162 tracked 13F filers disclose a position in TYRA as of the latest SEC 13F filings, a combined $2.5B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
| # | Fund | Position value | Shares | Last move | As of | History |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $467.2M | 12.2M | —Held | Q1 2026 | |
| 2 | FMR LLC | $296.7M | 7.7M | ▲617× Added · +7.7M sh | Q1 2026 | |
| 3 | Nextech Invest Ltd. | $155.3M | 4.1M | —Held | Q1 2026 | |
| 4 | Janus Henderson Group Ltd. | $148.9M | 3.9M | ▲+33% Added · +955K sh | Q1 2026 | |
| 5 | Alta Partners Management Company, L.P. | $122.1M | 3.8M | —Held | Q2 2026 | |
| 6 | FARALLON CAPITAL MANAGEMENT, L.L.C. | $137.1M | 3.6M | ▲+73% Added · +1.5M sh | Q1 2026 | |
| 7 | TCG Crossover Management, LLC | $124.4M | 3.2M | ▲+12% Added · +351K sh | Q1 2026 | |
| 8 | Commodore Capital LP | $94.8M | 2.5M | ▼−27% Reduced · −900K sh | Q1 2026 | |
| 9 | BlackRock, Inc. | $84.9M | 2.2M | ▲+6.3% Added · +132K sh | Q1 2026 | |
| 10 | STATE STREET CORP | $68.4M | 2.1M | ▲+76% Added · +924K sh | Q2 2026 | |
| 11 | Paradigm Biocapital Advisors LP | $78.7M | 2.1M | ▲New +2.1M sh | Q1 2026 | |
| 12 | BVF INC/IL | $75.7M | 2.0M | ▼−7.1% Reduced · −151K sh | Q1 2026 | |
| 13 | Caligan Partners LP | $48.9M | 1.3M | ▲+35% Added · +333K sh | Q1 2026 | |
| 14 | VANGUARD CAPITAL MANAGEMENT LLC | $43.1M | 1.1M | →First observed position No prior filed position | Q1 2026 | |
| 15 | 5AM Venture Management, LLC | $32.9M | 1.0M | —Held | Q2 2026 | |
| 16 | Hood River Capital Management LLC | $32.5M | 1.0M | ▲New +1.0M sh | Q2 2026 | |
| 17 | PRICE T ROWE ASSOCIATES INC /MD/ | $37.8M | 986K | ▲68× Added · +972K sh | Q1 2026 | |
| 18 | GEODE CAPITAL MANAGEMENT, LLC | $31.0M | 971K | ▲+47% Added · +312K sh | Q2 2026 | |
| 19 | Logos Global Management LP | $32.6M | 850K | ▲+305% Added · +640K sh | Q1 2026 | |
| 20 | BARCLAYS PLC | $31.9M | 833K | ▲11× Added · +757K sh | Q1 2026 | |
| 21 | Canaan Partners XI LLC | $24.0M | 750K | —Held | Q2 2026 | |
| 22 | Siren, L.L.C. | $23.2M | 725K | ▲New +725K sh | Q2 2026 | |
| 23 | JENNISON ASSOCIATES LLC | $24.2M | 632K | ▲New +632K sh | Q1 2026 | |
| 24 | GOLDMAN SACHS GROUP INC | $21.1M | 550K | ▲+202% Added · +368K sh | Q1 2026 | |
| 25 | DEERFIELD MANAGEMENT COMPANY, L.P. | $21.0M | 549K | ▲New +549K sh | Q1 2026 |
Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
Last quarter, 17 funds opened a new position in TYRA and 23 added to an existing one, while 13 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).
| Company | Co-held by | Combined value |
|---|---|---|
| AMAZON.COM INCAMZN | 78 funds | $138.0B |
| REVOLUTION MEDICINES INCRVMD | 77 funds | $7.3B |
| NVIDIA CORPNVDA | 76 funds | $279.5B |
| META PLATFORMS INC-CLASS AMETA | 76 funds | $79.8B |
| MICROSOFT CORPMSFT | 75 funds | $184.8B |
| MICRON TECHNOLOGY INCMU | 75 funds | $22.2B |
| ELI LILLY & COLLY | 74 funds | $59.3B |
| BROADCOM INCAVGO | 73 funds | $111.1B |
| COSTCO WHOLESALE CORPCOST | 72 funds | $28.8B |
| APPLIED MATERIALS INCAMAT | 72 funds | $19.8B |
| APPLE INCAAPL | 71 funds | $207.3B |
| ALPHABET INC-CL AGOOGL | 71 funds | $110.8B |
Ranked by how many of TYRA's institutional holders also hold each name, a cross-fund conviction signal.
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| Mar 25, 2026 | KAPLAN GILLA | Director | Sell (S) | 14K | $528K |
| Feb 12, 2026 | Bensen Daniel | Chief Discovery Officer | Sell (S) | 2K | $67K |
| Feb 12, 2026 | Bensen Daniel | Chief Discovery Officer | Sell (S) | 6K | $196K |
| Jan 12, 2026 | Bensen Daniel | Chief Discovery Officer | Sell (S) | 7K | $199K |
| Jan 12, 2026 | Bensen Daniel | Chief Discovery Officer | Sell (S) | 1K | $30K |
| Dec 19, 2025 | MORE ROBERT J | Director | Sell (S) | 10K | $250K |
| Dec 12, 2025 | Bensen Daniel | Chief Discovery Officer | Sell (S) | 8K | $181K |
| Nov 21, 2025 | MORE ROBERT J | Director | Sell (S) | 247K | $5.0M |
| Nov 19, 2025 | Bensen Daniel | Chief Operating Officer | Sell (S) | 50K | $815K |
| Nov 18, 2025 | Bensen Daniel | Chief Operating Officer | Sell (S) | 76K | $1.2M |
| Nov 17, 2025 | Bensen Daniel | Chief Operating Officer | Sell (S) | 2K | $26K |
| Nov 17, 2025 | Bensen Daniel | Chief Operating Officer | Sell (S) | 19K | $299K |
Connected entities for TYRA
This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.
curl -H "Authorization: Bearer YOUR_API_KEY" \ "https://arkolith.com/api/v1/stocks/TYRA/capital-change-brief"
Use Arkolith's capital_change_brief for TYRA. Tell me what changed, whether insider activity corroborates it, and cite the SEC evidence.
13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for TYRA. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.