LXEO

Lexeo Therapeutics Inc Cross-source read
Health CareCUSIP 52886X107

Among active 13F managers last quarter, 5 opened and 24 added, while 16 reduced; the largest holder to move was Paradigm Biocapital Advisors LP (+30%). Over the last 180 days, 4 insiders sold and none bought, a net -$636K in open-market trades.

Tracked 13F holders
133
47 in Q2 2026 filings
13F value (tracked)
$435.0M
Smart-money readMixed
Net sellingNet buying
Funds · active managers, latest 13F
29 adding · 16 trimming
Insiders · Form 4 open-market, 180d
0 buying · 4 selling · -$636K
US House · STOCK Act, 180d
0 buying · 0 selling

The legs disagree, or only one of them leans.

Who owns LXEO?

133 tracked 13F filers · ranked by shares held

133 tracked 13F filers disclose a position in LXEO as of the latest SEC 13F filings, a combined $435.0M in reported value. Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

#FundSharesPosition valueLast moveAs ofHistory
1Paradigm Biocapital Advisors LP6.2M
$35.5M
+30%
Added · +1.4M sh
Q1 2026
2BlackRock, Inc.5.1M
$29.3M
+4.1%
Added · +203K sh
Q1 2026
3Affinity Asset Advisors, LLC5.1M
$29.0M
+58%
Added · +1.9M sh
Q1 2026
4Ra Capital Management, L.P.5.0M
$28.7M
Held
Q1 2026
5Janus Henderson Group Ltd.5.0M
$28.5M
−9.7%
Reduced · −533K sh
Q1 2026
6Frazier Life Sciences Management, L.P.4.8M
$22.5M
+9.0%
Added · +400K sh
Q2 2026
7Vestal Point Capital, LP4.5M
$25.7M
Held
Q1 2026
8State Street Corp4.4M
$20.3M
+22%
Added · +787K sh
Q2 2026
9Citadel Advisors LLC3.9M
$18.1M
+1.6%
Added · +64K sh
Q2 2026
10Orbimed Advisors LLC3.6M
$20.7M
+70%
Added · +1.5M sh
Q1 2026
11Vanguard Capital Management LLC3.0M
$17.3M
New filer
Inherited book · not a new buyer
Q1 2026
12Woodline Partners LP2.8M
$15.8M
−14%
Reduced · −447K sh
Q1 2026
13Goldman Sachs Group Inc1.9M
$11.2M
+149%
Added · +1.2M sh
Q1 2026
14683 Capital Management, LLC1.9M
$8.7M
+56%
Added · +675K sh
Q2 2026
15Geode Capital Management, LLC1.7M
$8.1M
+15%
Added · +234K sh
Q2 2026
16Millennium Management LLC1.6M
$9.3M
+78%
Added · +705K sh
Q1 2026
17Balyasny Asset Management L.P.1.6M
$9.1M
−2.8%
Reduced · −45K sh
Q1 2026
18Avoro Capital Advisors LLC1.5M
$6.9M
−21%
Reduced · −386K sh
Q2 2026
19ADAR1 Capital Management, LLC1.5M
$8.4M
+5.3%
Added · +74K sh
Q1 2026
20Nantahala Capital Management, LLC1.3M
$6.1M
+8.3%
Added · +100K sh
Q2 2026
21Montanova Capital, LLC1.3M
$7.2M
Held
Q1 2026
22Dimensional Fund Advisors LP1.1M
$6.3M
+28%
Added · +241K sh
Q1 2026
23Octagon Capital Advisors LP1.1M
$6.3M
−36%
Reduced · −625K sh
Q1 2026
24Spruce Street Capital LP929K
$4.3M
Held
Q2 2026
25Blackstone Inc.905K
$5.2M
Held
Q1 2026

Holders and values reflect the 13F filers Arkolith currently tracks, not the entire institutional universe. Counts and totals are a floor, not the full institutional ownership.

Is LXEO being bought or sold by institutions?

Last quarter, 5 funds opened a new position in LXEO and 24 added to an existing one, while 16 reduced. Based on 13F filings from active, signal-eligible managers (passive index funds and other mechanical holders are excluded from this count).

Opened
5
funds took a first position
Added
24
added to an existing position
Reduced
16
reduced, still holding
Biggest moves · ranked by size of the change, positions above a floor

Funds that own LXEO also own

CompanyCo-held byTheir position there
Amazon.com IncAMZN59 funds$99.4B
Nvidia CorpNVDA57 funds$210.1B
Eli Lilly & CoLLY57 funds$42.2B
Microsoft CorpMSFT56 funds$140.7B
Alphabet Inc-CL AGOOGL56 funds$74.3B
Meta Platforms Inc-Class AMETA56 funds$60.4B
Advanced Micro DevicesAMD56 funds$17.8B
Bristol-Myers Squibb CoBMY56 funds$7.2B
McKesson CorpMCK56 funds$6.9B
Gilead Sciences IncGILD55 funds$10.1B
Boston Scientific CorpBSX55 funds$8.0B
Cytokinetics IncCYTK55 funds$1.5B

Ranked by how many of LXEO's tracked holders also hold each name. The last column is those co-holders' combined reported position in that name, not in LXEO.

Insider activity (Form 4)

Full insider page →
Sells · 180d
$636K
4 insiders
Net · 180d
-$636K
10 open-market transactions
DateInsiderRoleActionSharesValue
Aug 18, 2026Otero Jose ManuelChief Operating OfficerSell (S)1K$6K
Aug 18, 2026Townsend Richard NolanChief Executive Officer, DirectorSell (S)3K$17K
Aug 18, 2026Tamayo Louis EdwardChief Financial OfficerSell (S)4K$20K
Jul 1, 2026Otero Jose ManuelChief Operating OfficerSell (S)5K$21K
Jul 1, 2026Bhalla Narinder PalChief Medical OfficerSell (S)22K$99K
Jul 1, 2026Townsend Richard NolanChief Executive Officer, DirectorSell (S)26K$116K
Jul 1, 2026Tamayo Louis EdwardChief Financial OfficerSell (S)5K$21K
May 18, 2026Otero Jose ManuelChief Operating OfficerSell (S)1K$7K
May 18, 2026Townsend Richard NolanChief Executive Officer, DirectorSell (S)3K$17K
Apr 6, 2026Townsend Richard NolanChief Executive Officer, DirectorSell (S)55K$313K
Feb 18, 2026Townsend Richard NolanChief Executive Officer, DirectorSell (S)10K$65K
Feb 18, 2026Otero Jose ManuelChief Operating OfficerSell (S)3K$19K

Do institutions, insiders and Congress agree?

Mixed signals

Where institutional funds (13F), corporate insiders (Form 4) and US House members (STOCK Act) are buying or selling the same name in the same window. Green is buying, red is selling.

SEC EDGAR 13F + Form 4 + US House STOCK Act{ }get_ticker_confluence · API & MCP

Signals by source

Insiders and Congress: last 180 days. Funds: latest 13F, top 100 holders incl. passive

SourceBuyingSellingNet
13F funds
Top 100 holders by value, passive included; the hero counts active managers only
4630
Insiders
Form 4 open-market
04-$636K
US House
STOCK Act trades
00$0
Sector rotation
LXEO is in Health Care, which smart money is rotating OUT OF
$4.1B

Capital Rotation reports where institutional capital disclosed rotating, as of the latest public SEC 13F filings. It is data, not investment advice, a recommendation, or a prediction. Filings lag about 45 days and cover long US equity positions only. Past disclosed flows do not indicate future prices. Do your own research; consult a licensed advisor.

Institutional ownership over time

47 tracked filers in Q2 2026 filingsstill filing
066132Q3 2024Q1 2025Q3 2025Q1 2026Q2 2026
tracked filers holding their reported valueQ2 2026 filings so far: $82.2M
Each bar counts tracked filers with a position in that quarter's filings, so the newest bar excludes filers still on an earlier quarter. Arkolith's tracked universe has grown over this window; part of any long-run rise is coverage, not new buyers.

Recent filings

15 most recent

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Connected entities for LXEO

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Ask your agent what changed in LXEO

This stock page is the public Follow view. For one current, evidence-backed answer, use capital_change_brief through REST or MCP. It compares tracked 13F changes with qualifying Form 4 activity and cites the SEC evidence.

Copy-paste
curl -H "Authorization: Bearer YOUR_API_KEY" \
  "https://arkolith.com/api/v1/stocks/LXEO/capital-change-brief"
Ask your agent
Use Arkolith's capital_change_brief for LXEO.
Tell me what changed, whether insider activity
corroborates it, and cite the SEC evidence.

13F holdings + Form 4 insider transactions + the live filing stream, joined for LXEO. Filings are public domain, sourced to SEC EDGAR.