Arkolith/Funds/ADAR1 Capital Management, LLC

ADAR1 Capital Management, LLC

CIK 1940272
Holdings as of Mar 31, 2026·disclosed May 18, 2026·~48-day 13F lag·One quarter behind·13F-HR
Inactive

ADAR1 Capital Management, LLC holds a diversified book of 294 reported positions worth $1.7B as of Q1 2026 (disclosed May 18, 2026, a ~48-day 13F lag). This quarter Helix Acquisition Corp-CL A first appears in 13F filings (one of 5 new listings in the book), a listing rather than a purchase; they opened Beam Therapeutics Inc and trimmed Protagonist Therapeutics Inc. Their largest long position is Abivax Sa-ADR at 9% of the reported non-option book. They also disclosed $12.5M in put options (a bearish bet) and $22.2M in call options (bullish), shown separately below and excluded from the non-option book. Cloning the disclosed picks since 2024 would be +133% (+38.6%/yr). That is a simulation of the disclosed long book, not audited returns.

Opened
70
bought for the first time
+67 more · largest first
5 newly reportable · first quarter we see the security in 13F filings, a listing not a purchase
Added to
98
already held, bought more
+95 more · largest first

Growth of $10,000: cloning the disclosed book

If you'd copied them
+132.5%
+38.6%/yr · since Feb '24
Their reported book
+184.9%
held from quarter-end
S&P 500
+57.5%
same window
$9K$12K$16K$20K$24KFeb '24Aug '24Feb '25Sep '25Mar '26Sep '26
ADAR1 Capital Management, LLC (copied at disclosure) S&P 500

The reported book (valued from quarter-end) returned +184.9%, a 52.4-point gap that is the cost of the ~48-day 13F disclosure lag a real follower can't avoid.

Growth of $10,000 cloning ADAR1 Capital Management, LLC's disclosed long 13F book, rebalanced on each filing date (so it reflects each quarter's actual reporting lag, ~48 days for the latest filing, with no look-ahead), total-return basis (dividends reinvested), derived from end-of-day prices. “Their reported book” values the same picks from quarter-end, before they were public. S&P 500 is SPY total return over the same window. Excludes shorts, cash, options and non-13F holdings. Not investment advice.

How much sits in the biggest positions

Top-heavy: diversified book

Top 5 holdings
28%
Top 10 holdings
40%
Top 20 holdings
54%

Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.

Where the money is, by sector

89% mapped to company sectors

Health Care
87%
ETFs / funds
6%
No sector on file yet
5%
Financials
2%

+5 sectors below the cut, 1% together

Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.

Biggest moves: latest quarter

Estimated $ traded · quarter-end prices (an exit at the prior quarter-end), no cost basis

Bought
Trimmed / exited
Newly reportable· first quarter we see the security in 13F filings · position value, not a trade

Funds with the most overlap

Other tracked managers holding the same core names as ADAR1 Capital Management, LLC

Manager / fundShared namesTheir $ in those
Patient Square Capital LP8 / 80$420.0M
First Turn Management, LLC13 / 80$511.4M
TCG Crossover Management, LLC12 / 80$2.0B
Kynam Capital Management, LP8 / 80$794.6M
Artia Global Partners LP13 / 80$227.4M
Affinity Asset Advisors, LLC32 / 80$779.3M
Act Capital Management, LLC9 / 80$61.0M
Superstring Capital Management LP11 / 80$62.8M

Ranked by the share of each fund's own book sitting in the names it shares with ADAR1 Capital Management, LLC: only funds sharing at least a tenth of the book qualify. Index giants, bank custody books and market makers are excluded. They hold everything, so their overlap says nothing.

Holdings: largest first

Bars show each position's share of the portfolio. Click a row for its position history.

294 positions
#SecurityValueShares% PortLast moveHistory
1Abivax Sa
SPONSORED ADS
$155.2M1.39M
9.3%
+5.8%
Added · +77K sh
2Protagonist Therapeutics Inc
COM
$104.8M994.1K
6.3%
−5.2%
Reduced · −55K sh
3Roivant Sciences Ltd
SHS
$91.0M3.29M
5.5%
−4.2%
Reduced · −143K sh
4Immunovant Inc
COM
$66.5M2.68M
4.0%
+8.0%
Added · +198K sh
5State STR SPDR S&P 500 ETF T
TR UNIT
$49.4M75.9K
3.0%
+39%
Added · +21K sh
6Terns Pharmaceuticals Inc
COM
$48.2M914.7K
2.9%
+69%
Added · +373K sh
7Cytokinetics Inc
COM NEW
$41.7M632.6K
2.5%
+17%
Added · +92K sh
8Crinetics Pharmaceuticals In
COM
$41.4M1.14M
2.5%
+268%
Added · +830K sh
9Ea Series Trust
ALPHA ARCH 1-3
$39.2M337.1K
2.4%
Held
10Denali Therapeutics Inc
COM
$35.9M1.87M
2.2%
36×
Added · +1.8M sh
11Beam Therapeutics Inc
COM
$34.5M1.45M
2.1%
New
New position
12Zai Lab Ltd
ADR
$26.8M1.43M
1.6%
+14%
Added · +179K sh
13Septerna Inc
COM
$26.2M1.09M
1.6%
−5.8%
Reduced · −68K sh
14Vir Biotechnology Inc
COM
$24.6M2.74M
1.5%
New
New position
15DBV Technologies S A
SPONSORED ADS
$21.2M1.01M
1.3%
New
New position
16Anteris Technologies Global
COM
$21.0M3.79M
1.3%
+206%
Added · +2.6M sh
17Inspire Med Sys Inc
COM
$20.9M405.2K
1.3%
27×
Added · +390K sh
18Scholar Rock Hldg Corp
COM
$20.0M407.3K
1.2%
+485%
Added · +338K sh
19Rhythm Pharmaceuticals Inc
COM
$18.4M211.4K
1.1%
+312%
Added · +160K sh
20Spyre Therapeutics Inc
COM NEW
$17.1M338.3K
1.0%
+894%
Added · +304K sh
21Cytomx Therapeutics Inc.
COM
$16.0M3.41M
1.0%
−18%
Reduced · −773K sh
22Prothena Corp PLC
SHS
$15.4M1.58M
0.9%
+8.5%
Added · +124K sh
23Sanofi Sa
SPONSORED ADR
$15.3M316.9K
0.9%
+399%
Added · +253K sh
24Vaxcyte Inc
COM
$15.1M259.1K
0.9%
−18%
Reduced · −57K sh
25Monopar Therapeutics Inc
COM NEW
$14.5M264.3K
0.9%
+13%
Added · +30K sh
26Arbutus Biopharma Corp
COM
$14.1M3.13M
0.8%
−42%
Reduced · −2.3M sh
27Amylyx Pharmaceuticals Inc
COM
$13.9M1.00M
0.8%
+12%
Added · +110K sh
28Celldex Therapeutics Inc New
COM NEW
$13.6M427.8K
0.8%
−34%
Reduced · −219K sh
29Taysha Gene Therapies Inc
COM SHS
$13.3M2.98M
0.8%
+19%
Added · +484K sh
30Xenon Pharmaceuticals Inc
COM
$13.3M228.9K
0.8%
+12%
Added · +25K sh
31Sutro Biopharma Inc
COM SHS
$13.1M524.4K
0.8%
+682%
Added · +457K sh
32Revolution Medicines Inc
COM
$13.0M133.9K
0.8%
−7.7%
Reduced · −11K sh
33Enliven Therapeutics Inc
COM
$12.9M329.5K
0.8%
11×
Added · +300K sh
34CG Oncology Inc
COM
$12.6M185.7K
0.8%
−28%
Reduced · −72K sh
35SPDR Series Trust
STATE STREET SPD
$12.4M135.6K
0.7%
Held
36Establishment Labs Hldgs Inc
COM
$12.1M213.5K
0.7%
+25%
Added · +42K sh
37Replimune Group Inc
COM
$12.1M1.58M
0.7%
+28%
Added · +342K sh
38Inventiva Sa
ADS
$12.1M2.17M
0.7%
−20%
Reduced · −535K sh
39Ionis Pharmaceuticals Inc
COM
$12.0M160.3K
0.7%
+9.0%
Added · +13K sh
40Nektar Therapeutics
COM NEW
$11.6M161.3K
0.7%
+124%
Added · +89K sh
41Inhibikase Therapeutics Inc
COM NEW
$11.1M6.61M
0.7%
−18%
Reduced · −1.5M sh
42Ars Pharmaceuticals Inc
COM
$10.9M1.36M
0.7%
+268%
Added · +992K sh
43Helix Acquisition Corp III
USD CL A ORD SHS
$10.3M1.00M
0.6%
Listed
Newly reportable
44Ovid Therapeutics Inc
COM
$10.1M4.54M
0.6%
+6.0%
Added · +259K sh
45Onkure Therapeutics Inc
COM CL A
$10.1M2.43M
0.6%
+140%
Added · +1.4M sh
46Regeneron Pharmaceuticals
COM
$9.4M12.2K
0.6%
+0.8%
Added · +103 sh
47Moonlake Immunotherapeutics
CLASS A ORD
$8.5M457.1K
0.5%
New
New position
48Lexeo Therapeutics Inc
COM
$8.4M1.47M
0.5%
+5.3%
Added · +74K sh
49Opus Genetics Inc
COM
$8.4M1.85M
0.5%
46×
Added · +1.8M sh
50Teva Pharmaceutical Inds Ltd
SPONSORED ADS
$8.1M268.4K
0.5%
+14%
Added · +32K sh
Showing 50 of 294 positions
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Largest options & derivatives disclosed

Put / call positions from the 13F — totals include every disclosed option leg

Put notional (bearish)$12.5M
Call notional (bullish)$22.2M
TypeUnderlyingNotional valueUnderlying shares
CALL · bullishTERNS PHARMACEUTICALS INC430$10.5M200K
PUT · bearishISHARES RUSSELL 2000 ETFIWM$6.8M28K
CALL · bullishABIVAX SA-ADRABVX$4.9M44K
PUT · bearishLIQUIDIA CORPLQDA$3.8M100K
PUT · bearishSS SPDR S&P BIOTECH ETFXBI$1.9M15K
CALL · bullishUNIQURE NVQURE$1.6M100K
CALL · bullishKARYOPHARM THERAPEUTICS INCKPTI$1.1M205K
CALL · bullishKEEN VISION ACQUISITION CORPKVAC$900K75K
CALL · bullishREPLIMUNE GROUP INCREPL$765K100K
CALL · bullishFRACTYL HEALTH INCGUTS$654K1.4M
CALL · bullishNOVO-NORDISK A/S-SPONS ADRNVO$478K13K
CALL · bullishULTRAGENYX PHARMACEUTICAL INRARE$419K20K
CALL · bullishMOONLAKE IMMUNOTHERAPEUTICSMLTX$373K20K
CALL · bullishCORBUS PHARMACEUTICALS HOLDICRBP$329K35K
CALL · bullishSOLIDION TECHNOLOGY INCSTI$85K14K
PUT · bearishQUINCE THERAPEUTICS INC$5K50K

13F filers disclose option positions at the market value of the underlying the contracts reference, not the premium paid. A put is a bearish bet (it gains if the stock falls); a call is bullish. “Underlying shares” is the share count the contracts control, not a share holding. These legs are excluded from the non-option book, weighting, concentration and sector figures above.

Filing history

As-of date vs the date the SEC received each filing

$1.7B · Q1 2026Q4 2023 · $279.8MQ1 2026 · $1.7B

Reported 13F total per quarter. Raw filing totals can include option notional.

QuarterAs ofFiledLagPositionsValueForm
Q1 2026Mar 31, 2026May 18, 202648d311$1.7B13F-HR
Q4 2025Dec 31, 2025Feb 18, 202649d270$1.4B13F-HR/A
Q3 2025Sep 30, 2025Nov 14, 202545d220$1.1B13F-HR
Q2 2025Jun 30, 2025Aug 14, 202545d210$652.1M13F-HR
Q1 2025Mar 31, 2025May 15, 202545d202$538.7M13F-HR
Q4 2024Dec 31, 2024Feb 13, 202544d214$500.4M13F-HR
Q3 2024Sep 30, 2024Nov 14, 202445d278$614.9M13F-HR
Q2 2024Jun 30, 2024Aug 13, 202444d266$529.7M13F-HR
Q1 2024Mar 31, 2024May 15, 202445d261$440.8M13F-HR
Q4 2023Dec 31, 2023Feb 14, 202445d170$279.8M13F-HR
Amended / restated
  • Q4 2025 · filed Feb 17, 202613F-HR · superseded

Data source

Holdings from SEC EDGAR 13F-HR filings, updated quarterly, filed up to 45 days after quarter-end. Public domain. Book totals and portfolio weights cover reported non-option positions, which can include notes and warrants. Disclosed put/call options are listed separately and excluded from those totals. The performance line is a simulation of the disclosed long book, not an audited return.