125 tracked 13F filers disclose a position in SION as of the latest SEC 13F filings, a combined $1.9B in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
| # | Fund | Position value | Shares | Last move | As of | History |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $397.1M | 9.9M | —Held | Q1 2026 | |
| 2 | TPG GP A, LLC | $260.4M | 6.5M | ▼−3.7% Reduced · −250K sh | Q1 2026 | |
| 3 | ORBIMED ADVISORS LLC | $141.5M | 3.5M | ▼−0.9% Reduced · −31K sh | Q1 2026 | |
| 4 | VIKING GLOBAL INVESTORS LP | $128.1M | 3.2M | —Held | Q1 2026 | |
| 5 | Atlas Venture Life Science Advisors, LLC | $131.8M | 3.0M | —Held | Q2 2026 | |
| 6 | Enavate Sciences GP, LLC | $99.3M | 2.5M | —Held | Q1 2026 | |
| 7 | JPMORGAN CHASE & CO | $53.7M | 1.5M | ▲+19% Added · +233K sh | Q1 2026 | |
| 8 | JENNISON ASSOCIATES LLC | $58.2M | 1.5M | ▲+30% Added · +336K sh | Q1 2026 | |
| 9 | BlackRock, Inc. | $52.0M | 1.3M | ▲+0.3% Added · +4K sh | Q1 2026 | |
| 10 | CITADEL ADVISORS LLC | $46.8M | 1.2M | ▲+7.3% Added · +80K sh | Q1 2026 | |
| 11 | VANGUARD CAPITAL MANAGEMENT LLC | $41.3M | 1.0M | →First observed position No prior filed position | Q1 2026 | |
| 12 | STATE STREET CORP | $44.9M | 1.0M | ▲+35% Added · +265K sh | Q2 2026 | |
| 13 | DEERFIELD MANAGEMENT COMPANY, L.P. | $38.9M | 971K | —Held | Q1 2026 | |
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | $30.3M | 756K | ▼−9.0% Reduced · −75K sh | Q1 2026 | |
| 15 | PERCEPTIVE ADVISORS LLC | $26.4M | 658K | ▼−44% Reduced · −521K sh | Q1 2026 | |
| 16 | EVENTIDE ASSET MANAGEMENT, LLC | $25.9M | 646K | ▲+1.0% Added · +6K sh | Q1 2026 | |
| 17 | Siren, L.L.C. | $26.9M | 611K | ▲+104% Added · +311K sh | Q2 2026 | |
| 18 | Aberdeen Group plc | $22.6M | 564K | ▼−33% Reduced · −276K sh | Q1 2026 | |
| 19 | GEODE CAPITAL MANAGEMENT, LLC | $20.1M | 457K | ▲+17% Added · +67K sh | Q2 2026 | |
| 20 | BAKER BROS. ADVISORS LP | $16.0M | 400K | —Held | Q1 2026 | |
| 21 | GOLDMAN SACHS GROUP INC | $10.6M | 263K | ▲+626% Added · +227K sh | Q1 2026 | |
| 22 | Candriam S.C.A. | $10.2M | 233K | ▼−1.5% Reduced · −4K sh | Q2 2026 | |
| 23 | Kalehua Capital Management LLC | $8.7M | 197K | —Held | Q2 2026 | |
| 24 | Ensign Peak Advisors, Inc | $8.1M | 185K | ▼−28% Reduced · −71K sh | Q2 2026 | |
| 25 | Soleus Capital Management, L.P. | $7.8M | 178K | ▼−39% Reduced · −116K sh | Q2 2026 |
Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.
Last quarter, 12 funds opened a new position in SION and 21 added to an existing one, while 18 reduced and 0 exited entirely — based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).
| Company | Co-held by | Combined value |
|---|---|---|
| INSMED INCINSM | 59 funds | $4.2B |
| REVOLUTION MEDICINES INCRVMD | 58 funds | $3.8B |
| RHYTHM PHARMACEUTICALS INCRYTM | 56 funds | $2.5B |
| COGENT BIOSCIENCES INCCOGT | 55 funds | $1.1B |
| ELI LILLY & COLLY | 54 funds | $46.3B |
| BOSTON SCIENTIFIC CORPBSX | 54 funds | $6.5B |
| PRAXIS PRECISION MEDICINES IPRAX | 54 funds | $2.7B |
| ERASCA INCERAS | 54 funds | $501.5M |
| NVIDIA CORPNVDA | 53 funds | $216.1B |
| AMAZON.COM INCAMZN | 53 funds | $107.7B |
| ADVANCED MICRO DEVICESAMD | 53 funds | $20.9B |
| INTUITIVE SURGICAL INCISRG | 53 funds | $17.3B |
Ranked by how many of SION's institutional holders also hold each name, a cross-fund conviction signal.
| Date | Insider | Role | Action | Shares | Value |
|---|---|---|---|---|---|
| Jul 7, 2026 | Thompson Peter A. | Director | Sell (S) | 86K | $3.9M |
| Jul 7, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 86K | $3.9M |
| Jul 6, 2026 | Fitzpatrick Jennifer | Chief Legal Officer | Sell (S) | 10K | $447K |
| Jun 30, 2026 | Thompson Peter A. | Director | Sell (S) | 116K | $5.3M |
| Jun 30, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 116K | $5.3M |
| May 27, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 101 | $4K |
| May 27, 2026 | Thompson Peter A. | Director | Sell (S) | 101 | $4K |
| May 11, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 185K | $8.5M |
| May 11, 2026 | Thompson Peter A. | Director | Sell (S) | 185K | $8.5M |
| May 8, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 60K | $2.7M |
| May 8, 2026 | Thompson Peter A. | Director | Sell (S) | 60K | $2.7M |
| May 7, 2026 | ORBIMED ADVISORS LLC | Director | Sell (S) | 49K | $2.2M |
Connected entities for SION
This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.
curl -H "Authorization: Bearer YOUR_API_KEY" \ "https://arkolith.com/api/v1/stocks/SION/capital-change-brief"
Use Arkolith's capital_change_brief for SION. Tell me what changed, whether insider activity corroborates it, and cite the SEC evidence.
13F holdings + Form 4 insider transactions + end-of-day price history + the live filing stream, joined for SION. Filings are public domain, sourced to SEC EDGAR; price series derived from end-of-day closes.