds | $1.2B |
| STRYKER CORPSYK | 42 funds | $913.4M |
| CENTENE CORPCNC | 42 funds | $675.8M |
| BIOGEN INCBIIB | 42 funds | $455.2M |
| MICROSOFT CORPMSFT | 41 funds | $20.4B |
| AMAZON.COM INCAMZN | 41 funds | $16.9B |
| PALANTIR TECHNOLOGIES INC-APLTR | 41 funds | $3.4B |
Ranked by how many of TYRA's institutional holders also hold each name, a cross-fund conviction signal. Via the MCP server (ticker.co_held).
13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for TYRA. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes. Every panel above is one call to the Arkolith API & MCP server.