Arkolith/Funds/ADAR1 Capital Management, LLC

ADAR1 Capital Management, LLC

CIK 1940272
Holdings as of Mar 31, 2026·disclosed May 18, 2026·~48-day 13F lag·13F-HR
Inactive

ADAR1 Capital Management, LLC holds a diversified book of 290 stocks worth $1.7B as of Q1 2026 (disclosed May 18, 2026, a ~45-day 13F lag). This quarter they opened BEAM THERAPEUTICS INC and trimmed PROTAGONIST THERAPEUTICS INC. Their largest long position is ABIVAX SA at 9% of the equity book. They also disclosed $12.5M in put options (a bearish bet) and $22.2M in call options (bullish), shown separately below and excluded from the equity book.

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Use Arkolith to show ADAR1 Capital Management, LLC's latest
holdings, largest changes, and filing provenance.
Opened
63
new positions
Added to
106
existing
Trimmed
59
reduced
Sold out
29
exited

Concentration

Top-heavy: diversified book

Top 5 holdings
28%
Top 10 holdings
40%
Top 20 holdings
55%

Share of the disclosed book in its largest positions. A higher top-5 share means a more concentrated, higher-conviction portfolio.

Direct sector allocation

19% mapped to company sectors

ETF / fund or unclassified
81%
Health Care
18%
Financials
0%
Industrials
0%
Consumer Discretionary
0%

Direct operating-company sectors from our SIC-based security master. ETF/fund and unclassified holdings stay visible separately; this is not ETF look-through exposure.

Biggest moves: latest quarter

Estimated $ traded · quarter-end prices, no cost basis

Bought
  • DENALI THERAPEUTICS INC
    36×$34.9M
  • BEAM THERAPEUTICS INC
    New$34.5M
  • CRINETICS PHARMACEUTICALS IN
    +268%$30.1M
  • VIR BIOTECHNOLOGY INC
    New$24.6M
  • DBV TECHNOLOGIES S A
    New$21.2M
  • INSPIRE MED SYS INC
    27×$20.1M
Trimmed / exited

Holdings: largest first

Bars show each stock's share of the portfolio. Click a row for its position history.

294 positions
#SecurityValueShares% PortLast moveHistory
1Abivax Sa
SPONSORED ADS
$155.2M1.39M
9.3%
+5.8%
Added · +77K sh
2Protagonist Therapeutics Inc
COM
$104.8M994.1K
6.3%
−5.2%
Reduced · −55K sh
3Roivant Sciences Ltd
SHS
$91.0M3.29M
5.5%
−4.2%
Reduced · −143K sh
4Immunovant Inc
COM
$66.5M2.68M
4.0%
+8.0%
Added · +198K sh
5State STR SPDR S&P 500 ETF T
TR UNIT
$49.4M75.9K
3.0%
+39%
Added · +21K sh
6Terns Pharmaceuticals Inc
COM
$48.2M914.7K
2.9%
+69%
Added · +373K sh
7Cytokinetics Inc
COM NEW
$41.7M632.6K
2.5%
+17%
Added · +92K sh
8Crinetics Pharmaceuticals In
COM
$41.4M1.14M
2.5%
+268%
Added · +830K sh
9Ea Series Trust
ALPHA ARCH 1-3
$39.2M337.1K
2.4%
Held
10Denali Therapeutics Inc
COM
$35.9M1.87M
2.2%
36×
Added · +1.8M sh
11Beam Therapeutics Inc
COM
$34.5M1.45M
2.1%
New
New position
12Zai Lab Ltd
ADR
$26.8M1.43M
1.6%
+14%
Added · +179K sh
13Septerna Inc
COM
$26.2M1.09M
1.6%
−5.8%
Reduced · −68K sh
14Vir Biotechnology Inc
COM
$24.6M2.74M
1.5%
New
New position
15DBV Technologies S A
SPONSORED ADS
$21.2M1.01M
1.3%
New
New position
16Anteris Technologies Global
COM
$21.0M3.79M
1.3%
+206%
Added · +2.6M sh
17Inspire Med Sys Inc
COM
$20.9M405.2K
1.3%
27×
Added · +390K sh
18Scholar Rock Hldg Corp
COM
$20.0M407.3K
1.2%
+485%
Added · +338K sh
19Rhythm Pharmaceuticals Inc
COM
$18.4M211.4K
1.1%
+312%
Added · +160K sh
20Spyre Therapeutics Inc
COM NEW
$17.1M338.3K
1.0%
+894%
Added · +304K sh
21Cytomx Therapeutics Inc.
COM
$16.0M3.41M
1.0%
−18%
Reduced · −773K sh
22Prothena Corp PLC
SHS
$15.4M1.58M
0.9%
+8.5%
Added · +124K sh
23Sanofi Sa
SPONSORED ADR
$15.3M316.9K
0.9%
+399%
Added · +253K sh
24Vaxcyte Inc
COM
$15.1M259.1K
0.9%
−18%
Reduced · −57K sh
25Monopar Therapeutics Inc
COM NEW
$14.5M264.3K
0.9%
+13%
Added · +30K sh
26Arbutus Biopharma Corp
COM
$14.1M3.13M
0.8%
−42%
Reduced · −2.3M sh
27Amylyx Pharmaceuticals Inc
COM
$13.9M1.00M
0.8%
+12%
Added · +110K sh
28Celldex Therapeutics Inc New
COM NEW
$13.6M427.8K
0.8%
−34%
Reduced · −219K sh
29Taysha Gene Therapies Inc
COM SHS
$13.3M2.98M
0.8%
+19%
Added · +484K sh
30Xenon Pharmaceuticals Inc
COM
$13.3M228.9K
0.8%
+12%
Added · +25K sh
31Sutro Biopharma Inc
COM SHS
$13.1M524.4K
0.8%
+682%
Added · +457K sh
32Revolution Medicines Inc
COM
$13.0M133.9K
0.8%
−7.7%
Reduced · −11K sh
33Enliven Therapeutics Inc
COM
$12.9M329.5K
0.8%
11×
Added · +300K sh
34CG Oncology Inc
COM
$12.6M185.7K
0.8%
−28%
Reduced · −72K sh
35SPDR Series Trust
STATE STREET SPD
$12.4M135.6K
0.7%
Held
36Establishment Labs Hldgs Inc
COM
$12.1M213.5K
0.7%
+25%
Added · +42K sh
37Replimune Group Inc
COM
$12.1M1.58M
0.7%
+28%
Added · +342K sh
38Inventiva Sa
ADS
$12.1M2.17M
0.7%
−20%
Reduced · −535K sh
39Ionis Pharmaceuticals Inc
COM
$12.0M160.3K
0.7%
+9.0%
Added · +13K sh
40Nektar Therapeutics
COM NEW
$11.6M161.3K
0.7%
+124%
Added · +89K sh
41Inhibikase Therapeutics Inc
COM NEW
$11.1M6.61M
0.7%
−18%
Reduced · −1.5M sh
42Ars Pharmaceuticals Inc
COM
$10.9M1.36M
0.7%
+268%
Added · +992K sh
43Helix Acquisition Corp III
USD CL A ORD SHS
$10.3M1.00M
0.6%
New
New position
44Ovid Therapeutics Inc
COM
$10.1M4.54M
0.6%
+6.0%
Added · +259K sh
45Onkure Therapeutics Inc
COM CL A
$10.1M2.43M
0.6%
+140%
Added · +1.4M sh
46Regeneron Pharmaceuticals
COM
$9.4M12.2K
0.6%
+0.8%
Added · +103 sh
47Moonlake Immunotherapeutics
CLASS A ORD
$8.5M457.1K
0.5%
Added
Added · +457K sh
48Lexeo Therapeutics Inc
COM
$8.4M1.47M
0.5%
+5.3%
Added · +74K sh
49Opus Genetics Inc
COM
$8.4M1.85M
0.5%
46×
Added · +1.8M sh
50Teva Pharmaceutical Inds Ltd
SPONSORED ADS
$8.1M268.4K
0.5%
+14%
Added · +32K sh
Showing 50 of 294 positions

Largest options & derivatives disclosed

Put / call positions from the 13F — totals include every disclosed option leg

Put notional (bearish)$12.5M
Call notional (bullish)$22.2M
TypeUnderlyingNotional valueUnderlying shares
CALL · bullishTERNS PHARMACEUTICALS INC$10.5M200K
PUT · bearishISHARES RUSSELL 2000 ETFIWM$6.8M28K
CALL · bullishABIVAX SA$4.9M44K
PUT · bearishLIQUIDIA CORPORATION$3.8M100K
PUT · bearishSPDR SERIES TRUST$1.9M15K
CALL · bullishUNIQURE NV$1.6M100K
CALL · bullishKARYOPHARM THERAPEUTICS INC$1.1M205K
CALL · bullishKEEN VISION ACQUISITION CORPKVAC$900K75K
CALL · bullishREPLIMUNE GROUP INC$765K100K
CALL · bullishFRACTYL HEALTH INCGUTS$654K1.4M
CALL · bullishNOVO-NORDISK A/S-SPONS ADRNVO$478K13K
CALL · bullishULTRAGENYX PHARMACEUTICAL INRARE$419K20K
CALL · bullishMOONLAKE IMMUNOTHERAPEUTICS$373K20K
CALL · bullishCORBUS PHARMACEUTICALS HLDGS$329K35K
CALL · bullishSOLIDION TECHNOLOGY INC$85K14K
PUT · bearishQUINCE THERAPEUTICS INC$5K50K

13F filers disclose option positions at the market value of the underlying the contracts reference, not the premium paid. A put is a bearish bet (it gains if the stock falls); a call is bullish. “Underlying shares” is the share count the contracts control, not a share holding. These legs are excluded from the equity book, weighting, concentration and sector figures above.

Filing history

As-of date vs the date the SEC received each filing

QuarterAs ofFiledPositionsValueForm
Q1 2026Mar 31, 2026May 18, 2026311$1.7B13F-HR
Q4 2025Dec 31, 2025Feb 18, 2026270$1.4B13F-HR/A
Q3 2025Sep 30, 2025Nov 14, 2025220$1.1B13F-HR
Q2 2025Jun 30, 2025Aug 14, 2025210$652.1M13F-HR
Q1 2025Mar 31, 2025May 15, 2025202$538.7M13F-HR
Q4 2024Dec 31, 2024Feb 13, 2025214$500.4M13F-HR
Q3 2024Sep 30, 2024Nov 14, 2024278$614.9M13F-HR
Q2 2024Jun 30, 2024Aug 13, 2024266$529.7M13F-HR
Q1 2024Mar 31, 2024May 15, 2024261$440.8M13F-HR
Q4 2023Dec 31, 2023Feb 14, 2024170$279.8M13F-HR
Amended / restated
  • Q4 2025 · filed Feb 17, 202613F-HR · superseded

Data source

Holdings from SEC EDGAR 13F-HR filings, updated quarterly ~45 days after quarter-end. Public domain. The book and weighting are long equity only; disclosed put/call options are listed separately and excluded from those totals. The performance line is a simulation of the disclosed long book, not an audited return.